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Autor:
Hideji Itokawa, Mariko Katsuyama, Masuo Inoue, Koichi Takeya, George R. Pettit, Hiroshi Morita, Toshiaki Segawa, Nobuyo Nandachi, Hirofumi Hashima, Ayako Yukita, Yoshiaki Kamano, Ayano Kotake, Kyoko Saitou
Publikováno v:
Bioorganicmedicinal chemistry. 6(7)
The toad poison bufadienolides including natural and derivatized compounds were tested for their cytotoxic effects on primary liver carcinoma cells PLC/PRF/5 and their structure-cytotoxic activity relationships were studied. For this study, a ligand-