Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kyosuke Asakawa"'
Autor:
Makoto Takeo, Kyosuke Asakawa, Koh-ei Toyoshima, Miho Ogawa, JingJing Tong, Tarou Irié, Masayuki Yanagisawa, Akio Sato, Takashi Tsuji
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract In mammals, organ induction occurs only during embryonic development except for hair follicles (HFs). However, HF-resident epithelial stem cells (HFSCs), which are responsible for repetitive HF regeneration, are not fully characterized. Here
Externí odkaz:
https://doaj.org/article/4c5bd77a700f4c5c80c1af47d2d30279
Autor:
Masayuki Yanagisawa, Miho Ogawa, Koh-ei Toyoshima, Kyosuke Asakawa, JingJing Tong, Akio Sato, Takashi Tsuji, Makoto Takeo, Tarou Irié
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
In mammals, organ induction occurs only during embryonic development except for hair follicles (HFs). However, HF-resident epithelial stem cells (HFSCs), which are responsible for repetitive HF regeneration, are not fully characterized. Here, we esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eba7f855ffb4932dbaeaf94c84a2bce
https://doaj.org/article/4c5bd77a700f4c5c80c1af47d2d30279
https://doaj.org/article/4c5bd77a700f4c5c80c1af47d2d30279
Autor:
Daisuke Nanba, Koji Sayama, Hiroyuki Matsumura, Kyosuke Asakawa, Fujio Toki, Emi K. Nishimura, Kyoichi Matsuzaki, Hiroshi Toki, Ken Shiraishi
Publikováno v:
Journal of Cell Biology. 220
Skin regenerative capacity declines with age, but the underlying mechanisms are largely unknown. Here we demonstrate a functional link between epidermal growth factor receptor (EGFR) signaling and type XVII collagen (COL17A1) proteolysis on age-assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431dc89c6032956b3c6f9d48f64bbaa7
https://doi.org/10.1083/jcb.202012073
https://doi.org/10.1083/jcb.202012073
Autor:
Hiroyuki Matsumura, Adèle De Arcangelis, Emi K. Nishimura, Aki Takada, Tomoki Kato, Daisuke Nanba, Hironobu Morinaga, Kyosuke Asakawa, Shizuko Ichinose, Takeshi Namiki, Elisabeth Geroges-Labouesse, Nan Liu, Yasuaki Mohri
Publikováno v:
Nature. 568:344-350
Stem cells underlie tissue homeostasis, but their dynamics during ageing—and the relevance of these dynamics to organ ageing—remain unknown. Here we report that the expression of the hemidesmosome component collagen XVII (COL17A1) by epidermal st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a79db9120f9dcd4f46d3e4ab0365049d
https://doi.org/10.1038/s41586-019-1085-7
https://doi.org/10.1038/s41586-019-1085-7
Autor:
Tomoki Kato, Nan Liu, Hironobu Morinaga, Kyosuke Asakawa, Taichi Muraguchi, Yuko Muroyama, Mariko Shimokawa, Hiroyuki Matsumura, Yuriko Nishimori, Li Jing Tan, Motoshi Hayano, David A. Sinclair, Yasuaki Mohri, Emi K. Nishimura
Publikováno v:
Developmental cell. 56(24)
Maintaining genomic integrity and stability is crucial for life; yet, no tissue-driven mechanism that robustly safeguards the epithelial genome has been discovered. Epidermal stem cells (EpiSCs) continuously replenish the stratified layers of keratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781fd072e0b062b561b285ab9b1b96c9
https://pubmed.ncbi.nlm.nih.gov/34932945
https://pubmed.ncbi.nlm.nih.gov/34932945
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1597
Hair follicles develop from the ectoderm in embryos and cyclically regenerate using proper spatiotemporal signaling molecules, which are conserved in organogenesis during adulthood. Previously, we demonstrated that bioengineered hair follicle germs c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb63565c7008f0e94db3829c4d1d33c8
https://pubmed.ncbi.nlm.nih.gov/28361314
https://pubmed.ncbi.nlm.nih.gov/28361314
Publikováno v:
Methods in Molecular Biology ISBN: 9781493969470
Hair follicles develop from the ectoderm in embryos and cyclically regenerate using proper spatiotemporal signaling molecules, which are conserved in organogenesis during adulthood. Previously, we demonstrated that bioengineered hair follicle germs c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10137c9a68645aa99e5abd21f37dcbeb
https://doi.org/10.1007/978-1-4939-6949-4_9
https://doi.org/10.1007/978-1-4939-6949-4_9
Autor:
Daisuke Nanba, Hironobu Morinaga, A.D. Arcangelis, Emi K. Nishimura, Aki Takada, E. Georges-Labouesse, Yasuaki Mohri, Kyosuke Asakawa, Nan Liu, Hiroyuki Matsumura, Takeshi Namiki, Shizuko Ichinose, Tomoki Kato
Publikováno v:
Journal of Investigative Dermatology. 139:S313
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56b5f23aeb4696b338c1734297a7f255
https://doi.org/10.1016/j.jid.2019.07.576
https://doi.org/10.1016/j.jid.2019.07.576
Autor:
Takashi Tsuji, Ayako Iwadate, Hirofumi Tobe, Akio Sato, Kyosuke Asakawa, Hiroshi Toki, Koh-ei Toyoshima, Naoko Ishibashi, Akira Takeda, Tatsuya Kanayama
Publikováno v:
The Journal of Dermatology. 39:682-687
The autologous transplantation of hair follicles that have been separated into single follicular units is an accepted treatment for androgenetic alopecia. Recent studies demonstrate that the multiple stem cell populations and surrounding cutaneous ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b520279b10ed73b36e938c2726a8d86d
https://doi.org/10.1111/j.1346-8138.2012.01505.x
https://doi.org/10.1111/j.1346-8138.2012.01505.x
Bioengineering a 3D integumentary organ system from iPS cells using an in vivo transplantation model
Autor:
Kyosuke Asakawa, Ayaka Sugawara, Toshihiro Yoshitake, Miho Ogawa, Akio Sato, Takashi Tsuji, Ryohei Minamide, Akira Takeda, Hiroshi Egusa, Akitoshi Kashiwakura, Kei Sakakibara, Koh ei Toyoshima, Masamitsu Oshima, Junko Ishimaru, Kentaro Ishida, Ryoji Takagi
Publikováno v:
Science Advances
A novel method is used to develop a functional 3D integumentary organ system, including appendage organs from iPS cells.
The integumentary organ system is a complex system that plays important roles in waterproofing, cushioning, protecting deepe
The integumentary organ system is a complex system that plays important roles in waterproofing, cushioning, protecting deepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3a4549c3b653037dd51f9a37e62d0e
https://pubmed.ncbi.nlm.nih.gov/27051874
https://pubmed.ncbi.nlm.nih.gov/27051874