Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kyra O'Sullivan"'
Autor:
Christine J. Cardin, Kyra O'Sullivan, Fergus E. Poynton, Susan J. Quinn, Igor V. Sazanovich, Páraic M. Keane, Thorfinnur Gunnlaugsson, Bjørn la Cour Poulsen, Michael W. George, Xue-Zhong Sun, Michael Towrie, John M. Kelly
Publikováno v:
Chemical Science
Ruthenium polypyridyl complexes which can sensitise the photo-oxidation of nucleic acids and other biological molecules show potential for photo-therapeutic applications. In this article a combination of transient visible absorption (TrA) and time-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9b5020b373d980facd1602072db54a
Autor:
Cora Alberti, J. Sanchez-Weatherby, Kyra O’Sullivan, John A. Brazier, Christine J. Cardin, Graeme Winter, David J. Cardin, Caroline Hurtado Quimper, John M. Kelly, James P. Hall, Thomas Sorensen
Publikováno v:
Journal of the American Chemical Society. 136:17505-17512
Hydration-dependent DNA deformation has been known since Rosalind Franklin recognized that the relative humidity of the sample had to be maintained to observe a single conformation in DNA fiber diffraction. We now report for the first time the crysta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b054d0275212d6d5ede079941195cc
https://doi.org/10.1021/ja508745x
https://doi.org/10.1021/ja508745x
Autor:
Christine J. Cardin, Abeer Naseer, James P. Hall, Kyra O'Sullivan, Jayden A. Smith, John M. Kelly
Publikováno v:
Proceedings of the National Academy of Sciences. 108:17610-17614
We describe a crystal structure, at atomic resolution (1.1 Å, 100 K), of a ruthenium polypyridyl complex bound to duplex DNA, in which one ligand acts as a wedge in the minor groove, resulting in the 51° kinking of the double helix. The complex ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db2b5f62d816bac3b996eb2287e02e0c
https://doi.org/10.1073/pnas.1108685108
https://doi.org/10.1073/pnas.1108685108
Autor:
Kyra O'Sullivan, John M. Kelly, Graeme Winter, Thomas Sorensen, Christine J. Cardin, Hakan Niyazi, James P. Hall
The ruthenium complex [Ru(phen)2(dppz)] (where phen is a phenanthroline and dppz a dipyridyl–phenazine ligand) is\ud known as a ‘light switch’ complex because its luminescence in solution is significantly enhanced in the presence of DNA. This p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed07f4907fe5b3ffeae5682fd0576a41
https://centaur.reading.ac.uk/28457/7/Nature_Chem_accepted.pdf
https://centaur.reading.ac.uk/28457/7/Nature_Chem_accepted.pdf
Autor:
Christine J. Cardin, Graeme Winter, John M. Kelly, James P. Hall, David J. Cardin, Juan Sanchez-Weatherby, Kyra O'Sullivan, Susan J. Quinn, Hakan Niyazi, Thomas Sorensen
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 70:C1377-C1377
Since the 1980s, there has been great interest in how polypyridyl ruthenium complexes bind to DNA. This is due to their photoactive properties[1], which have great potential in photodynamic therapy, as they are able to damage DNA upon photoirradiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8775f47b58df24f717f457d0d03e28f
https://doi.org/10.1107/s2053273314086227
https://doi.org/10.1107/s2053273314086227
Autor:
Kyra O'Sullivan, Graeme Winter, John M. Kelly, Hakan Niyazi, Christine J. Cardin, James P. Hall, David J. Cardin, Thomas Sorensen
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 69:s335-s335
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05048fcd5627ca93befba3c9f975fbbe
https://doi.org/10.1107/s0108767313097109
https://doi.org/10.1107/s0108767313097109