Zobrazeno 1 - 10
of 487
pro vyhledávání: '"Kyriacos A Athanasiou"'
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195261 (2018)
Bone-to-bone integration can be obtained by osteoconductive ceramics such as hydroxyapatite (HAp) and beta-tricalcium phosphate (β-TCP), but cartilage-to-cartilage integration is notoriously difficult. Many cartilage repair therapies, including micr
Externí odkaz:
https://doaj.org/article/405e94a898c743a38285c6a419725cfa
Autor:
Heenam Kwon, Anne K Haudenschild, Wendy E Brown, Natalia Vapniarsky, Nikolaos K Paschos, Boaz Arzi, Jerry C Hu, Kyriacos A Athanasiou
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182531 (2017)
Abundance and accessibility render skin-derived stem cells an attractive cell source for tissue engineering applications. Toward assessing their utility, the variability of constructs engineered from human dermis-isolated adult stem (hDIAS) cells was
Externí odkaz:
https://doaj.org/article/9458cb2bd2a0496eaff2bf17926f8448
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98570 (2014)
Dermis isolated adult stem (DIAS) cells, a subpopulation of dermis cells capable of chondrogenic differentiation in the presence of cartilage extracellular matrix, are a promising source of autologous cells for tissue engineering. Hypoxia, through kn
Externí odkaz:
https://doaj.org/article/b5a4500f183d4bde8e23d264b69a5313
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56983 (2013)
The insufficient healing capacity of articular cartilage necessitates mechanically functional biologic tissue replacements. Using cells to form biomimetic cartilage implants is met with the challenges of cell scarcity and donor site morbidity, requir
Externí odkaz:
https://doaj.org/article/85a9912e8cfa4b578fcf2321df217c32
Autor:
Daniel J Huey, Kyriacos A Athanasiou
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27857 (2011)
This study aimed to improve the functional properties of anatomically-shaped meniscus constructs through simultaneous tension and compression mechanical stimulation in conjunction with chemical stimulation.Scaffoldless meniscal constructs were subjec
Externí odkaz:
https://doaj.org/article/a5e0eb5ba8504160b04150376703e07a
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26178 (2011)
The major connective tissues of the knee joint act in concert during locomotion to provide joint stability, smooth articulation, shock absorption, and distribution of mechanical stresses. These functions are largely conferred by the intrinsic materia
Externí odkaz:
https://doaj.org/article/d514d0a421c645c4bdc0325d3b195576
Autor:
Gidon Ofek, Christopher M Revell, Jerry C Hu, David D Allison, K Jane Grande-Allen, Kyriacos A Athanasiou
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2795 (2008)
Articular cartilage is a highly functional tissue which covers the ends of long bones and serves to ensure proper joint movement. A tissue engineering approach that recapitulates the developmental characteristics of articular cartilage can be used to
Externí odkaz:
https://doaj.org/article/b2455030ff52437094ff6b2aa440ef07
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2341 (2008)
Hydrostatic pressure (HP) is a significant factor in the function of many tissues, including cartilage, knee meniscus, temporomandibular joint disc, intervertebral disc, bone, bladder, and vasculature. Though studies have been performed in assessing
Externí odkaz:
https://doaj.org/article/78c51e14032f4ab98ff02c631fda0434
The Effect of Neonatal, Juvenile, and Adult Donors on Rejuvenated Neocartilage Functional Properties
Autor:
Kyriacos A. Athanasiou, Benjamin J. Bielajew, Ryan P. Donahue, Rachel C. Nordberg, Jerry C. Hu
Publikováno v:
Tissue Eng Part A
Tissue engineering. Part A, vol 28, iss 9-10
Tissue engineering. Part A, vol 28, iss 9-10
Cartilage does not naturally heal, and cartilage lesions from trauma and wear-and-tear can lead to eventual osteoarthritis. To address long-term repair, tissue engineering of functional biologic implants to treat cartilage lesions is desirable, but t
Publikováno v:
Tissue Engineering Part A.