Long-term phlebotomy successfully alleviated hepatic iron accumulation in a ferroportin disease patient with a mutation in SLC40A1: a case report

Autor: Sohji Nishina, Yasuyuki Tomiyama, Katsuya Ikuta, Yasuaki Tatsumi, Yasumichi Toki, Ayako Kato, Koichi Kato, Naoko Yoshioka, Kyo Sasaki, Yuichi Hara, Keisuke Hino

Publikováno v: BMC Gastroenterology, Vol 21, Iss 1, Pp 1-7 (2021)

Abstract Background Hereditary hemochromatosis is a heterogenous group of inherited iron-overload conditions that is characterized by increased intestinal absorption and deposition in vital organs. Hepcidin is a soluble regulator that acts to attenua

Externí odkaz: https://doaj.org/article/67efaf51fab54a8fb71daf0ee916440d

Dipeptidyl Peptidase 4 Inhibitors Reduce Hepatocellular Carcinoma by Activating Lymphocyte Chemotaxis in MiceSummary

Autor: Sohji Nishina, Akira Yamauchi, Takumi Kawaguchi, Kohei Kaku, Moritaka Goto, Kyo Sasaki, Yuichi Hara, Yasuyuki Tomiyama, Futoshi Kuribayashi, Takuji Torimura, Keisuke Hino

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 115-134 (2019)

Background & Aims: CD26, a multifunctional transmembrane glycoprotein, is expressed in various cancers and functions as dipeptidyl peptidase 4 (DPP4). We investigated whether CD26 expression is associated with hepatocellular carcinoma (HCC) progressi

Externí odkaz: https://doaj.org/article/c531b081775b421fa491de10453b29a8

Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice

Autor: Akira Yamauchi, Masahiro Yamamura, Keisuke Hino, Kyo Sasaki, Yuichi Hara, Fukuda Kotaro, Sohji Nishina, Kensuke Egashira

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 739-762 (2021)

Background & Aims Immune checkpoint inhibitors have shed light on the importance of antitumor immunity as a therapeutic strategy for hepatocellular carcinoma (HCC). The altered glucose metabolism known as the Warburg effect recently has gained attent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010d385be012e5b858cf3e9cba28a067
https://doi.org/10.1016/j.jcmgh.2020.10.010

Long-term phlebotomy successfully alleviated hepatic iron accumulation in a ferroportin disease patient with a mutation in SLC40A1: a case report

Autor: Kyo Sasaki, Yuichi Hara, Yasumichi Toki, Keisuke Hino, Yasuaki Tatsumi, Koichi Kato, Sohji Nishina, Naoko Yoshioka, Yasuyuki Tomiyama, Katsuya Ikuta, Ayako Kato

Publikováno v: BMC Gastroenterology
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-7 (2021)

Background Hereditary hemochromatosis is a heterogenous group of inherited iron-overload conditions that is characterized by increased intestinal absorption and deposition in vital organs. Hepcidin is a soluble regulator that acts to attenuate both i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bb66080a074ceaeb1340875a266a7a
http://europepmc.org/articles/PMC7934381

Usefulness of a CT-guided hookwire marking in laparoscopic partial hepatectomy for hepatocellular carcinoma invisible on ultrasonography

Autor: Kazuteru Monden, Shinya Asami, Kyo Sasaki, Norihisa Takakura, Kanyu Nakano, Mayu Uka, Masayoshi Hioki, Kazuhisa Yabushita, Toru Ueki, Satoshi Ohno, Tsuyoshi Hyodo, Kousaku Sakaguchi, Hiroshi Sadamori

Publikováno v: Asian Journal of Endoscopic Surgery. 10:100-103

Introduction The intra-operative detection of hepatocellular carcinoma (HCC) by ultrasonography is indispensable for laparoscopic partial hepatectomy. However, it is occasionally difficult to localize an HCC on an ultrasound in chronic liver disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3aaaa4ea059f2d704ad61d4a9c736099
https://doi.org/10.1111/ases.12321