Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kyohei, Kin"'
Autor:
Yosuke Okazaki, Tatsuya Sasaki, Kakeru Hosomoto, Shun Tanimoto, Koji Kawai, Takayuki Nagase, Chiaki Sugahara, Satoru Yabuno, Kyohei Kin, Susumu Sasada, Takao Yasuhara, Shota Tanaka, Isao Date
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Epidural spinal cord stimulation (SCS) is indicated for the treatment of intractable pain and is widely used in clinical practice. In previous basic research, the therapeutic effects of SCS have been demonstrated for epileptic seizure. Howev
Externí odkaz:
https://doaj.org/article/7a482031f28a469aaea91866806bc79c
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Adolescent stress can be a risk factor for abnormal social behavior in the postpartum period, which critically affects an individual social functioning. Nonetheless, the underlying mechanisms remain unclear. Using a mouse model with optogene
Externí odkaz:
https://doaj.org/article/40506b2f42d946d990547368eaf89470
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2773 (2023)
The interruption of cerebral blood flow leads to ischemic cell death and results in ischemic stroke. Although ischemic stroke is one of the most important causes of long-term disability and mortality, limited treatments are available for functional r
Externí odkaz:
https://doaj.org/article/ee690905b0ff4bef89bc648b49928cde
Publikováno v:
Neuroscience Insights, Vol 15 (2020)
Mesenchymal stem cells (MSCs) are widely considered good candidates for cell transplantation therapy. Various central nervous system disorders have been suggested as suitable targets for MSC transplantation therapy. In this context, a great deal of b
Externí odkaz:
https://doaj.org/article/9333b94759224cd19433bb2acea0ce05
Autor:
Ken Kuwahara, Tatsuya Sasaki, Takao Yasuhara, Masahiro Kameda, Yosuke Okazaki, Kakeru Hosomoto, Ittetsu Kin, Mihoko Okazaki, Satoru Yabuno, Satoshi Kawauchi, Yousuke Tomita, Michiari Umakoshi, Kyohei Kin, Jun Morimoto, Jea-Young Lee, Naoki Tajiri, Cesar V. Borlongan, Isao Date
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
BackgroundSpinal cord stimulation (SCS) exerts neuroprotective effects in animal models of Parkinson’s disease (PD). Conventional stimulation techniques entail limited stimulation time and restricted movement of animals, warranting the need for opt
Externí odkaz:
https://doaj.org/article/b24bd04c62364b859918b228d01438bb
Autor:
Jun Morimoto, Takao Yasuhara, Masahiro Kameda, Michiari Umakoshi, Ittetsu Kin, Ken Kuwahara, Kyohei Kin, Mihoko Okazaki, Hayato Takeuchi, Tatsuya Sasaki, Atsuhiko Toyoshima, Naoki Tajiri, Takashi Agari, Cesario V. Borlongan, Isao Date
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 1, Pp 57-68 (2018)
Background/Aims: Bone marrow stromal cells (BMSCs) transplantation is an important strategy for the treatment of ischemic stroke. Currently, there are no effective methods to guide BMSCs toward the targeted site. In this study, we investigated the ef
Externí odkaz:
https://doaj.org/article/a982ca15a12149d1855d1e2bdfc0930c
Publikováno v:
Brain Circulation, Vol 4, Iss 3, Pp 128-132 (2018)
As prevalence of depression continues to rise around the world, there remains a stagnation of available treatments as the affected population grows. The subset of treatment-resistant depression also is on the rise highlighting the need for innovative
Externí odkaz:
https://doaj.org/article/65d6508060d2444b90d59206e2187411
Autor:
Ittetsu Kin, Tatsuya Sasaki, Takao Yasuhara, Masahiro Kameda, Takashi Agari, Mihoko Okazaki, Kakeru Hosomoto, Yosuke Okazaki, Satoru Yabuno, Satoshi Kawauchi, Ken Kuwahara, Jun Morimoto, Kyohei Kin, Michiari Umakoshi, Yousuke Tomita, Naoki Tajiri, Cesario V. Borlongan, Isao Date
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 789 (2021)
Background: The major surgical treatment for Parkinson’s disease (PD) is deep brain stimulation (DBS), but a less invasive treatment is desired. Vagus nerve stimulation (VNS) is a relatively safe treatment without cerebral invasiveness. In this stu
Externí odkaz:
https://doaj.org/article/65a38fddab754228bcf3f86bb676269b
Autor:
Satoshi Kawauchi, Takao Yasuhara, Kyohei Kin, Satoru Yabuno, Chiaki Sugahara, Takayuki Nagase, Kakeru Hosomoto, Yosuke Okazaki, Yousuke Tomita, Michiari Umakoshi, Tatsuya Sasaki, Masahiro Kameda, Cesario V. Borlongan, Isao Date
Publikováno v:
CNS Neuroscience & Therapeutics. 28:1974-1985
Aims SB623 cells are human bone marrow stromal cells transfected with Notch1 intracellular domain. In this study, we examined potential regenerative mechanisms underlying stereotaxic transplantation of SB623 cells in rats with experimental acute isch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30eac11b15e5df5a1e5da7bf509cc5d8
https://doi.org/10.1111/cns.13947
https://doi.org/10.1111/cns.13947
Adolescent stress can be a risk factor for abnormal social behavior in the postpartum period, which critically affects the safety of mothers and children. Nonetheless, the underlying mechanisms remain unclear. Using a newly established mouse model wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a409e4a05da48a9fdaf101fd802517aa
https://doi.org/10.1101/2023.01.03.522598
https://doi.org/10.1101/2023.01.03.522598
