Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kyoko Oh-oka"'
Publikováno v:
Journal of immunology. 209(12):2313-2321
Psoriasis is a chronic inflammatory skin disease. IL-23 plays a critical role in its pathogenesis by inducing production of IL-17A from pathological Th17 cells and IL-17A–producing γδ T cells. However, the mechanisms regulating the IL-23/IL-17 ax
Autor:
Kyoko Oh-oka, Yuko Kojima, Koichiro Uchida, Kimiko Yoda, Kayoko Ishimaru, Shotaro Nakajima, Jun Hemmi, Hiroshi Kano, Yoshiaki Fujii-Kuriyama, Ryohei Katoh, Hiroyuki Ito, Atsuhito Nakao
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 1, Pp 135-151 (2017)
Background & Aims: Mesalamine is a first-line drug for treatment of inflammatory bowel diseases (IBD). However, its mechanisms are not fully understood. CD4+ Foxp3+ regulatory T cells (Tregs) play a potential role in suppressing IBD. This study deter
Externí odkaz:
https://doaj.org/article/fa32002dd88e4216a17dac4d9e5ca334
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 40:52-59
DNAM-1 is an activating immunoreceptor expressed on hematopoietic cells, including both CD4+ and CD8+ T cells, natural killer cells, and platelets. Since DNAM-1 is involved in the pathogenesis of various inflammatory diseases and cancers in humans as
Autor:
Yoko Aihara, Kyoko Oh-oka, Naoki Kondo, Jyoti Sharma, Narayan C. Shrestha, Kayoko Ishimaru, Mutsuko Hara, Zentaro Yamagata, Atsuhito Nakao
Publikováno v:
Allergology International, Vol 63, Iss 2, Pp 283-285 (2014)
Externí odkaz:
https://doaj.org/article/1a0e17b8aa76489b80535004b869a555
Autor:
Yui Okada, Kyoko Oh-oka, Yuki Nakamura, Kayoko Ishimaru, Shuji Matsuoka, Ko Okumura, Hideoki Ogawa, Masashi Hisamoto, Tohru Okuda, Atsuhito Nakao
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44338 (2012)
BACKGROUND: Resveratrol is a bioactive polyphenol enriched in red wine that exhibits many beneficial health effects via multiple mechanisms. However, it is unclear whether resveratrol is beneficial for the prevention of food allergy. This study inves
Externí odkaz:
https://doaj.org/article/2bc9828060b9443e8d555d5ce8f196c6
Autor:
Shotaro Nakajima, Atsuhito Nakao, Kyoko Oh-oka, Yuki Nakamura, Ha Pham Thu Le, Kayoko Ishimaru
Publikováno v:
Biochemical and Biophysical Research Communications. 490:290-295
Interleukin-17–producing CD4+ T helper (Th17) cells are a key immune lineage that protects against bacterial and fungal infections at mucosal surfaces. At steady state, Th17 cells are abundant in the small intestinal mucosa of mice. There are sever
Autor:
Hiroyuki Ito, Shotaro Nakajima, Jun Hemmi, Yoshiaki Fujii-Kuriyama, Yuko Kojima, Ryohei Katoh, Kyoko Oh-oka, Kimiko Yoda, Hiroshi Kano, Kayoko Ishimaru, Koichiro Uchida, Atsuhito Nakao
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 1, Pp 135-151 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Mesalamine is a first-line drug for treatment of inflammatory bowel diseases (IBD). However, its mechanisms are not fully understood. CD4+ Foxp3+ regulatory T cells (Tregs) play a potential role in suppressing IBD. This study determ
Autor:
Shotaro Nakajima, Katsue Suzuki-Inoue, Koji Kono, Atsuhito Nakao, Yuki Nakamura, Anna Kobayashi, Kayoko Ishimaru, Guannan Yu, Kyoko Oh-oka
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Interleukin-33 (IL-33)/ST2–mediated mast cell activation plays important roles in the pathophysiology of allergic diseases. Hence, pharmacologically targeting the IL-33/ST2 pathway in mast cells could help to treat such diseases. We found that resv
Autor:
Zentaro Yamagata, Kohta Suzuki, Kyoko Oh-oka, Akiko Nagai, Naoki Kondo, Taichiro Tanaka, Atsuhito Nakao, Miri Sato, Kayoko Ishimaru, Yuki Suda
Publikováno v:
Pediatric Allergy and Immunology. 22:853-861
Background: Cytokines in breast milk may play crucial roles in the beneficial effects of breastfeeding in protecting against allergic and infectious diseases in infants. In particular, breast milk-borne transforming growth factor-beta (TGF-b) has an
Autor:
Jyoti Sharma, Naoki Kondo, Narayan Shrestha, Kyoko Oh-oka, Mutsuko Hara, Atsuhito Nakao, Yoko Aihara, Kayoko Ishimaru, Zentaro Yamagata
Publikováno v:
Allergology International, Vol 63, Iss 2, Pp 283-285 (2014)