Zobrazeno 1 - 10
of 670
pro vyhledávání: '"Kyoo A. Lee"'
Autor:
Bon-Kwan Koo, Eun-Ji Choi, Ju Hyun Moon, Ji Yun Kim, Hyunkyung Park, Han-Seung Park, Yunsuk Choi, Jung-Hee Lee, Kyoo-Hyung Lee, Eun Kyung Choi, Eunji Kim, Je-Hwan Lee, Eun-Hye Hur
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/ee392e65b396445a8540066bbd673738
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 401-416 (2024)
Lamin A/C, a core component of the nuclear lamina, forms a mesh-like structure beneath the inner nuclear membrane. While its structural role is well-studied, its involvement in DNA metabolism remains unclear. We conducted sequential protein fractiona
Externí odkaz:
https://doaj.org/article/252959cfcbaf45b6943abeaefa027f3e
Autor:
Sangin Kim, Yeongjae Kim, Youyoung Kim, Suhyeon Yoon, Kyoo-Young Lee, Yoonsung Lee, Sukhyun Kang, Kyungjae Myung, Chang-Kyu Oh
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285337 (2023)
Proliferating cell nuclear antigen (PCNA) is a maestro of DNA replication. PCNA forms a homotrimer and interacts with various proteins, such as DNA polymerases, DNA ligase I (LIG1), and flap endonuclease 1 (FEN1) for faithful DNA replication. Here, w
Externí odkaz:
https://doaj.org/article/e652c86ea5074c2caa1aada76b207e76
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Proliferating cell nuclear antigen (PCNA) plays a critical role as a processivity clamp for eukaryotic DNA polymerases and a binding platform for many DNA replication and repair proteins. The enzymatic activities of PCNA loading and unloadin
Externí odkaz:
https://doaj.org/article/3cdf03e11e53435abfa52199b12d0460
Autor:
Bon-Kwan Koo, Eun-Ji Choi, Eun-Hye Hur, Ju Hyun Moon, Ji Yun Kim, Han-Seung Park, Yunsuk Choi, Jung-Hee Lee, Kyoo-Hyung Lee, Eun Kyung Choi, Jinhwan Kim, Je-Hwan Lee
Publikováno v:
Heliyon, Vol 8, Iss 10, Pp e11004- (2022)
Acute myeloid leukemia (AML) is an aggressive blood cancer with a high rate of relapse associated with adverse survival outcomes, especially in elderly patients. An aberrant expression of cyclin dependent kinase 7 (CDK7) is associated with poor outco
Externí odkaz:
https://doaj.org/article/50efec5eace04c469ee2c2353e04ec1d
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
With aging, there is increased dysfunction of both innate and adaptive immune responses, which contributes to impaired immune responses to pathogens and greater mortality and morbidity. This age-related immune dysfunction is defined in general as imm
Externí odkaz:
https://doaj.org/article/c37f0f01cf894f8b8e8836d41da5e5ef
Autor:
Eun-Ji Choi, Tae Joon Jun, Han-Seung Park, Jung-Hee Lee, Kyoo-Hyung Lee, Young-Hak Kim, Young-Shin Lee, Young-Ah Kang, Mijin Jeon, Hyeran Kang, Jimin Woo, Je-Hwan Lee
Publikováno v:
JMIR Medical Informatics, Vol 10, Iss 3, p e32313 (2022)
BackgroundScoring systems developed for predicting survival after allogeneic hematopoietic cell transplantation (HCT) show suboptimal prediction power, and various factors affect posttransplantation outcomes. ObjectiveA prediction model using a mach
Externí odkaz:
https://doaj.org/article/be0d87b8fc2c41e38f043861b24d585d
Autor:
Su Hyung Park, Nalae Kang, Eunho Song, Minwoo Wie, Eun A. Lee, Sunyoung Hwang, Deokjae Lee, Jae Sun Ra, In Bae Park, Jieun Park, Sukhyun Kang, Jun Hong Park, Sungchul Hohng, Kyoo-young Lee, Kyungjae Myung
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
How the replisome machinery contributes to fork stability under replication stress is currently not clear. Here the authors reveal a role for ATAD5 in maintaining genome integrity during replication stress by promoting replication restart through RAD
Externí odkaz:
https://doaj.org/article/4ac4913c149c4dd78292e37f24a832b8
Autor:
Ri Jin, Kyoo-Seock Lee
Publikováno v:
Remote Sensing, Vol 14, Iss 22, p 5836 (2022)
Forest fires cause damage to property and the environment around the world every year. North Korea has suffered from fires every year. Fires may lead to temporary or permanent damage to forest ecosystems, long-term site degradation, and alteration of
Externí odkaz:
https://doaj.org/article/18ba08e66c5e453e949b444a7e8ebbd5
Autor:
Hyun Je Kang, Hyun Park, Eun Jin Yoo, Jun Ho Lee, Soo Youn Choi, Whaseon Lee-Kwon, Kyoo-young Lee, Jin-Hoe Hur, Jeong Kon Seo, Jae Sun Ra, Eun-A. Lee, Kyungjae Myung, Hyug Moo Kwon
Publikováno v:
iScience, Vol 19, Iss , Pp 177-190 (2019)
Summary: Polyubiquitination of proliferating cell nuclear antigen (PCNA) regulates the error-free template-switching mechanism for the bypass of DNA lesions during DNA replication. PCNA polyubiquitination is critical for the maintenance of genomic in
Externí odkaz:
https://doaj.org/article/14a94c35bac0452abc34bf283bd79d85