Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Kyohei NAKAMURA"'
Autor:
Mika Casey, Carol Lee, Sharon M. Hoyte, Rebecca L. Johnston, Wing Yu Kwok, Soi Cheng Law, Maher K Gandhi, Simon J Harrison, Kyohei Nakamura
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
T-cell-engaging bispecific antibody (T-BsAb, also known as BiTE) therapy has emerged as a powerful therapeutic modality against multiple myeloma. Given that T-BsAb therapy redirects endogenous T cells to eliminate tumor cells, reinvigorating dysfunct
Externí odkaz:
https://doaj.org/article/e2b3c87782cc4f26af9c0283b3578f4b
Autor:
Rebecca J. Austin, Jasmin Straube, Rohit Halder, Yashaswini Janardhanan, Claudia Bruedigam, Matthew Witkowski, Leanne Cooper, Amy Porter, Matthias Braun, Fernando Souza-Fonseca-Guimaraes, Simone A. Minnie, Emily Cooper, Sebastien Jacquelin, Axia Song, Tobias Bald, Kyohei Nakamura, Geoffrey R. Hill, Iannis Aifantis, Steven W. Lane, Megan J. Bywater
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Acute myeloid leukemia (AML) is a genetically heterogeneous, aggressive hematological malignancy induced by distinct oncogenic driver mutations. The effect of specific AML oncogenes on immune activation or suppression is unclear. Here, we ex
Externí odkaz:
https://doaj.org/article/1fe1b18939ee4e878a49fa928f9e503d
Autor:
Mika Casey, Carol Lee, Wing Yu Kwok, Soi Cheng Law, Dillon Corvino, Maher K Gandhi, Simon J Harrison, Kyohei Nakamura
Publikováno v:
Haematologica, Vol 109, Iss 3 (2023)
T-cell-engaging bispecific antibodies (T-BsAb) have produced impressive clinical responses in patients with relapsed/refractory B-cell malignancies, although treatment failure remains a major clinical challenge. Growing evidence suggests that a compl
Externí odkaz:
https://doaj.org/article/b870098d16af4da8a6a9bc4158d2a216
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-19 (2020)
Abstract Immune checkpoint blockade (ICB) therapies such as anti-programmed death 1 (PD-1) and anti-CTLA-4 (cytotoxic T lymphocyte-associated protein 4) have dramatically transformed treatment in solid tumor oncology. While immunotherapeutic approach
Externí odkaz:
https://doaj.org/article/3516c5caeda84522b90911171fbcb438
Autor:
Xian-Yang Li, Indrajit Das, Ailin Lepletier, Venkateswar Addala, Tobias Bald, Kimberley Stannard, Deborah Barkauskas, Jing Liu, Amelia Roman Aguilera, Kazuyoshi Takeda, Matthias Braun, Kyohei Nakamura, Sebastien Jacquelin, Steven W. Lane, Michele W.L. Teng, William C. Dougall, Mark J. Smyth
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/c9ff9423cab74ff68d9f525d5673d4ce
Autor:
Jing Liu, Elizabeth McDonald, Mark J Smyth, Celia Jacoberger-Foissac, Stephen J Blake, Hannah Triscott, Kyohei Nakamura, Michele WL Teng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Concomitant tumor necrosis factor (TNF) neutralization in combination with immune checkpoint inhibitors (ICIs) reduces clinical immune-related adverse events (irAEs) and appears to improve antitumor efficacy in preclinical tumor models. Ag
Externí odkaz:
https://doaj.org/article/98011a2979a34e438c9c70b413533f3a
Autor:
Yoshinao KISHIMOTO, Yukiyoshi KOBAYASHI, Toshihisa OHTSUKA, Shota ONO, Hiroshi YAMAZAKI, Yuki TSUKAGOSHI, Kyohei NAKAMURA
Publikováno v:
Mechanical Engineering Journal, Vol 7, Iss 4, Pp 19-00545-19-00545 (2020)
Lithium-ion batteries (LIBs) are expected to be main power sources of automobiles. Nevertheless, LIBs easily lead to serious incidents because LIBs have high energy density. For application to automobiles, the reliability of LIBs should be guaranteed
Externí odkaz:
https://doaj.org/article/054a056f3a1e48259b74d066426f5d73
Autor:
Jun Hui Sze, Prahlad V. Raninga, Kyohei Nakamura, Mika Casey, Kum Kum Khanna, Susan J. Berners-Price, Giovanna Di Trapani, Kathryn F. Tonissen
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Multiple myeloma (MM), the second most common haematological malignancy, is a clonal plasma B-cell neoplasm that forms within the bone marrow. Despite recent advancements in treatment, MM remains an incurable disease. Auranofin, a linear gold(I) phos
Externí odkaz:
https://doaj.org/article/8f24779605f34d5986f2b92b03fc7460
Autor:
Toshimasa Kusaka, Masafumi Nakayama, Kyohei Nakamura, Mai Ishimiya, Emi Furusawa, Kouetsu Ogasawara
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92634 (2014)
Amorphous silica particles, such as nanoparticles (
Externí odkaz:
https://doaj.org/article/46c4ea519eec4f94aa68caac90ff0e76
Autor:
Mitsuko Kawano, Masafumi Nakayama, Yusuke Aoshima, Kyohei Nakamura, Mizuho Ono, Tadashi Nishiya, Syou Nakamura, Yuri Takeda, Akira Dobashi, Akiko Takahashi, Misato Endo, Akiyo Ito, Kyosuke Ueda, Naoki Sato, Shigehito Higuchi, Takeru Kondo, Suguru Hashimoto, Masamichi Watanabe, Makoto Watanabe, Tetsu Takahashi, Keiichi Sasaki, Masanori Nakamura, Takehiko Sasazuki, Takayuki Narushima, Ryuji Suzuki, Kouetsu Ogasawara
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86810 (2014)
Nickel, cobalt, and chromium are well known to be causal agents of allergic contact dermatitis. Palladium (Pd) can also cause allergic disease and exposure results from wide use of this metal in dental restorations and jewelry. Metal allergy is categ
Externí odkaz:
https://doaj.org/article/dddeb260a2584eb58f39885196981ae9