Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Kyoko, Shinya"'
Autor:
Chairul A. Nidom, Ryo Takano, Shinya Yamada, Yuko Sakai-Tagawa, Syafril Daulay, Didi Aswadi, Takashi Suzuki, Yasuo Suzuki, Kyoko Shinya, Kiyoko Iwatsuki-Horimoto, Yukiko Muramoto, Yoshihiro Kawaoka
Publikováno v:
Emerging Infectious Diseases, Vol 16, Iss 10, Pp 1515-1523 (2010)
Pigs have long been considered potential intermediate hosts in which avian influenza viruses can adapt to humans. To determine whether this potential exists for pigs in Indonesia, we conducted surveillance during 2005–2009. We found that 52 pigs in
Externí odkaz:
https://doaj.org/article/e77d7430fabe47b983b5b70890ccfd37
Autor:
Masato Hatta, Yasuko Hatta, Jin Hyun Kim, Shinji Watanabe, Kyoko Shinya, Tung Nguyen, Phuong Song Lien, Quynh Mai Le, Yoshihiro Kawaoka
Publikováno v:
PLoS Pathogens, Vol 3, Iss 10, Pp 1374-1379 (2007)
Highly pathogenic avian H5N1 influenza A viruses have spread throughout Asia, Europe, and Africa, raising serious worldwide concern about their pandemic potential. Although more than 250 people have been infected with these viruses, with a consequent
Externí odkaz:
https://doaj.org/article/815bc27a63d047dd9bf1f3227453c691
Autor:
Yasuko Hatta, Karen Hershberger, Kyoko Shinya, Sean C Proll, Richard R Dubielzig, Masato Hatta, Michael G Katze, Yoshihiro Kawaoka, M Suresh
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001139 (2010)
Since the first recorded infection of humans with H5N1 viruses of avian origin in 1997, sporadic human infections continue to occur with a staggering mortality rate of >60%. Although sustained human-to-human transmission has not occurred yet, there i
Externí odkaz:
https://doaj.org/article/6a1e8ec4b5164f69b12c6340dee70d21
Autor:
Maki Kiso, Kyoko Shinya, Masayuki Shimojima, Ryo Takano, Kei Takahashi, Hiroaki Katsura, Satoshi Kakugawa, Mai Thi Quynh Le, Makoto Yamashita, Yousuke Furuta, Makoto Ozawa, Yoshihiro Kawaoka
Publikováno v:
PLoS Pathogens, Vol 6, Iss 8, p e1001079 (2010)
Influenza viruses resistant to antiviral drugs emerge frequently. Not surprisingly, the widespread treatment in many countries of patients infected with 2009 pandemic influenza A (H1N1) viruses with the neuraminidase (NA) inhibitors oseltamivir and z
Externí odkaz:
https://doaj.org/article/a841cc85efda4453aa7b11f42a01f56d
Autor:
Shinya Yamada, Masato Hatta, Bart L Staker, Shinji Watanabe, Masaki Imai, Kyoko Shinya, Yuko Sakai-Tagawa, Mutsumi Ito, Makoto Ozawa, Tokiko Watanabe, Saori Sakabe, Chengjun Li, Jin Hyun Kim, Peter J Myler, Isabelle Phan, Amy Raymond, Eric Smith, Robin Stacy, Chairul A Nidom, Simon M Lank, Roger W Wiseman, Benjamin N Bimber, David H O'Connor, Gabriele Neumann, Lance J Stewart, Yoshihiro Kawaoka
Publikováno v:
PLoS Pathogens, Vol 6, Iss 8, p e1001034 (2010)
Two amino acids (lysine at position 627 or asparagine at position 701) in the polymerase subunit PB2 protein are considered critical for the adaptation of avian influenza A viruses to mammals. However, the recently emerged pandemic H1N1 viruses lack
Externí odkaz:
https://doaj.org/article/8fe7cb48869b484fa343e34b271f36e4
Autor:
Hirotaka Imai, Kyoko Shinya, Ryo Takano, Maki Kiso, Yukiko Muramoto, Saori Sakabe, Shin Murakami, Mutsumi Ito, Shinya Yamada, Mai Thi Quynh Le, Chairul A Nidom, Yuko Sakai-Tagawa, Kei Takahashi, Yasuyuki Omori, Takeshi Noda, Masayuki Shimojima, Satoshi Kakugawa, Hideo Goto, Kiyoko Iwatsuki-Horimoto, Taisuke Horimoto, Yoshihiro Kawaoka
Publikováno v:
PLoS Pathogens, Vol 6, Iss 9, p e1001106 (2010)
Highly pathogenic H5N1 influenza A viruses have spread across Asia, Europe, and Africa. More than 500 cases of H5N1 virus infection in humans, with a high lethality rate, have been reported. To understand the molecular basis for the high virulence of
Externí odkaz:
https://doaj.org/article/c2a93147bc3a49a2a7dd819201599097
Autor:
Yuwei Gao, Ying Zhang, Kyoko Shinya, Guohua Deng, Yongping Jiang, Zejun Li, Yuntao Guan, Guobin Tian, Yanbing Li, Jianzhong Shi, Liling Liu, Xianying Zeng, Zhigao Bu, Xianzhu Xia, Yoshihiro Kawaoka, Hualan Chen
Publikováno v:
PLoS Pathogens, Vol 5, Iss 12, p e1000709 (2009)
Since 2003, H5N1 influenza viruses have caused over 400 known cases of human infection with a mortality rate greater than 60%. Most of these cases resulted from direct contact with virus-contaminated poultry or poultry products. Although only limited
Externí odkaz:
https://doaj.org/article/7d33d7b2fe9846d5bcbc0ff810642c14
Autor:
Cristian Cillóniz, Kyoko Shinya, Xinxia Peng, Marcus J Korth, Sean C Proll, Lauri D Aicher, Victoria S Carter, Jean H Chang, Darwyn Kobasa, Friedericke Feldmann, James E Strong, Heinz Feldmann, Yoshihiro Kawaoka, Michael G Katze
Publikováno v:
PLoS Pathogens, Vol 5, Iss 10, p e1000604 (2009)
The enormous toll on human life during the 1918-1919 Spanish influenza pandemic is a constant reminder of the potential lethality of influenza viruses. With the declaration by the World Health Organization of a new H1N1 influenza virus pandemic, and
Externí odkaz:
https://doaj.org/article/69146b6be9d7436f83aa9050f9bb54c6
Autor:
Shufang Fan, Yuwei Gao, Kyoko Shinya, Chris Kafai Li, Yanbing Li, Jianzhong Shi, Yongping Jiang, Yongbing Suo, Tiegang Tong, Gongxun Zhong, Jiasheng Song, Ying Zhang, Guobin Tian, Yuntao Guan, Xiao-Ning Xu, Zhigao Bu, Yoshihiro Kawaoka, Hualan Chen
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000409 (2009)
The continued spread of highly pathogenic H5N1 influenza viruses among poultry and wild birds, together with the emergence of drug-resistant variants and the possibility of human-to-human transmission, has spurred attempts to develop an effective vac
Externí odkaz:
https://doaj.org/article/004572bb00e74b8d8577664f1e42be2e
Autor:
null Yumi Ueda, null Motoko Tanaka, null Yukihiro Kyan, null Mitsutaka Yoshida, null Kenji Sasahara, null Kyoko Shinya
Publikováno v:
Journal of Basic & Applied Sciences. 10:1-6
In 2001, the 11th influenza A viral protein PB1-F2 was detected and found to be encoded by an alternative open reading frame in the PB1 polymerase gene. PB1-F2 has several unique functions, including roles in promoting apoptosis, increasing inflammat