Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kyoung-Hwa Son"'
Autor:
Min-Young Kim, Jung-Young Shin, Jeong-Oh Kim, Kyoung-Hwa Son, Yeon Sil Kim, Chan Kwon Jung, Jin-Hyoung Kang
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Hypoxic tumors are known to be highly resistant to radiotherapy and cause poor prognosis in non-small cell lung cancer (NSCLC) patients. CKD-516, a novel vascular disrupting agent (VDA), mainly affects blood vessels in the central
Externí odkaz:
https://doaj.org/article/4378f3f5e1e8448784237686d3099f49
Publikováno v:
Anticancer Research. 41:4807-4820
Background/aim LY2835219 (LY), a novel CDK4/6 inhibitor, prevents cell proliferation through G1 arrest. Docetaxel (DTX) and paclitaxel (PTX) are cytotoxic drugs targeting tubulin-mediated apoptotic cell death via G2/M arrest. We evaluated the antitum
Publikováno v:
APPRAISAL STUDIES. 19:159-181
Autor:
Kyoung-Hwa Son, Jeong-Oh Kim, Chan Kwon Jung, Min Young Kim, Yeon Sil Kim, Jung-Young Shin, Jin-Hyoung Kang
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
BackgroundHypoxic tumors are known to be highly resistant to radiotherapy and cause poor prognosis in non-small cell lung cancer (NSCLC) patients. CKD-516, a novel vascular disrupting agent (VDA), mainly affects blood vessels in the central area of t
Autor:
Sang Ju Bae, Jung Young Shin, Jeong Oh Kim, Kyoung Hwa Son, Hyun Jung Min, Chan Kwon Jung, Tae-Jung Kim, Sook Whan Sung, Jin Hyoung Kang, Su Young Kim, Min Young Kim, Jae Kil Park
Publikováno v:
Surgical Oncology. 27:106-113
Background We screened resected tumor tissues from patients with lung cancer for EGFR mutations, ALK rearrangements, and rearranged during transfection (RET) gene variants (including RET rearrangements and the Kinesin Family Member 5B (KIF5B)-RET fus
Autor:
Kim, Min-Young, Jung-Young Shin, Jeong-Oh Kim, Kyoung-Hwa Son, Kim, Yeon Sil, Jung, Chan Kwon, Jin-Hyoung Kang
Additional file 2. Toxicity of low- or high-dose IR in BALB/c nude mice. (A) The shielding device was made of 4 mm thick lead. The anesthetized mice were fixed in a 50 mL tube and irradiated with a lead shield. (B) Tumor growth and (C) body weight ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24940c8a33d2963cecd39be247097072
Autor:
Kim, Min-Young, Jung-Young Shin, Jeong-Oh Kim, Kyoung-Hwa Son, Kim, Yeon Sil, Jung, Chan Kwon, Jin-Hyoung Kang
Additional file 1. Short-term and long-term drug administration schedules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716f8bb188fa0f0528f63e3dadcf62f7
Autor:
Kim, Min-Young, Jung-Young Shin, Jeong-Oh Kim, Kyoung-Hwa Son, Kim, Yeon Sil, Jung, Chan Kwon, Jin-Hyoung Kang
Additional file 3. IHC staining with HIF-1α, VEGF, Glut-1, and Ki-67 antibodies in all five treatment groups (72 h after the end of treatment). Mice were divided into five groups according to the dosing and treatment schedule: vehicle (PBS), IR alon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae1dfe1836d3971194e47a14ba47226
Autor:
Jin-Hyoung Kang, Jeong-Oh Kim, Chan-Kwon Jung, Jung-Young Shin, Kyoung-Hwa Son, Min Young Kim
Background: To evaluate the anti-tumor efficacy of CKD-516 in combined with irradiation (IR) and examine tumor necrosis, delayed tumor growth, and expression of molecules involved in hypoxia and angiogenesis. Methods : A xenograft mouse model of lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04d39a5a3d89f1237d18bcf443e5ba68
https://doi.org/10.21203/rs.2.19212/v1
https://doi.org/10.21203/rs.2.19212/v1
Autor:
Tae-Jung Kim, Jae Kil Park, Sang-Ju Bae, Sang Mi Ro, Chan Kwon Jung, Jeong-Oh Kim, Min Young Kim, Jung-Young Shin, Su Young Kim, Kyoung Hwa Son, Hyun-Jung Min, Sook-Whan Sung, Jin Hyoung Kang
Publikováno v:
Journal of Clinical Oncology. 35:e20610-e20610
e20610 Background: RET rearrangements have been identified in 1-2% of lung adenocarcinomas. The most common fusion is the KIF5B-RET, the function and roles of the RET fusion oncogene, and its downstream signaling molecules remain unclear. Methods: We