Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Kyoichi, Ono"'
Publikováno v:
Journal of Primary Care & Community Health, Vol 14 (2023)
Introduction: While there may be differences in the choice of suicide methods between attempters with and those without a history of psychiatric disorders, it is not clear whether these differences predict the actual degree of physical injury. The pr
Externí odkaz:
https://doaj.org/article/33442aa935de42988f7c1c11fd6241f7
Autor:
Kyoko Nomura, Teiichiro Yamazaki, Eri Maeda, Junko Hirayama, Kyoichi Ono, Masahito Fushimi, Kazuo Mishima, Fumio Yamamoto
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
While changes in response to the different stages of the pandemic remain unknown, this study investigated the longitudinal impact of the COVID-19 pandemic on depressive symptoms in Japanese university students and identified factors associated with n
Externí odkaz:
https://doaj.org/article/0c27194cc5d94a6ea8eb9b9e8b47fbe1
Autor:
Manabu Murakami, Feng Xu, Takayoshi Ohba, Takeshi Kobayashi, Yoshiro Inoue, Agnieszka M. Murakami, Ichiro Miyoshi, Kyoichi Ono, Noritsugu Tohse
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 3, Pp 253-261 (2021)
Facilitation of cardiac function in response to signals from the sympathetic nervous system is initiated by the phosphorylation of L-type voltage-dependent Ca2+ channels (VDCCs) by protein kinase A (PKA), which in turn is activated by β-adrenoceptor
Externí odkaz:
https://doaj.org/article/92d608b1bac14dea80ab12b7cd05b0cf
Autor:
Kyoko Nomura, Sachiko Minamizono, Eri Maeda, Roseline Kim, Toyoto Iwata, Junko Hirayama, Kyoichi Ono, Masahito Fushimi, Takeshi Goto, Kazuo Mishima, Fumio Yamamoto
Publikováno v:
Environmental Health and Preventive Medicine, Vol 26, Iss 1, Pp 1-9 (2021)
Abstract Background We aimed to estimate the prevalence of depressive symptoms as well as suicide-related ideation among Japanese university students during the stay-home order necessitated by the coronavirus disease 2019 pandemic in Japan, and offer
Externí odkaz:
https://doaj.org/article/da906740f0fd463791458fa72164c274
Autor:
Yosuke Okamoto, Kyoichi Ono
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1393 (2022)
The heart is a necessary organ for sustaining life in mammals, and it is the first organ to function during early development [...]
Externí odkaz:
https://doaj.org/article/521e81252eb642708da6c44656f04f72
Autor:
Kiichi Takahashi, Takayoshi Ohba, Yosuke Okamoto, Atsuko Noguchi, Hiroko Okuda, Hatasu Kobayashi, Kouji H. Harada, Akio Koizumi, Kyoichi Ono, Tsutomu Takahashi
Publikováno v:
Heliyon, Vol 7, Iss 6, Pp e07396- (2021)
Gain-of-function mutations in voltage-gated sodium channels (NaV1.7, NaV1.8, and NaV1.9) are known causes of inherited pain disorders. Identification and functional assessment of new NaV1.7 mutations could help elucidate the phenotypic spectrum of Na
Externí odkaz:
https://doaj.org/article/48c5388dbd0a40fc9ca837a09f833e6b
Autor:
Daigo Okada, Yosuke Okamoto, Toshiro Io, Miho Oka, Daiki Kobayashi, Suzuka Ito, Ryo Yamada, Kuniaki Ishii, Kyoichi Ono
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 859 (2022)
The heart is a significant organ in mammalian life, and the heartbeat mechanism has been an essential focus of science. However, few studies have focused on species differences. Accordingly, challenges remain in studying genes that have universal fun
Externí odkaz:
https://doaj.org/article/4f8d9f3ba4b64a11a0a6fc9ad1c4400c
Autor:
Yosuke Okamoto, Naing Ye Aung, Masahiro Tanaka, Yuji Takeda, Daichi Takagi, Wataru Igarashi, Kuniaki Ishii, Mitsunori Yamakawa, Kyoichi Ono
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 724 (2022)
Ectopic excitability in pulmonary veins (PVs) is the major cause of atrial fibrillation. We previously reported that the inositol trisphosphate receptor in rat PV cardiomyocytes cooperates with the Na+-Ca2+ exchanger to provoke ectopic automaticity i
Externí odkaz:
https://doaj.org/article/e33f9996a3a34565a6e5c4c2b3ba311f
Autor:
Manabu Yonekura, Nami Kondoh, Chong Han, Yuichi Toyama, Takayoshi Ohba, Kyoichi Ono, Shirou Itagaki, Hirofumi Tomita, Manabu Murakami
Publikováno v:
Journal of Pharmacological Sciences, Vol 137, Iss 1, Pp 55-60 (2018)
The heart of the medaka, a small fish native to East Asia, has electrophysiological aspects similar to mammalian hearts. We found that the heart rates of medaka were more similar to humans than mice or rats. Medaka exhibited similar electrocardiogram
Externí odkaz:
https://doaj.org/article/ae0fed1c0e0d4cb59fcc548b26c4b955
Autor:
Okamoto, Wataru Igarashi, Daichi Takagi, Daigo Okada, Daiki Kobayashi, Miho Oka, Toshiro Io, Kuniaki Ishii, Kyoichi Ono, Hiroshi Yamamoto, Yosuke
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10501
Atrial fibrillation (AF) is the most frequent persistent arrhythmia. Many genes have been reported as a genetic background for AF. However, most transcriptome analyses of AF are limited to the atrial samples and have not been evaluated by multiple ca