Výsledky vyhledávání - "Kyoung Jin Lee"

Akademický článek

Mobilization of monocytic myeloid-derived suppressor cells is regulated by PTH1R activation in bone marrow stromal cells

Autor: Eun Jung Lee, Kyoung Jin Lee, Seungpil Jung, Kyong Hwa Park, Serk In Park

Publikováno v: Bone Research, Vol 11, Iss 1, Pp 1-14 (2023)

Abstract Myeloid-derived suppressor cells (MDSCs) are bone marrow (BM)-derived immunosuppressive cells in the tumor microenvironment, but the mechanism of MDSC mobilization from the BM remains unclear. We investigated how BM stromal cell activation b

Externí odkaz: https://doaj.org/article/6f94160c052e4bddb514d194acb07d2c

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Akademický článek

TCTP protein degradation by targeting mTORC1 and signaling through S6K, Akt, and Plk1 sensitizes lung cancer cells to DNA-damaging drugs

Autor: Mini Jeong, Mi Hyeon Jeong, Jung Eun Kim, Serin Cho, Kyoung Jin Lee, Serkin Park, Jeongwon Sohn, Yun Gyu Park

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)

Abstract Translationally controlled tumor protein (TCTP) is expressed in many tissues, particularly in human tumors. It plays a role in malignant transformation, apoptosis prevention, and DNA damage repair. The signaling mechanisms underlying TCTP re

Externí odkaz: https://doaj.org/article/08ad8eb1d4be49fe9198e6f52ee940a5

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Akademický článek

mTOR inhibition as a novel gene therapeutic strategy for diabetic retinopathy.

Autor: Steven Hyun Seung Lee, Joo Yong Lee, Jun-Sub Choi, Hee Jong Kim, Jin Kim, Seho Cha, Kyoung Jin Lee, Ha-Na Woo, Keerang Park, Heuiran Lee

Publikováno v: PLoS ONE, Vol 17, Iss 6, p e0269951 (2022)

In addition to laser photocoagulation, therapeutic interventions for diabetic retinopathy (DR) have heretofore consisted of anti-VEGF drugs, which, besides drawbacks inherent to the treatments themselves, are limited in scope and may not fully addres

Externí odkaz: https://doaj.org/article/e164b88d9f354d678fd705643f2be3cd

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Akademický článek

Real-time monitoring of oncolytic VSV properties in a novel in vitro microphysiological system containing 3D multicellular tumor spheroids.

Autor: Kyoung Jin Lee, Sang Woo Lee, Ha-Na Woo, Hae Mi Cho, Dae Bong Yu, Soo Yeon Jeong, Chul Hyun Joo, Gi Seok Jeong, Heuiran Lee

Publikováno v: PLoS ONE, Vol 15, Iss 7, p e0235356 (2020)

As a new class of cancer therapeutic agents, oncolytic viruses (OVs) have gained much attention not only due to their ability to selectively replicate in and lyse tumor cells, but also for their potential to stimulate antitumor immune responses. As a

Externí odkaz: https://doaj.org/article/99380ad0633044918f0c160fc00b4cd4

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Akademický článek

Usefulness of neutrophil gelatinase-associated lipocalin(NGAL) to confirm subclinical acute kidney injury and renal prognosis in patients following surgery

Autor: Se Jun Park, Hoseok Koo, Kyoung Jin Lee, Seo Hyun Kim, Seo Young Yun, Seunghyup Kim, Dong Hee Whang, Shin Young Joo, Byungmo Lee, HoJun Chin, Sihyung Park

Publikováno v: Kosin Medical Journal, Vol 32, Iss 2, Pp 212-220 (2017)

ObjectivesThe neutrophil gelatinase-associated lipocalin (NGAL) level following non cardiac surgery is useful for predicting acute kidney damage. However, there is insufficient conclusive evidence as to whether NGAL can be used to predict subclinical

Externí odkaz: https://doaj.org/article/8aaff5d117da43898694df6257260a33

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Akademický článek

Gene expression analysis of the microdissected trophoblast layer of human placenta after the spontaneous onset of labor.

Autor: Soo Hyun Kim, Sung Han Shim, Se Ra Sung, Kyung A Lee, Jung Yun Shim, Dong Hyun Cha, Kyoung Jin Lee

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77648 (2013)

BACKGROUND:Despite increasing evidence that human parturition is associated with alteration in gene expression in the uteroplacental unit, the precise mechanisms that elicit spontaneous term labor in humans remain unknown. Our goal in this study was

Externí odkaz: https://doaj.org/article/bca9563e21724a11903e1f92a97ec2c4

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