Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kyoko Iwase"'
Publikováno v:
Diabetes Case Reports.
Interferon α (IFNα) has been reported to induce several autoimmune diseases, including autoimmune thyroiditis (AITD) and type 1 diabetes (T1D). In addition, co-occurrence of T1D and AITD is well known as one of the variants of the autoimmune polygl
Autor:
Arafumi Maeshima, Yoshitaka Oyamada, Kazuyuki Fujimoto, Takanori Asakura, Kyoko Iwase, Shuichi Yoshida, Rie Jo
Publikováno v:
Internal medicine (Tokyo, Japan). 54(23)
Small cell lung cancer (SCLC) causes paraneoplastic syndromes, such as diabetes mellitus, by eliciting the expression of various antibodies including anti-glutamate decarboxylase (GAD) antibody. A 62-year-old woman presented to our hospital with a 1-
Autor:
Toshihide Kawai, Junichiro Irie, Yoichi Oikawa, Akira Shimada, Hiroshi Itoh, Yoshiaki Okubo, Kyoko Iwase, Taro Maruyama, Hiroshi Hirose, Yasuhiko Kanazawa
Publikováno v:
Autoimmunity. 42:159-167
Some reports have shown that the cause of type 1 diabetes is associated with dysfunction of regulatory T cells (Tregs). The FOXP3/Scurfin gene is known to be a master gene of Tregs. Therefore, we tried to analyze the relation between the gene polymor
Autor:
Yasuo Oyama, Tomoko Tatsuishi, Aimi Kanada, Kyoko Iwase, Yumiko Nishimura, Masako Kobayashi, Jun-ya Yamaguchi, Kyoko Mishima
Publikováno v:
Toxicology. 211:179-186
Cremophor EL, a surfactant for pharmaceutical products, augments the cytotoxicity of hydrogen peroxide in rat thymocytes [Iwase, K., Oyama, Y., Tatsuishi, T., Yamaguchi1, J., Nishimura1, Y., Kanada, A., Kobayashi, M., Maemura, Y., Ishida, S., Okano,
Autor:
Tomoko Tatsuishi, Jun-ya Yamaguchi, Yasuo Oyama, Aimi Kanada, Yoshiro Okano, Kyoko Iwase, Yumiko Nishimura, Yuko Maemura, Masako Kobayashi, Shiro Ishida
Publikováno v:
Toxicology Letters. 154:143-148
The pharmaceutical uses of cremophor EL, a non-ionic surfactant, are similar to those of polysorbate 80. In our previous study, polysorbate 80 exerted some adverse actions on rat thymocytes under in vitro condition. Therefore, the effects of cremopho
Autor:
Koji Murao, Hiromi Nakao, Yasuo Oyama, Yasutaka Nishizaki, Hakaru Seo, Tomoko Tatsuishi, Kyoko Iwase, T Ueha-Ishibashi, Chisato Umebayashi
Publikováno v:
Toxicology. 195:77-84
The effect of thimerosal, an organomercurial preservative in vaccines, on cerebellar neurons dissociated from 2-week-old rats was compared with those of methylmercury using a flow cytometer with appropriate fluorescent dyes. Thimerosal and methylmerc
Autor:
Hayato Hikita, Norio Hayashi, Kyoko Iwase, Naoki Hiramatsu, Atsushi Hosui, Wei Li, Tatsuya Kanto, Satoshi Shimizu, Takuya Miyagi, Hisashi Ishida, Tomohide Tatsumi, Minoru Shigekawa, Tetsuo Takehara, Takahiro Kodama
Publikováno v:
Hepatology (Baltimore, Md.). 52(4)
Tumor cells are characterized by uncontrolled proliferation, often driven by activation of oncogenes, and apoptosis resistance. The oncogenic kinase inhibitor sorafenib can significantly prolong median survival of patients with advanced hepatocellula
Autor:
Yasuo Oyama, Jun-ya Yamaguchi, Yumiko Nishimura, Norikazu Miyoshi, Kyoko Iwase, Makoto Wada, Tomoko Tatsuishi
Publikováno v:
Environmental toxicology. 19(6)
Despite the growing use of organotellurium compounds in the chemical and biomedical fields, there has been no great concern about their toxicity until now. To test the possibility that diphenyl ditelluride (DPDT) and tellurium chloride (TeCl2), organ
Autor:
Yasuo Oyama, Aimi Kanada, Masako Kobayashi, Yumiko Nishimura, Seigo Hirama, Jun-ya Yamaguchi, Kyoko Iwase, Tomoko Tatsuishi
Publikováno v:
Toxicology. 207(1)
Effect of simultaneous application of polysorbate 80, a nonionic surfactant widely used in pharmaceutical products, and hydrogen peroxide on rat thymocytes was examined to see if polysorbate 80 increases the susceptibility to oxidative stress because
Autor:
Yasutaka Nishizaki, Seigo Hirama, Chisato Umebayashi, T Ueha-Ishibashi, Yasuo Oyama, Hiromi Nakao, Yoshiro Okano, Yumiko Nishimura, Tomoko Tatsuishi, Kyoko Iwase
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 18(5)
There is a concern on the part of public health community that adverse health consequences by thimerosal, a preservative in vaccines for infants, may occur among infants during immunization schedule. Therefore, the effect of thimerosal on cellular co