Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Kyoung-Hwa Lee"'
Autor:
Cho-Rong Lee, Jungyo Suh, Dongjun Jang, Bo-Yeong Jin, Jaeso Cho, Moses Lee, Hyungtai Sim, Minyong Kang, Jueun Lee, Ju Hyun Park, Kyoung-Hwa Lee, Geum-Sook Hwang, Kyung Chul Moon, Cheryn Song, Ja Hyeon Ku, Cheol Kwak, Hyeon Hoe Kim, Sung-Yup Cho, Murim Choi, Chang Wook Jeong
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 8, Pp 1807-1815 (2024)
Abstract TFE3-rearranged renal cell cancer (tRCC) is a rare form of RCC that involves chromosomal translocation of the Xp11.2 TFE3 gene. Despite its early onset and poor prognosis, the molecular mechanisms of the pathogenesis of tRCC remain elusive.
Externí odkaz:
https://doaj.org/article/bbfddcce0aa9476695825f4d115b7c2a
Autor:
SungEun Kim, Yubin Kim, JungHo Kong, Eunjee Kim, Jae Hyeok Choi, Hyeong Dong Yuk, HyeSun Lee, Hwa-Ryeon Kim, Kyoung-Hwa Lee, Minyong Kang, Jae-Seok Roe, Kyung Chul Moon, Sanguk Kim, Ja Hyeon Ku, Kunyoo Shin
Publikováno v:
eLife, Vol 8 (2019)
In bladder, loss of mammalian Sonic Hedgehog (Shh) accompanies progression to invasive urothelial carcinoma, but the molecular mechanisms underlying this cancer-initiating event are poorly defined. Here, we show that loss of Shh results from hypermet
Externí odkaz:
https://doaj.org/article/a9d59639fb0147d59313561a3cf97bd1
Autor:
Minyong Kang, Kyoung-Hwa Lee, Hye Sun Lee, Chang Wook Jeong, Ja Hyeon Ku, Hyeon Hoe Kim, Cheol Kwak
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184644 (2017)
We examined the anti-cancer effects and molecular mechanism of simvastatin in human castration-resistant prostate cancer (CRPC) cells, particularly focused on LIN28B and its target molecule, let-7 microRNA (miRNA) among the various target genes of NF
Externí odkaz:
https://doaj.org/article/94ac1d3a53404581b32a34df38c6b90c
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7451 (2009)
BACKGROUND:The enhancement of cell motility is a critical event during tumor cell spreading. Since myosin light chain kinase (MLCK) regulates cell behavior, it is regarded as a promising target in terms of preventing tumor invasion and metastasis. Si
Externí odkaz:
https://doaj.org/article/51b716d31dde44b7b2078b3d0b587795
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 55, Iss 5, Pp 812-819 (2022)
Background: Cytomegalovirus (CMV) can cause tissue-invasive diseases in various organs after primary infection or through reactivation of latent-to-lytic switch over a lifetime. The number of individuals who are at risk of CMV diseases, such as elder
Externí odkaz:
https://doaj.org/article/452da47cbedd437794e879d90c01230d
Autor:
Beomki Lee, Jae-Hoon Ko, Kyoung Hwa Lee, Yong Chan Kim, Young Goo Song, Yoon Soo Park, Yae Jee Baek, Jin Young Ahn, Jun Yong Choi, Kyoung-Ho Song, Eu Suk Kim, Seongman Bae, Sung-Han Kim, Hye Won Jeong, Shin-Woo Kim, Ki Tae Kwon, Su-Hwan Kim, Hyeonji Jeong, Byoungguk Kim, Sung Soon Kim, Won Suk Choi, Kyong Ran Peck, Eun-Suk Kang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Estimating neutralizing activity in vaccinees is crucial for predicting the protective effect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As the plaque reduction neutralization test (PRNT) requires a biosafety level
Externí odkaz:
https://doaj.org/article/ebe1df59013040a8af72fb98c1162658
Autor:
Hyuk Sang Kwon, Kee Ho Song, Jae Myung Yu, Dong Sun Kim, Ho Sang Shon, Kyu Jeung Ahn, Sung Hee Choi, Seung Hyun Ko, Won Kim, Kyoung Hwa Lee, Il Seong Nam-Goong, Tae Sun Park
Publikováno v:
Journal of Obesity & Metabolic Syndrome, Vol 30, Iss 3, Pp 261-270 (2021)
Background : This study aimed to evaluate cardiovascular risk in subjects with pre-diabetes and diabetes in Korea. Methods : In this pan-Korean, non-interventional, cross-sectional study, data were collected from medical records of 10 hospitals betwe
Externí odkaz:
https://doaj.org/article/71c73faf95124f0bb7a8bbb9964163f9
Autor:
Eliel Nham, Jae-Hoon Ko, Kyoung-Ho Song, Ju-Yeon Choi, Eu Suk Kim, Hye-Jin Kim, Byoungguk Kim, Hee-Young Lim, Kyung-Chang Kim, Hee-Chang Jang, Kyoung Hwa Lee, Young Goo Song, Yae Jee Baek, Jin Young Ahn, Jun Yong Choi, Yong Chan Kim, Yoon Soo Park, Won Suk Choi, Seongman Bae, Sung-Han Kim, Eun-Suk Kang, Hye Won Jeong, Shin-Woo Kim, Ki Tae Kwon, Sung Soon Kim, Kyong Ran Peck
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionDespite vaccine development, the COVID-19 pandemic is ongoing due to immunity-escaping variants of concern (VOCs). Estimations of vaccine-induced protective immunity against VOCs are essential for setting proper COVID-19 vaccination polic
Externí odkaz:
https://doaj.org/article/c4cb6849d1444a94a1b042cf18d19273
Autor:
Kyoung Hwa Lee, Seul Gi Yoo, Yonggeun Cho, Da Eun Kwon, Yeonju La, Sang Hoon Han, Myoung Soo Kim, Jin Sub Choi, Soon Il Kim, Yu Seun Kim, Yoo Hong Min, June-Won Cheong, Jin Seok Kim, Yong Goo Song
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 2, Pp 253-260 (2021)
Background/Purpose: Transplant recipients are vulnerable to life-threatening community-acquired respiratory viruses (CA-RVs) infection (CA-RVI). Even if non-transplant critically ill patients in intensive care unit (ICU) have serious CA-RVI, comparis
Externí odkaz:
https://doaj.org/article/df62bf6d5eaf45719fa125f32aab3a1a
Autor:
Jin Young Ahn, MD, Jeongsoo Lee, MD, You Suk Suh, PhD, Young Goo Song, ProfMD, Yoon-Jeong Choi, MS, Kyoung Hwa Lee, MD, Sang Hwan Seo, PhD, Manki Song, PhD, Jong-Won Oh, ProfPhD, Minwoo Kim, PhD, Han-Yeong Seo, BS, Jeong-Eun Kwak, PhD, Jin Won Youn, PhD, Jung Won Woo, PhD, Eui-Cheol Shin, ProfMD, Young Chul Sung, PhD, Su-Hyung Park, PhD, Jun Yong Choi, ProfMD
Publikováno v:
The Lancet Microbe, Vol 3, Iss 3, Pp e173-e183 (2022)
Summary: Background: We assessed the safety and immunogenicity of two recombinant DNA vaccines for COVID-19: GX-19 containing plasmid DNA encoding the SARS-CoV-2 spike protein, and GX-19N containing plasmid DNA encoding the SARS-CoV-2 receptor-bindin
Externí odkaz:
https://doaj.org/article/2d519caa8a64483a95491cb788fbffe1