Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kyosuke Kazama"'
Autor:
Chen Zhang, Zhi-Fu Guo, Wennan Liu, Kyosuke Kazama, Louis Hu, Xiaobo Sun, Lu Wang, Hyoungjoo Lee, Lin Lu, Xiao-Feng Yang, Ross Summer, Jianxin Sun
Publikováno v:
eLife, Vol 12 (2023)
Proinflammatory agonists provoke the expression of cell surface adhesion molecules on endothelium in order to facilitate leukocyte infiltration into tissues. Rigorous control over this process is important to prevent unwanted inflammation and organ d
Externí odkaz:
https://doaj.org/article/e958c1a53c564fa4a355a2ae50dfb793
Autor:
Qing Ye, Jian Zhang, Chen Zhang, Bing Yi, Kyosuke Kazama, Wennan Liu, Xiaobo Sun, Yan Liu, Jianxin Sun
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
Arginine methylation mediated by protein arginine methyltransferases (PRMTs) has been shown to be an important posttranslational mechanism involved in various biological processes. Herein, we sought to investigate whether PRMT5, a major type II enzym
Externí odkaz:
https://doaj.org/article/1cf00ada2be54b82a8ed4a4d1e860ef2
Autor:
Guanxin Zhang, Qing Qin, Chen Zhang, Xiaobo Sun, Kyosuke Kazama, Bing Yi, Fang Cheng, Zhi-Fu Guo, Jianxin Sun
Publikováno v:
Circulation Research. 132:306-319
Background: NDRG-1 (N-myc downstream-regulated gene 1) is a member of NDRG family that plays essential roles in cell differentiation, proliferation, and stress responses. Although the expression of NDRG1 is regulated by fluid shear stress, its roles
Autor:
Chen Zhang, Zhi-Fu Guo, Wennan Liu, Kyosuke Kazama, Louis Hu, Xiaobo Sun, Lu Wang, Hyoungjoo Lee, Lin Lu, Xiao-Feng Yang, Ross Summer, Jianxin Sun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cf2e04f2fc0fd390c6b76ac35e7e50f
https://doi.org/10.7554/elife.85754.sa2
https://doi.org/10.7554/elife.85754.sa2
Autor:
Chen Zhang, Zhi-Fu Guo, Bing Yi, Kyosuke Kazama, Wennan Liu, Xiaobo Sun, Lu Wang, Xiao-Feng Yang, Ross Summer, Jianxin Sun
As a repair enzyme, protein L-isoaspartyl O-methyltransferase (PIMT) methylates and converts isoaspartyl residues (isoAsp) back to conventional forms to avoid protein damage during aging and stress responses. This study aims to investigate the pathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2676c1a1ea7b75010d38a39b2a7a76c
https://doi.org/10.1101/2022.01.25.477656
https://doi.org/10.1101/2022.01.25.477656
Autor:
Wennan Liu, Ru Ding, Deepak A. Deshpande, Xiaobo Sun, Xinyun Xu, Jianxin Sun, Kyosuke Kazama, Chun Liang, Bing Yi
Publikováno v:
Am J Respir Cell Mol Biol
American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology
Inflammasomes are intracellular multiprotein complexes that help trigger and maintain the inflammatory response as part of the innate immune system. Recently, it has been increasingly recognized that aberrant inflammasome activation is critically inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd383cd20abce19092788ed74673383
https://europepmc.org/articles/PMC8485996/
https://europepmc.org/articles/PMC8485996/
Autor:
Ru Ding, Xiaobo Sun, Bing Yi, Wennan Liu, Kyosuke Kazama, Xinyun Xu, Deshpande, Deepak A., Chun Liang, Jianxin Sun
Publikováno v:
American Journal of Respiratory Cell & Molecular Biology; Sep2021, Vol. 65 Issue 3, p288-299, 12p
Autor:
Hongyu Wang, Jian Zhang, Huijuan Yao, Bing Yi, Deepak A. Deshpande, Kyosuke Kazama, Yan Liu, Jianxin Sun
Abnormal airway smooth muscle cell (ASMC) proliferation and migration contribute significantly to increased ASM mass associated with asthma. MicroRNA (miR)-638 is a primate-specific miRNA that plays important roles in development, DNA damage repair,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdceaa13d1d9e739c3e0a8be7f82399
https://europepmc.org/articles/PMC6202131/
https://europepmc.org/articles/PMC6202131/
Autor:
Muneyoshi Okada, Hidemizu Kunimoto, Kyosuke Kazama, Mizuho Takai, Hideyuki Yamawaki, Mayuko Oda
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H1017-H1028
Blood chemerin concentration shows positive correlation not only with body mass index and serum triglyceride level but also with systolic blood pressure. While it seems likely that chemerin influences vascular smooth muscle cell (SMC) proliferation a
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 308:H1298-H1305
Pulmonary arterial (PA) hypertension (PAH) is a progressive and lethal disease that is caused by increased vascular contractile reactivity and structural remodeling. These changes contribute to increasing pulmonary peripheral vascular resistance, fin