Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Kyoko MASUDA"'
Autor:
Alexis Vandenbon, Rin Mizuno, Riyo Konishi, Masaya Onishi, Kyoko Masuda, Yuka Kobayashi, Hiroshi Kawamoto, Ayako Suzuki, Chenfeng He, Yuki Nakamura, Kosuke Kawaguchi, Masakazu Toi, Masahito Shimizu, Yasuhito Tanaka, Yutaka Suzuki, Shinpei Kawaoka
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Spatial transcriptomics reveal how distant cancer affect gene expression and zonation in mouse liver in a manner that differs between biological pathways.
Externí odkaz:
https://doaj.org/article/48608d65ba534a52a3c3a5a77a96a0fd
Autor:
Koji Terada, Kenta Kondo, Hirohito Ishigaki, Ayaka Nagashima, Hiroki Satooka, Seiji Nagano, Kyoko Masuda, Teruhisa Kawamura, Takako Hirata, Kazumasa Ogasawara, Yasushi Itoh, Hiroshi Kawamoto, Yasutoshi Agata
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 77-86 (2022)
To develop effective adoptive cell transfer therapy using T cell receptor (TCR)-engineered T cells, it is critical to isolate tumor-reactive TCRs that have potent anti-tumor activity. In humans, tumor-infiltrating lymphocytes (TILs) have been reporte
Externí odkaz:
https://doaj.org/article/26e650926bb94137978f4db5a627454b
Autor:
Kyoko Masuda, Hiroshi Kawamoto
Publikováno v:
Inflammation and Regeneration, Vol 41, Iss 1, Pp 1-9 (2021)
Abstract In the regenerative medicine field, allogenic transplantation of regenerated tissues has been promoted because autologous transplantation setting is costly and time-consuming to prepare and therefore unsuitable for emergent treatment. To avo
Externí odkaz:
https://doaj.org/article/aa99cfccd2a64e699dbab051c562a779
Autor:
Takuya Maeda, Seiji Nagano, Soki Kashima, Koji Terada, Yasutoshi Agata, Hiroshi Ichise, Manami Ohtaka, Mahito Nakanishi, Fumihiro Fujiki, Haruo Sugiyama, Toshio Kitawaki, Norimitsu Kadowaki, Akifumi Takaori-Kondo, Kyoko Masuda, Hiroshi Kawamoto
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 250-260 (2020)
In the current adoptive T cell therapy, T cells from a patient are given back to that patient after ex vivo activation, expansion, or genetic manipulation. However, such strategy depends on the quality of the patient’s T cells, sometimes leading to
Externí odkaz:
https://doaj.org/article/e94f6375e43049b79591e27e60345c7a
Autor:
Seiji Nagano, Takuya Maeda, Hiroshi Ichise, Soki Kashima, Manami Ohtaka, Mahito Nakanishi, Toshio Kitawaki, Norimitsu Kadowaki, Akifumi Takaori-Kondo, Kyoko Masuda, Hiroshi Kawamoto
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 16, Iss , Pp 126-135 (2020)
Current adoptive T cell therapies conducted in an autologous setting are costly, time-consuming, and depend on the quality of the patient’s T cells, and thus it would be highly beneficial to develop an allogeneic strategy. To this aim, we have deve
Externí odkaz:
https://doaj.org/article/1149dc76f1b64229944bceb0a2222a6e
Autor:
Yuki Sato, Akiko Oguchi, Yuji Fukushima, Kyoko Masuda, Naoya Toriu, Keisuke Taniguchi, Takahisa Yoshikawa, Xiaotong Cui, Makiko Kondo, Takeshi Hosoi, Shota Komidori, Yoko Shimizu, Harumi Fujita, Li Jiang, Yingyi Kong, Takashi Yamanashi, Jun Seita, Takuya Yamamoto, Shinya Toyokuni, Yoko Hamazaki, Masakazu Hattori, Yasunobu Yoshikai, Peter Boor, Jürgen Floege, Hiroshi Kawamoto, Yasuhiro Murakawa, Nagahiro Minato, Motoko Yanagita
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 2 (2022)
Tertiary lymphoid tissues (TLTs) facilitate local T and B cell interactions in chronically inflamed organs. However, the cells and molecular pathways that govern TLT formation are poorly defined. Here, we identified TNF superfamily CD153/CD30 signali
Externí odkaz:
https://doaj.org/article/4e3ce5bb02bd4250838868a6955a71d3
Autor:
Miki Arai Hojo, Kyoko Masuda, Hiroaki Hojo, Yosuke Nagahata, Keiko Yasuda, Daiya Ohara, Yusuke Takeuchi, Keiji Hirota, Yutaka Suzuki, Hiroshi Kawamoto, Shinpei Kawaoka
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Autoreactive T cells are deleted in the thymus via thymic negative selection and Bim-mediated apoptosis. Here the authors identify a cis-acting enhancer, E BAB , that is essential for proper Bim expression and apoptosis induction, and show that E BAB
Externí odkaz:
https://doaj.org/article/a59967540154488a8bba0887e70baf97
Autor:
Soki Kashima, Takuya Maeda, Kyoko Masuda, Seiji Nagano, Takamitsu Inoue, Masashi Takeda, Yuka Kono, Takashi Kobayashi, Shigeyoshi Saito, Takahiro Higuchi, Hiroshi Ichise, Yuka Kobayashi, Keiko Iwaisako, Koji Terada, Yasutoshi Agata, Kazuyuki Numakura, Mitsuru Saito, Shintaro Narita, Masaki Yasukawa, Osamu Ogawa, Tomonori Habuchi, Hiroshi Kawamoto
Publikováno v:
iScience, Vol 23, Iss 4, Pp - (2020)
Summary: Current adoptive T cell therapies conducted in an autologous setting are costly, time consuming, and depend on the quality of the patient's T cells. To address these issues, we developed a strategy in which cytotoxic T lymphocytes (CTLs) are
Externí odkaz:
https://doaj.org/article/8642056a6e3e46368c7a690d7178da9a
Autor:
Hiroshi Ichise, Seiji Nagano, Takuya Maeda, Masaki Miyazaki, Yuki Miyazaki, Hiroto Kojima, Nobuyo Yawata, Makoto Yawata, Hidenori Tanaka, Hiroh Saji, Kyoko Masuda, Hiroshi Kawamoto
Publikováno v:
Stem Cell Reports, Vol 9, Iss 3, Pp 853-867 (2017)
HLA haplotype-homozygous (HLA-homo) induced pluripotent stem cells (iPSCs) are being prepared to be used for allogeneic transplantation of regenerated tissue into recipients carrying an identical haplotype in one of the alleles (HLA-hetero). However,
Externí odkaz:
https://doaj.org/article/55716d85db5e4dffa93d13d9157f0cc5
Autor:
Tomokatsu Ikawa, Kyoko Masuda, Mirelle J.A.J. Huijskens, Rumi Satoh, Kiyokazu Kakugawa, Yasutoshi Agata, Tomohiro Miyai, Wilfred T.V. Germeraad, Yoshimoto Katsura, Hiroshi Kawamoto
Publikováno v:
Stem Cell Reports, Vol 5, Iss 5, Pp 716-727 (2015)
Self-renewal potential and multipotency are hallmarks of a stem cell. It is generally accepted that acquisition of such stemness requires rejuvenation of somatic cells through reprogramming of their genetic and epigenetic status. We show here that a
Externí odkaz:
https://doaj.org/article/75165807deb44108b1dc967407f67658