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pro vyhledávání: '"Kyra Geyer"'
Autor:
Alexandra A. Richter, Christopher-Nils Mais, Laura Czech, Kyra Geyer, Astrid Hoeppner, Sander H. J. Smits, Tobias J. Erb, Gert Bange, Erhard Bremer
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Bacteria frequently adapt to high osmolarity surroundings through the accumulation of compatible solutes. Ectoine is a prominent member of these types of stress protectants and is produced via an evolutionarily conserved biosynthetic pathway beginnin
Externí odkaz:
https://doaj.org/article/2a7437065e37451c9b031a2d68f60425
Publikováno v:
Biochemistry
Polyketide synthases (PKSs) are molecular assembly lines that condense basic chemical building blocks for the production of structurally diverse polyketides. Many PKS biosynthetic gene clusters contain a gene encoding for a type II thioesterase (TEII
Publikováno v:
Chembiochem
Polyketide synthases (PKSs) use simple extender units to synthesize complex natural products. A fundamental question is how different extender units are site‐specifically incorporated into the growing polyketide. Here we established phoslactomycin
Autor:
Kyra Geyer, Bastian Vögeli, Tobias J. Erb, Niña Socorro Cortina, Patrick D. Gerlinger, Sarah Benkstein
Publikováno v:
Cell Chemical Biology. 25:833-839.e4
Summary The incorporation of different extender units generates structural diversity in polyketides. There is significant interest in engineering substrate specificity of polyketide synthases (PKSs) to change their chemical structure. Efforts to chan