Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kyoko Kakimoto"'
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87229 (2014)
N-acetyl-L-cysteine is known to act as a reactive oxygen species scavenger and used in clinical applications. Previous reports have shown that high-dose N-acetyl-L-cysteine treatment inhibits the expression of proinflammatory cytokines in activated m
Externí odkaz:
https://doaj.org/article/07bb4e8b89a94862acc454c4ab5e325a
Autor:
Kenjiro Bandow, Tetsuya Matsuguchi, Joji Kusuyama, Kyoko Kakimoto, Tomokazu Ohnishi, Takuro Kanekura, Mitsuhiro Hisadome
Publikováno v:
FEBS Letters. 590:3595-3605
Keratinocytes secrete vascular endothelial growth factor (VEGF) and angioregulatory chemokines during cutaneous wound healing. Hepatocyte growth factor (HGF) promotes skin re-epithelialization by increasing VEGF expression in keratinocytes. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8881827386cfdcf63cde9b2880770e
https://doi.org/10.1002/1873-3468.12452
https://doi.org/10.1002/1873-3468.12452
Autor:
Kyoko Kakimoto, Yasuyuki Fujii, Kenjiro Bandow, Tetsuya Matsuguchi, Joji Kusuyama, Juna Nakao, Tomokazu Ohnishi
Publikováno v:
Bone. 58:17-25
Previous reports have shown that osteoblasts are mechano-sensitive. Low-intensity pulsed ultrasound (LIPUS) induces osteoblast differentiation and is an established therapy for bone fracture. Here we have examined how LIPUS affects inflammatory respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893260067435a58ff329787587b03f9c
https://doi.org/10.1016/j.bone.2013.09.018
https://doi.org/10.1016/j.bone.2013.09.018
Autor:
Kenjiro Bandow, Tetsuya Matsuguchi, Mitsuo Shamoto, Joji Kusuyama, Tomokazu Ohnishi, Kyoko Kakimoto
Publikováno v:
FEBS Letters. 586:1540-1546
LPS signaling is mediated through MyD88-dependent and -independent pathways, activating NF-κB, MAP kinases and IRF3. Cot/Tpl2 is an essential upstream kinase in LPS-mediated activation of ERKs. Here we explore the roles of MyD88 and Cot/Tpl2 in LPS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67a5361cc2aea0c5ef3c11e8f8b70f7
https://doi.org/10.1016/j.febslet.2012.04.018
https://doi.org/10.1016/j.febslet.2012.04.018
Publikováno v:
Biochemical and Biophysical Research Communications. 402:1-6
Cot/Tpl2, a member of MAP kinase kinase kinase (MAPKKK), is indispensable for the ERK activation, as well as the production of TNF-α, IL-1β, IL-23, and PGE(2) in lipopolysaccharide (LPS)-stimulated macrophages. However, the expression and the funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5e6b3546bda34754bd7768524fe585
https://doi.org/10.1016/j.bbrc.2010.08.075
https://doi.org/10.1016/j.bbrc.2010.08.075
Autor:
Tipayaratn Musikacharoen, Kenjiro Bandow, Tetsuya Matsuguchi, Kyoko Kakimoto, Norika Chiba, Tomokazu Ohnishi
Publikováno v:
Journal of Physiology and Biochemistry. 66:47-53
We have previously reported that a serine/threonine protein kinase, Cot/Tpl2, is a negative regulator of Th1-type immunity through inhibiting IL-12 expression in antigen presenting cells (APCs) stimulated by Toll-like receptor (TLR) ligands. We here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616b0cff5e4c6942395b021d7d757f96
https://doi.org/10.1007/s13105-010-0007-9
https://doi.org/10.1007/s13105-010-0007-9
Autor:
Tomokazu Ohnishi, Tetsuya Matsuguchi, A. Okamoto, Kyoko Kakimoto, Kenjiro Bandow, Norika Chiba
Publikováno v:
Journal of Dental Research. 89:192-197
Periodontitis causes resorption of alveolar bone, in which RANKL induces osteoclastogenesis. The binding of lipopolysaccharide to Toll-like receptors causes phosphorylation of Cot/Tp12 to activate the MAPK cascade. Previous in vitro studies showed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a56f6e891dc956cee8589ade834ef57
https://doi.org/10.1177/0022034509353405
https://doi.org/10.1177/0022034509353405
Autor:
Atsuko Okamoto, Tomohiro Fukunaga, Tomokazu Ohnishi, Kyoko Kakimoto, Tetsuya Matsuguchi, Norika Chiba, Shouichi Miyawaki, Kenjiro Bandow, Aya Maeda
Publikováno v:
European Journal of Oral Sciences. 117:238-247
Orthodontic therapy is known to have an aggravating effect on the progression of destructive periodontitis if oral hygiene is not maintained. However, it is largely unknown how active periodontitis affects the velocity of orthodontic tooth movement.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3cd8ad2bf55ab22d0501c99e5aea109
https://doi.org/10.1111/j.1600-0722.2009.00625.x
https://doi.org/10.1111/j.1600-0722.2009.00625.x
Autor:
Tomokazu Ohnishi, Miho Machigashira, Kyoko Kakimoto, Tetsuya Matsuguchi, Takashi Matsuyama, Kenjiro Bandow
Publikováno v:
Journal of Periodontal Research. 44:43-51
Background and Objective: Alveolar bone loss is caused by a host response to periodontal pathogens, and its progression is often enhanced by systemic conditions such as insulin resistance.Alveolar bone dehiscence has been observed in KK-Ay mice, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2577dd842119edf5f3fb4bf28879a8ab
https://doi.org/10.1111/j.1600-0765.2007.01060.x
https://doi.org/10.1111/j.1600-0765.2007.01060.x
Autor:
Tomokazu Ohnishi, Hiroyasu Akatsu, Kenichi Ogawa, Tatsuo Yamada, T. Yamamoto, Yasushi Daikuhara, Masashi Nakajima, Kyoko Kakimoto, Yoshio Tsuboi
Publikováno v:
Acta Neurologica Scandinavica. 107:81-86
Background & Objective - Hepatocyte growth factor (HGF), also known as the scatter factor, is a potent mitogen for mature hepatocytes, and also has multifunctional effects on some cells in various organs. Recently, we have found expression and locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b81d9cc489e6c97c57cf9276f3733e38
https://doi.org/10.1034/j.1600-0404.2003.02089.x
https://doi.org/10.1034/j.1600-0404.2003.02089.x