Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Kyoji Hagiwara"'
Autor:
Seii Ohka, Soon Hao Tan, Eri Ishiyama, Katsutoshi Ogasawara, Tomohito Hanasaka, Kinji Ishida, Kyoji Hagiwara, Chia-Chyi Liu, Pele Choi-Sing Chong, Ken-ichi Hanaki, Giampietro Schiavo
Publikováno v:
Biology Open, Vol 11, Iss 9 (2022)
Enterovirus 71 (EV71) is one of the causative agents of hand-foot-and-mouth disease, which in some circumstances could lead to severe neurological diseases. Despite of its importance for human health, little is known about the early stages of EV71 in
Externí odkaz:
https://doaj.org/article/90ce2a44bb254da09105e56db4ca9c9f
Autor:
Ryosuke Matsuura, Ken Maeda, Kyoji Hagiwara, Yosuke Mori, Toru Kitamura, Yasunobu Matsumoto, Yoko Aida
Publikováno v:
Pathogens, Vol 11, Iss 8, p 922 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019, which has been a global pandemic. Since SARS-CoV-2 is transmitted through contaminated surfaces and aerosols, environmental disinfection
Externí odkaz:
https://doaj.org/article/625bfd7073f744718f1ec3ac7049cf4b
Autor:
Hironobu Murakami, Takehiro Suzuki, Kiyoto Tsuchiya, Hiroyuki Gatanaga, Manabu Taura, Eriko Kudo, Seiji Okada, Masami Takei, Kazumichi Kuroda, Tatsuo Yamamoto, Kyoji Hagiwara, Naoshi Dohmae, Yoko Aida
Publikováno v:
Viruses, Vol 12, Iss 3, p 355 (2020)
Current therapies for human immunodeficiency virus type 1 (HIV-1) do not completely eliminate viral reservoirs in cells, such as macrophages. The HIV-1 accessory protein viral protein R (Vpr) promotes virus production in macrophages, and the maintena
Externí odkaz:
https://doaj.org/article/7e4e09822885477a821d527d00cab213
Autor:
Kyoji Hagiwara, Hideki Ishii, Tomoyuki Murakami, Shin-nosuke Takeshima, Nopporn Chutiwitoonchai, Eiichi N Kodama, Kumi Kawaji, Yasumitsu Kondoh, Kaori Honda, Hiroyuki Osada, Yasuko Tsunetsugu-Yokota, Masaaki Suzuki, Yoko Aida
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145573 (2015)
The emergence of multidrug-resistant viruses compromises the efficacy of anti-human immunodeficiency virus type 1 (HIV-1) therapy and limits treatment options. Therefore, new targets that can be used to develop novel antiviral agents need to be ident
Externí odkaz:
https://doaj.org/article/ba129c7472764fcab634ab5e88aab3dc
Autor:
Yutaka Sasaki, Kyoji Hagiwara, Michinori Kakisaka, Kazunori Yamada, Tomoyuki Murakami, Yoko Aida
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55765 (2013)
The nucleoprotein (NP) of influenza A virus is transported into the nucleus via the classical importin α/β pathway, and proceeds via nuclear localization signals (NLSs) recognized by importin α molecules. Although NP binds to importin α isoforms
Externí odkaz:
https://doaj.org/article/9a2ba5d1c0f54a4aaa383e0f6ad6e714
Autor:
Yutaka Sasaki, Kyoji Hagiwara, Michinori Kakisaka, Kazunori Yamada, Tomoyuki Murakami, Yoko Aida
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/5f62775b67d64b17bc44a8de8ac52985
Autor:
Ryosuke, Matsuura, Ken, Maeda, Kyoji, Hagiwara, Yosuke, Mori, Toru, Kitamura, Yasunobu, Matsumoto, Yoko, Aida
Publikováno v:
Pathogens (Basel, Switzerland). 11(8)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019, which has been a global pandemic. Since SARS-CoV-2 is transmitted through contaminated surfaces and aerosols, environmental disinfection
Publikováno v:
ACS Chemical Biology. 16:316-323
Inhibiting the programmed death-1 (PD-1)/programmed death ligand 1 (PD-L1) axis by monoclonal antibodies (mAbs) is a successful cancer immunotherapy. However, mAb-based drugs have various disadvantages including high production costs and large molecu
Autor:
Boyang, Ning, Xueli, Ren, Kyoji, Hagiwara, Shinji, Takeoka, Yoshihiro, Ito, Hideyuki, Miyatake
Publikováno v:
ACS chemical biology. 16(2)
Inhibiting the programmed death-1 (PD-1)/programmed death ligand 1 (PD-L1) axis by monoclonal antibodies (mAbs) is a successful cancer immunotherapy. However, mAb-based drugs have various disadvantages including high production costs and large molecu
Autor:
Kyoji Hagiwara, Yoshihiro Ito, Yue Zhou, Takashi Isoshima, Baiju G. Nair, Masashi Ueki, Hiroshi Abe
Publikováno v:
Journal of materials chemistry. B. 5(22)
Nanostructured RNA carrying three different siRNAs was assembled to silence three target genes (Axin, APC, and GSK-3β) in the Wnt/β-catenin signaling pathway. The trimer RNA nanostructure included equimolar concentrations of three oligonucleotide s