TLR4-mediated expression of Mac-1 in monocytes plays a pivotal role in monocyte adhesion to vascular endothelium.

Autor: Seung Jin Lee, Eun Kyoung Choi, Kyo Won Seo, Jin Ung Bae, So Youn Park, Chi Dae Kim

Publikováno v: PLoS ONE, Vol 9, Iss 8, p e104588 (2014)

Toll-like receptor 4 (TLR4) is known to mediate monocyte adhesion to endothelial cells, however, its role on the expression of monocyte adhesion molecules is unclear. In the present study, we investigated the role of TLR4 on the expression of monocyt

Externí odkaz: https://doaj.org/article/58459eb77fc04ff2a6e4ef8d69d9fc1d

Mechanical stretch increases MMP-2 production in vascular smooth muscle cells via activation of PDGFR-β/Akt signaling pathway.

Autor: Kyo Won Seo, Seung Jin Lee, Yun Hak Kim, Jin Ung Bae, So Youn Park, Sun Sik Bae, Chi Dae Kim

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e70437 (2013)

Increased blood pressure, leading to mechanical stress on vascular smooth muscle cells (VSMC), is a known risk factor for vascular remodeling via increased activity of matrix metalloproteinase (MMP) within the vascular wall. This study aimed to ident

Externí odkaz: https://doaj.org/article/df3623cf4e674715856fa5bbcaed8173

Voluntary stand-up physical activity enhances endurance exercise capacity in rats

Autor: Ji Young Yeo, Jin Han, Saranhuu Bolorerdene, Dae Yun Seo, Kyung Soo Ko, Kyo Won Seo, Sung Ryul Lee, Nari Kim, Robin A. McGregor, Tae Hee Ko, Hyo-Bum Kwak, Byoung Doo Rhee

Publikováno v: The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology

Involuntary physical activity induced by the avoidance of electrical shock leads to improved endurance exercise capacity in animals. However, it remains unknown whether voluntary stand-up physical activity (SPA) without forced simulating factors impr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5615acdae7fc2bb8cb75809abe7ede0
http://europepmc.org/articles/PMC4860371

Mechanical stretch enhances the expression and activity of osteopontin and MMP-2 via the Akt1/AP-1 pathways in VSMC

Autor: Sun Sik Bae, Young Whan Kim, Chi Dae Kim, Kyo Won Seo, Byeong Hyeok Ye, Seung Jin Lee

Publikováno v: Journal of Molecular and Cellular Cardiology. 85:13-24

Hemodynamic forces causing mechanical stretch (MS) of vascular smooth muscle cells (VSMC) play an important role in vascular remodeling, but the underlying mechanism involved is not fully understood. Thus, this study investigated whether osteopontin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5b7b55437d9c34d84de6b34e7240cb
https://doi.org/10.1016/j.yjmcc.2015.05.006

Resistin derived from diabetic perivascular adipose tissue up-regulates vascular expression of osteopontin via the AP-1 signalling pathway

Autor: Chi Dae Kim, Seung Jin Lee, Kyu Hee Kim, Kyo Won Seo, So Youn Park, Won Suk Lee, Jin Ung Bae, Yun Hak Kim

Publikováno v: The Journal of Pathology

Perivascular adipose tissue (PVAT) is implicated in the development of vascular diseases; however, the roles of PVAT on OPN expression in diabetic vasculature remain to be determined. This study investigated the role of adipokines derived from diabet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7d8d2a48def2251934196d4ac52a2c
http://europepmc.org/articles/PMC4285806