Zobrazeno 1 - 10
of 716
pro vyhledávání: '"Kyoung‐Mee Kim"'
Autor:
Soomin Ahn, Yoonjin Kwak, Gui Young Kwon, Kyoung-Mee Kim, Moonsik Kim, Hyunki Kim, Young Soo Park, Hyeon Jeong Oh, Kyoungyul Lee, Sung Hak Lee, Hye Seung Lee
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 58, Iss 3, Pp 103-116 (2024)
Nivolumab plus chemotherapy in the first-line setting has demonstrated clinical efficacy in patients with human epidermal growth factor receptor 2–negative advanced or metastatic gastric cancer, and is currently indicated as a standard treatment. P
Externí odkaz:
https://doaj.org/article/e1be02dd04134d55b078307f74344ab0
Autor:
Minkyue Shin, Soomin Ahn, Jaeyun Jung, Sujin Hyung, Kyoung‐Mee Kim, Seung Tae Kim, Won Ki Kang, Jeeyun Lee
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18633-18642 (2023)
Abstract Background Programmed death‐ligand 1 (PD‐L1) is an important screening biomarker to select patients with gastric cancer (GC) for optimized treatment, including immune checkpoint inhibitors (ICI). Methods In this single‐institution retr
Externí odkaz:
https://doaj.org/article/2f4db81ffe484be39b28ef6bda3c7a30
Publikováno v:
Cancer Medicine, Vol 12, Iss 11, Pp 12438-12451 (2023)
Abstract Background TP53 is the most commonly mutated gene across all cancer types. R175H mutation was considered structural mutation where the mutation causes misfolding of the protein and leads to a significant conformational alterations within p53
Externí odkaz:
https://doaj.org/article/8c44056f1eff4fa99292bf8f7bda024c
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 57, Iss 2, Pp 113-122 (2023)
Background Gallbladder cancer (GBC) is usually detected in advanced stages with a low 5-year survival rate. Delta-like ligand 4 (DLL4), vascular endothelial growth factor (VEGF), and hypoxia-inducible factor-2alpha (HIF2α) have been studied for thei
Externí odkaz:
https://doaj.org/article/007761423497425680dee7b6fed4a9da
Autor:
Young Soo Park, Myeong-Cherl Kook, Baek-hui Kim, Hye Seung Lee, Dong-Wook Kang, Mi-Jin Gu, Ok Ran Shin, Younghee Choi, Wonae Lee, Hyunki Kim, In Hye Song, Kyoung-Mee Kim, Hee Sung Kim, Guhyun Kang, Do Youn Park, So-Young Jin, Joon Mee Kim, Yoon Jung Choi, Hee Kyung Chang, Soomin Ahn, Mee Soo Chang, Song-Hee Han, Yoonjin Kwak, An Na Seo, Sung Hak Lee, Mee-Yon Cho
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 57, Iss 1, Pp 1-27 (2023)
The first edition of ‘A Standardized Pathology Report for Gastric Cancer’ was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago. Since then, significant advances have been mad
Externí odkaz:
https://doaj.org/article/28c9b54dfd1c4587b6cf9cf29e9e5170
Autor:
Sung Hee Lim, Jaeyun Jung, Jung Young Hong, Seung Tae Kim, Se Hoon Park, Joon Oh Park, Kyoung-Mee Kim, Jeeyun Lee
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3264 (2023)
Purpose: Therapeutic targeting of RAF1 is a promising cancer treatment, but the relationship between clinical features and RAF1 aberrations in terms of the MAPK signaling pathway is poorly understood in various solid tumors. Methods: Between October
Externí odkaz:
https://doaj.org/article/9802d46e123e4ee38b6fc134ba6d3c77
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3172 (2023)
Background: c-mesenchymal epithelial transition factor receptor (c-MET) and fibroblast growth factor receptor 2 (FGFR2) amplification have been identified as factors associated with advanced stage and poor prognosis in gastric cancer (GC). While they
Externí odkaz:
https://doaj.org/article/dcc1ffdb766c40619bcec8d0fd364a99
Autor:
Ji-Yeon Kim, Jeehyun Kim, Eun Yoon Cho, Yeon Hee Park, Jin Seok Ahn, Kyoung-Mee Kim, Young-Hyuck Im
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionImmune checkpoint inhibitor (ICI) is one of the standard treatment strategies in triple negative breast cancer (TNBC). However, the benefit of ICI with chemotherapy is limited in metastatic TNBC. In this study, we evaluated the effect of
Externí odkaz:
https://doaj.org/article/25f16b17854a49a683f704665485cc99
Autor:
So Young Kang, Deok Geun Kim, Hyunjin Kim, Yoon Ah Cho, Sang Yun Ha, Ghee Young Kwon, Kee-Taek Jang, Kyoung-Mee Kim
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-10 (2022)
Abstract Background Mutations in the telomerase reverse transcriptase (TERT) promoter region have been proposed as novel mechanisms for the transcriptional activation of telomerase. Two recurrent mutations in the TERT promoter, C228T and C250T, are p
Externí odkaz:
https://doaj.org/article/6732b5db0fa54118b8e97dd30cc5be89
Autor:
Jihoon Ko, Jaeyun Jung, Seung Tae Kim, Jung Yong Hong, Sehhoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Soomin Ahn, Kyoung-Mee Kim, Won Ki Kang, Jeeyun Lee
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
Background: To aid in oncology drug development, we investigated MET proto-oncogene receptor tyrosine kinase gene aberrations in 2,239 oncology patients who underwent next-generation sequencing (NGS) in clinical practice.Materials and methods: From N
Externí odkaz:
https://doaj.org/article/8a77c40a11f6496c8c69c8e9d5711c38