Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Kyohei Kin"'
Autor:
Yosuke Okazaki, Tatsuya Sasaki, Kakeru Hosomoto, Shun Tanimoto, Koji Kawai, Takayuki Nagase, Chiaki Sugahara, Satoru Yabuno, Kyohei Kin, Susumu Sasada, Takao Yasuhara, Shota Tanaka, Isao Date
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Epidural spinal cord stimulation (SCS) is indicated for the treatment of intractable pain and is widely used in clinical practice. In previous basic research, the therapeutic effects of SCS have been demonstrated for epileptic seizure. Howev
Externí odkaz:
https://doaj.org/article/7a482031f28a469aaea91866806bc79c
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Adolescent stress can be a risk factor for abnormal social behavior in the postpartum period, which critically affects an individual social functioning. Nonetheless, the underlying mechanisms remain unclear. Using a mouse model with optogene
Externí odkaz:
https://doaj.org/article/40506b2f42d946d990547368eaf89470
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2773 (2023)
The interruption of cerebral blood flow leads to ischemic cell death and results in ischemic stroke. Although ischemic stroke is one of the most important causes of long-term disability and mortality, limited treatments are available for functional r
Externí odkaz:
https://doaj.org/article/ee690905b0ff4bef89bc648b49928cde
Publikováno v:
Neuroscience Insights, Vol 15 (2020)
Mesenchymal stem cells (MSCs) are widely considered good candidates for cell transplantation therapy. Various central nervous system disorders have been suggested as suitable targets for MSC transplantation therapy. In this context, a great deal of b
Externí odkaz:
https://doaj.org/article/9333b94759224cd19433bb2acea0ce05
Autor:
Ken Kuwahara, Tatsuya Sasaki, Takao Yasuhara, Masahiro Kameda, Yosuke Okazaki, Kakeru Hosomoto, Ittetsu Kin, Mihoko Okazaki, Satoru Yabuno, Satoshi Kawauchi, Yousuke Tomita, Michiari Umakoshi, Kyohei Kin, Jun Morimoto, Jea-Young Lee, Naoki Tajiri, Cesar V. Borlongan, Isao Date
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
BackgroundSpinal cord stimulation (SCS) exerts neuroprotective effects in animal models of Parkinson’s disease (PD). Conventional stimulation techniques entail limited stimulation time and restricted movement of animals, warranting the need for opt
Externí odkaz:
https://doaj.org/article/b24bd04c62364b859918b228d01438bb
Autor:
Jun Morimoto, Takao Yasuhara, Masahiro Kameda, Michiari Umakoshi, Ittetsu Kin, Ken Kuwahara, Kyohei Kin, Mihoko Okazaki, Hayato Takeuchi, Tatsuya Sasaki, Atsuhiko Toyoshima, Naoki Tajiri, Takashi Agari, Cesario V. Borlongan, Isao Date
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 1, Pp 57-68 (2018)
Background/Aims: Bone marrow stromal cells (BMSCs) transplantation is an important strategy for the treatment of ischemic stroke. Currently, there are no effective methods to guide BMSCs toward the targeted site. In this study, we investigated the ef
Externí odkaz:
https://doaj.org/article/a982ca15a12149d1855d1e2bdfc0930c
Publikováno v:
Brain Circulation, Vol 4, Iss 3, Pp 128-132 (2018)
As prevalence of depression continues to rise around the world, there remains a stagnation of available treatments as the affected population grows. The subset of treatment-resistant depression also is on the rise highlighting the need for innovative
Externí odkaz:
https://doaj.org/article/65d6508060d2444b90d59206e2187411
Autor:
Ittetsu Kin, Tatsuya Sasaki, Takao Yasuhara, Masahiro Kameda, Takashi Agari, Mihoko Okazaki, Kakeru Hosomoto, Yosuke Okazaki, Satoru Yabuno, Satoshi Kawauchi, Ken Kuwahara, Jun Morimoto, Kyohei Kin, Michiari Umakoshi, Yousuke Tomita, Naoki Tajiri, Cesario V. Borlongan, Isao Date
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 789 (2021)
Background: The major surgical treatment for Parkinson’s disease (PD) is deep brain stimulation (DBS), but a less invasive treatment is desired. Vagus nerve stimulation (VNS) is a relatively safe treatment without cerebral invasiveness. In this stu
Externí odkaz:
https://doaj.org/article/65a38fddab754228bcf3f86bb676269b
Autor:
Naoya Kidani, Tomohito Hishikawa, Masafumi Hiramatsu, Shingo Nishihiro, Kyohei Kin, Yu Takahashi, Satoshi Murai, Kenji Sugiu, Takao Yasuhara, Ikuko Miyazaki, Masato Asanuma, Isao Date
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4137 (2020)
Crossed cerebellar diaschisis (CCD) is a state of hypoperfusion and hypometabolism in the contralesional cerebellar hemisphere caused by a supratentorial lesion, but its pathophysiology is not fully understood. We evaluated chronological changes in c
Externí odkaz:
https://doaj.org/article/41e1fb535312411ab272bc708d68f8be
Autor:
Hayato Takeuchi, Masahiro Kameda, Takao Yasuhara, Tatsuya Sasaki, Atsuhiko Toyoshima, Jun Morimoto, Kyohei Kin, Mihoko Okazaki, Michiari Umakoshi, Ittetsu Kin, Ken Kuwahara, Yosuke Tomita, Isao Date
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Several reports have shown that long-term potentiation (LTP) per se effectively enhances neurogenesis in the hippocampus of intact animals. If LTP can enhance neurogenesis in chronic hypoperfusion, this approach could potentially become a new therape
Externí odkaz:
https://doaj.org/article/20c9c57f64c047d0a5b117a16901185b