Výsledky vyhledávání - "Kyoko Kubota"

A Novel Nutritional Index Serves as A Useful Prognostic Indicator in Cardiac Critical Patients Requiring Mechanical Circulatory Support

Autor: Asuka Minami-Takano, Atsushi Amano, Minako Shitara, Atsushi Kimura, Katsumi Miyauchi, Hiroyuki Daida, Kyoko Kubota, Hiroshi Iwata, Satoru Suwa, Masataka Sumiyoshi, Shinya Okazaki, Shota Osawa, Katsutoshi Miyosawa

Publikováno v: Nutrients
Volume 11
Issue 6
Nutrients, Vol 11, Iss 6, p 1420 (2019)

Background: A poor nutritional status has been gathering intense clinical interest recently as it has been suggested to associate with adverse outcomes in patients in the intensive care unit (ICU). However, there is still no established nutritional i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2db2faba0c0de04ec0bce4627ece5d

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Dysbindin engages in c-Jun N-terminal kinase activity and cytoskeletal organization

Autor: Taiichi Katayama, Masaya Tohyama, Masatoshi Takeda, Natsuko Kumamoto, Hironori Takamura, Shinsuke Matsuzaki, Hiroaki Okuda, Kyoko Kubota, Ryota Hashimoto, Tsuyoshi Hattori

Publikováno v: Biochemical and Biophysical Research Communications. 379:191-195

A number of reports have provided genetic evidence for an association between the DTNBP1 gene (coding dysbindin) and schizophrenia. In addition, sandy mice, which harbor a deletion in the DTNBP1 gene and lack dysbindin, display behavioral abnormaliti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fba3d9ac0040a3e0b1272bcb3736ae
https://doi.org/10.1016/j.bbrc.2008.12.017

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Tumor necrosis factor receptor-associated protein 1 regulates cell adhesion and synaptic morphology via modulation of N-cadherin expression

Autor: Masaya Tohyama, M Tatsumi, Asako Kosuga, Norio Ozaki, Natsuko Kumamoto, Masatoshi Takeda, Kiyoshi Inoue, Ryota Hashimoto, Kyoko Kubota, Hiroshi Kunugi, Kunitoshi Kamijima, Nakao Iwata

Publikováno v: Journal of neurochemistry. 110(2)

An increase in serum tumor necrosis factor-alpha (TNF-alpha) levels is closely related to the pathogenesis of major depression. However, the underlying molecular mechanism between this increase and impairment of brain function remains elusive. To bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2981838175ef4a62d67031017fc7e5a8
https://pubmed.ncbi.nlm.nih.gov/19490362

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A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

Autor: Yasunobu Okuma, Takashi Uehara, Ryosuke Takahashi, Akihisa Hata, Masayuki Kaneko, Kazuo Nagashima, Yasuko Orba, Karin Murahashi, Noboru Fujitani, Yasuyuki Nomura, Kyoko Kubota, Satoshi Matsumura, Tomohiro Omura

Publikováno v: Journal of neurochemistry. 99(6)

It has been proposed that in autosomal recessive juvenile parkinsonism (AR-JP), a ubiquitin ligase (E3) Parkin, which is involved in endoplasmic reticulum-associated degradation (ERAD), lacks E3 activity. The resulting accumulation of Parkin-associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351ad1a575271e1d57167fa91117fc2a
https://pubmed.ncbi.nlm.nih.gov/17059562

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Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress

Autor: Toru Hosoi, Masayuki Kaneko, Takashi Uehara, Yoshifumi Niinuma, Mami Sugai, Mai Uesugi, Kyoko Kubota, Yasunobu Okuma, Yasuyuki Nomura, Tomohiro Omura

Publikováno v: Journal of neurochemistry. 97(5)

Endoplasmic reticulum (ER) stress is defined as an accumulation of unfolded proteins in the endoplasmic reticulum. 4-phenylbutyrate (4-PBA) has been demonstrated to promote the normal trafficking of the DeltaF508 cystic fibrosis transmembrane conduct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c646122f43efd733119c77d975ef2af0
https://pubmed.ncbi.nlm.nih.gov/16539653

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DNA binding properties of DAPI (4',6-diamidino-2-phenylindole) analogs having an imidazoline ring or a tetrahydropyrimidine ring: groove-binding and intercalation

Autor: Kyoko Kubota, Seiji Tani, Yukio Kubota

Publikováno v: Nucleic acids symposium series. (44)

DAPI analogs containing an imidazoline ring or a tetrahydropyrimidine ring have been synthesized to study DNA binding properties. Spectroscopic (absorption, CD, flow dichroism and fluorescence) and viscosity measurements indicate that DAPI analogs in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3a7eb89e78ac535b92773b2c2ac431
https://pubmed.ncbi.nlm.nih.gov/12903264

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