Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kynon J M, Benjamin"'
Autor:
Kynon J. M. Benjamin, Ria Arora, Arthur S. Feltrin, Geo Pertea, Hunter H. Giles, Joshua M. Stolz, Laura D’Ignazio, Leonardo Collado-Torres, Joo Heon Shin, William S. Ulrich, Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger, Apuã C. M. Paquola, Jennifer A. Erwin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Schizophrenia is a complex neuropsychiatric disorder with sexually dimorphic features, including differential symptomatology, drug responsiveness, and male incidence rate. Prior large-scale transcriptome analyses for sex differences in schiz
Externí odkaz:
https://doaj.org/article/47464cd135894227b475555e891742ed
Autor:
Tomoyo Sawada, André Barbosa, Bruno Araujo, Alejandra E. McCord, Laura D’Ignazio, Kynon J. M. Benjamin, Arthur Feltrin, Ria Arora, Anna C. Brandtjen, Joel E. Kleinman, Thomas M. Hyde, Daniel R. Weinberger, Apuā C. M. Paquola, Jennifer A. Erwin
Schizophrenia (SCZ) is a brain disorder originating during neurodevelopment with complex genetic and environmental etiologies. Despite decades of clinical evidence of altered striatal function in affected patients, its cellular and molecular underpin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2dc2d603cf397a640ae9ce965d09afd
https://doi.org/10.1101/2022.05.26.493589
https://doi.org/10.1101/2022.05.26.493589
Autor:
Laura D’Ignazio, Ricardo S. Jacomini, Bareera Qamar, Kynon J. M. Benjamin, Ria Arora, Tomoyo Sawada, Taylor A. Evans, Kenneth E. Diffenderfer, Aimee R. Pankonin, William T. Hendriks, Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger, D. Cristopher Bragg, Apua C. M. Paquola, Jennifer A. Erwin
Publikováno v:
eneuro. 9:ENEURO.0129-22.2022
X-linked dystonia-parkinsonism (XDP) is an inherited, X-linked, adult-onset movement disorder characterized by degeneration in the neostriatum. No therapeutics alter disease progression. The mechanisms underlying regional differences in degeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64bcfab4e23635d05f9aeb168aa126fb
https://doi.org/10.1523/eneuro.0129-22.2022
https://doi.org/10.1523/eneuro.0129-22.2022
Autor:
Kynon J M, Benjamin, Qiang, Chen, Andrew E, Jaffe, Joshua M, Stolz, Leonardo, Collado-Torres, Louise A, Huuki-Myers, Emily E, Burke, Ria, Arora, Arthur S, Feltrin, André Rocha, Barbosa, Eugenia, Radulescu, Giulio, Pergola, Joo Heon, Shin, William S, Ulrich, Amy, Deep-Soboslay, Ran, Tao, Thomas M, Hyde, Joel E, Kleinman, Jennifer A, Erwin, Daniel R, Weinberger
Publikováno v:
Nature neuroscience. 25(11)
Most studies of gene expression in the brains of individuals with schizophrenia have focused on cortical regions, but subcortical nuclei such as the striatum are prominently implicated in the disease, and current antipsychotic drugs target the striat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69cc52a10dea143e827a5e3c4eb13325
https://pubmed.ncbi.nlm.nih.gov/36319771
https://pubmed.ncbi.nlm.nih.gov/36319771
Autor:
Tomoyo Sawada, Kynon J. M. Benjamin, Noriko Fujimori-Tonou, Kaori Tanaka, Jennifer A. Erwin, Apuã C. M. Paquola, Thomas E. Chater, Tadafumi Kato, Yukiko Goda, Yohei Sasagawa, Mika Yoshimura, Itoshi Nikaido
Publikováno v:
Molecular Psychiatry
Despite extensive genetic and neuroimaging studies, detailed cellular mechanisms underlying schizophrenia and bipolar disorder remain poorly understood. Recent progress in single-cell RNA sequencing (scRNA-seq) technologies enables identification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8504accba346d2c9264281f5e6e2b697
https://pubmed.ncbi.nlm.nih.gov/32764691
https://pubmed.ncbi.nlm.nih.gov/32764691