Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kyoya Takahata"'
Autor:
Eiji Morigaki, Yoshie Miura, Sakayu Shimizu, Miyako Nagao, Mikiro Tada, Naomichi Baba, Kyoya Takahata, Shuhei Nakajima
Publikováno v:
Bioscience, biotechnology, and biochemistry. 62(10)
Sphingomyelins and ceramides bearing a docosahexaenoyl or arachidonoyl group were synthesized from sphingosylphosphorylcholine and sphingosine, respectively, by dicyclohexylcarbodiimide-mediated acylation.
Publikováno v:
Epilepsy & Seizure. 4:7-14
Background: The Atkins diet modified for epilepsy patients (modified Atkins diet: MAD) was reported to be a substitute for the classical ketogenic diet. Recently, it has been shown that this diet is effective not only for intractable childhood epilep
Publikováno v:
Environmental Health and Preventive Medicine. 10:184-189
Docosahexaenoic acid (DHA) is known as a chemopreventive substance for cancers. Previously we reported that DHA induces apoptosis in HL-60 cells. The aim of this study was to clarify the role of phosphatidylinositol 3-kinase (PI3-kinase)/Akt signalin
Autor:
Yukimitsu Masamoto, Yasuaki Shimoishi, Kyoya Takahata, Yoshiyuki Murata, Mikiro Tada, Hideya Ando
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 67:631-634
A tyrosinase inhibitor was isolated from the seeds of Euphorbia lathyris L. by bioassay-guided fractionation and purification, using silica gel column chromatography. It was identified as esculetin by comparing its physical properties and spectral da
Publikováno v:
Life Sciences. 64:PL165-PL171
The effects of capsaicin on cellular growth and intracellular calcium mobilization were examined in human cervical carcinoma derivation, HeLa cells. Capsaicin inhibited cellular growth and increased intracellular calcium level in HeLa cells. This cap
Publikováno v:
Cytotechnology. 23:77-85
Transglutaminase catalyzes the intermolecular cross-linking of peptides between Gln and Lys residues, forming an e-(γ-glutamyl) lysine bond. Amyloid β-peptide, a major constituent of the deposits in Alzheimer disease, contains Lys16, Lys28, and Gln
Publikováno v:
Journal of Investigative Dermatology. 122:848-850
Autor:
Ferenc Gallyas, Masaya Nagao, Takeshi Tabira, Yoshihiro Konishi, Seiji Masuda, Kyoya Takahata, Ryuzo Sasaki
Publikováno v:
Europe PubMed Central
Radioiodinated erythropoietin (Epo) was bound specifically to the cells of two non-erythroid clonal lines, PC12 and SN6, which expressed neuronal characteristics. The binding was time-, cell number-, and dose-dependent and was reversible. Although th
Publikováno v:
ChemInform. 30
Sphingosine 1-phosphate was prepared from sphingosine by two steps involving conversion of sphingosine to phosphatidylsphingosine catalyzed by phospholipase D and enzymatic hydrolysis of the intermediate to a diacyglycerol and sphingosine 1-phosphate
Publikováno v:
FEBS Letters. 307:206-210
Okadaic acid (OA), a potent inhibitor of protein phosphatases type 1 and type 2A, inhibited thrombin-induced platelet aggregation (IC50 = 0.8 μM), [14C]serotonin release and increase in intracellular Ca2+ ([Ca2+]i) in the same dose dependence. In th