Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kyriaki Marcou"'
Autor:
Susanna Campesan, Ivana del Popolo, Kyriaki Marcou, Anna Straatman-Iwanowska, Mariaelena Repici, Kalina V. Boytcheva, Victoria E. Cotton, Natalie Allcock, Ezio Rosato, Charalambos P. Kyriacou, Flaviano Giorgini
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106236- (2023)
Huntington's disease (HD) is a fatal neurodegenerative disease with limited treatment options. Human and animal studies have suggested that metabolic and mitochondrial dysfunctions contribute to HD pathogenesis. Here, we use high-resolution respirome
Externí odkaz:
https://doaj.org/article/f244b257c55740d4955b65669107d32b
Autor:
Susanna Campesan, Charalambos P. Kyriacou, Anna Straatman-Iwanowska, Victoria E. Cotton, Flaviano Giorgini, Kyriaki Marcou
Publikováno v:
Pathogenic mechanisms.
Background Metabolic dysfunction is a hallmark of HD pathology. Decreased glucose metabolism and increased lactate concentrations in HD brains suggest mitochondrial involvement in the disease. Moreover, alterations in mitochondrial fission/fusion bal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b10c821f68ed75e38b862168f8c2c3a6
https://doi.org/10.1136/jnnp-2018-ehdn.36
https://doi.org/10.1136/jnnp-2018-ehdn.36