Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Kyoko Hotta"'
Autor:
Yoshinori Matsuwaki, Kota Wada, James L. Checkel, Linda M. Benson, Christopher B. Lawrence, Jens U. Ponikau, Kyoko Hotta, M. Cristine Charlesworth, Thomas A. White, Hirohito Kita, Yoshinari Inoue
Publikováno v:
The Journal of Immunology. 183:6708-6716
Eosinophils are multifunctional leukocytes implicated in the pathogenesis of asthma and in immunity to certain organisms. Associations between exposure to an environmental fungus, such as Alternaria, and asthma have been recognized clinically. Protea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4e3bd7db4cbe673b1a179d3a988355c
https://doi.org/10.4049/jimmunol.0901220
https://doi.org/10.4049/jimmunol.0901220
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 9:581-589
Unlike the earlier agents in this class, certain of the newer histamine H(2)-receptor antagonists (so-called second-generation HB(2B)-receptor antagonists) have recently been reported to promote gastric mucosal defenses. We review herein the structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c3d86d4e8387426ce9b64f1c1b0829
https://doi.org/10.2174/138955709788167646
https://doi.org/10.2174/138955709788167646
Autor:
Kyoko Hotta, Hiroyoshi Ota, Kazuhiko Ishihara, Fukuto Maruta, Tomoaki Ikezawa, Atsushi Sugiyama, Takafumi Ichikawa
Publikováno v:
Journal of Gastroenterology and Hepatology. 22:1800-1805
Background and Aim: Lafutidine is a novel histamine H2-receptor antagonist used primarily as an antisecretory agent in Japan. Previous human studies have not assessed its gastroprotective effects. The purpose of the present study was to determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568a996d45e74759e7f08aac2aed0d26
https://doi.org/10.1111/j.1440-1746.2006.04721.x
https://doi.org/10.1111/j.1440-1746.2006.04721.x
Autor:
Takafumi Ichikawa, Daigo Tsubokawa, Noriko Sato, Yukinobu Goso, Tatsuo Suganuma, Makoto Kurihara, Kazuhiko Ishihara, Kyoko Hotta, Akira Sawaguchi
Publikováno v:
FEBS Journal. 274:1833-1848
Mucin, a major component of mucus, is a highly O-glycosylated, high-molecular-mass glycoprotein extensively involved in the physiology of gastrointestinal mucosa. To detect and characterize mucins derived from site-specific mucous cells, we developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::414507722755424966270f0c9837cd10
https://doi.org/10.1111/j.1742-4658.2007.05731.x
https://doi.org/10.1111/j.1742-4658.2007.05731.x
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 130:375-383
alpha-L-Fucosidases were found in the culture fluid of Streptomyces sp. OH11242 grown with porcine gastric mucin (PGM) as the sole carbon source. The alpha-L-fucosidases were purified by ammonium sulfate precipitation followed by chromatography on Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18beb1a5173cd36e46dd9c519de9faa
https://doi.org/10.1016/s1096-4959(01)00442-0
https://doi.org/10.1016/s1096-4959(01)00442-0
Autor:
Kazuhiko Ishihara, Isao Okayasu, Kyoko Hotta, Y Z Wang, Hiroyuki Mitomi, H Tanigawa, M Kurihara
Publikováno v:
Histopathology. 37:250-259
Aims To investigate the histogenetic relationship between gastric epithelial neoplasms we studied differences in expression of mucin carbohydrate antigens and mucin core protein, in normal and metaplastic gastric mucosa, and in gastric adenomas and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75146ebcbb5b197d80763b3e8ff2eb14
https://doi.org/10.1046/j.1365-2559.2000.00991.x
https://doi.org/10.1046/j.1365-2559.2000.00991.x
Publikováno v:
Life Sciences. 67:1095-1101
Although epidermal growth factor (EGF) accelerates gastric mucin biosynthesis, information on whether its activation is limited to the specific mucus-producing cells is lacking. In this paper, we investigated the effects of EGF on mucin biosynthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0430a380ef8da89bbbb05d88f4f12456
https://doi.org/10.1016/s0024-3205(00)00697-4
https://doi.org/10.1016/s0024-3205(00)00697-4
Autor:
Hiromi Hiruma, Tadashi Kawakami, Kazuhiko Ishihara, Tatsumi Kusakabe, Takafumi Ichikawa, Kyoko Hotta
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 279:G82-G89
We examined the effects of the calcitonin gene-related peptide (CGRP), including the possible participation of nitric oxide (NO), on mucin biosynthesis in the surface epithelium and remaining deep mucosa as well as the entire mucosa and compared the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452801138251c09ce7e304ea4fbd266c
https://doi.org/10.1152/ajpgi.2000.279.1.g82
https://doi.org/10.1152/ajpgi.2000.279.1.g82
Publikováno v:
European Journal of Pharmacology. 392:87-91
We investigated the effects of hepatocyte growth factor (HGF) on mucin biosynthesis and the expression of its receptor in distinct sites and layers of rat gastric mucosa. HGF stimulated the mucin biosynthesis in the surface and gland mucus cells of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc495eef1b8e9bbed3ddfd7375bdb58
https://doi.org/10.1016/s0014-2999(00)00111-4
https://doi.org/10.1016/s0014-2999(00)00111-4