Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kyrie Felio"'
Publikováno v:
Blood. 118:3870-3878
Group 1 CD1 (CD1a, -b, and -c) presents self and foreign lipid antigens to multiple T-cell subsets in humans. However, in the absence of a suitable animal model, the specific functions and developmental requirements of these T cells remain unknown. T
Publikováno v:
The Journal of Immunology. 176:1421-1430
Invariant NK T (iNKT) cells are a distinct subset of T cells that rapidly produce an array of immunoregulatory cytokines upon activation. Cytokines produced by iNKT cells subsequently transactivate other leukocytes and elicit their respective effecto
Autor:
Mark M. Davis, Kyrie Felio, Changqing Wang, Hagop M. Kantarjian, Peter P. Lee, Jeffrey J. Molldrem, Richard E. Champlin
Publikováno v:
Nature Medicine. 6:1018-1023
Although the immune system has long been implicated in the control of cancer, evidence for specific and efficacious immune responses in human cancer has been lacking. In the case of chronic myelogenous leukemia (CML), either allogeneic bone marrow tr
Autor:
Kyrie Felio, Pramod K. Giri, Yanbiao Geng, Sha Li, Hak Jong Choi, Chyung Ru Wang, Hoonsik Cho
Publikováno v:
Blood. 117(6)
E26 Transformation specific (Ets) family transcription factors control the expression of a large number of genes regulating hematopoietic cell development and function. Two such transcription factors, Ets-1 and myeloid Elf-1–like factor (MEF), have
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 186(1)
CD8(+) T cells restricted to MHC class Ib molecules other than H2-M3 have been shown to recognize bacterial Ags. However, the contribution of these T cells to immune responses against bacterial infection is not well defined. To investigate the immune
Autor:
Michael Zimmer, Sha Li, Kyrie Felio, D. Branch Moody, Angela Colmone, Chyung Ru Wang, Christopher C. Dascher, Hanh Nguyen, Michael B. Brenner, Hak Jong Choi
Publikováno v:
The Journal of Experimental Medicine
Group 1 CD1 (CD1a, CD1b, and CD1c)–restricted T cells recognize mycobacterial lipid antigens and are found at higher frequencies in Mycobacterium tuberculosis (Mtb)–infected individuals. However, their role and dynamics during infection remain un
Autor:
Maria-Luisa Alegre, Bin Wang, Chyung Ru Wang, Angela Colmone, Kyrie Felio, Hak Jong Choi, Honglin Xu, Ping Zhou, Michael Zimmer, Hanh Nguyen
CD1 proteins constitute a distinct lineage of antigen-presenting molecules specialized for the presentation of lipid antigens to T cells. In contrast to the extensive sequence polymorphism characteristic of classical MHC molecules, CD1 proteins exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdba44bf3d1f4c37c889c4fdbc2a81e2
https://europepmc.org/articles/PMC2644137/
https://europepmc.org/articles/PMC2644137/
Autor:
Kyrie Felio, Hanh Nguyen, Christopher C Dascher, Hak-Jong Choi, Sha Li, Michael I Zimmer, Michael B Brenner, Chyung-Ru Wang
Publikováno v:
The Journal of Immunology. 182:45.31-45.31
Group 1 CD1 presents mycobacterial lipid antigens to various T cell subsets. Although group 1 CD1-restricted responses have been implicated in anti-mycobacterial immunity in humans, little is known about their function, as mice lack group 1 CD1. To s