Výsledky vyhledávání - "Kymberley L. Sutton"

Inhibition of Integrin-Linked Kinase by a Selective Small Molecule Inhibitor, QLT0254, Inhibits the PI3K/PKB/mTOR, Stat3, and FKHR Pathways and Tumor Growth, and Enhances Gemcitabine-Induced Apoptosis in Human Orthotopic Primary Pancreatic Cancer Xenografts

Autor: David W. Hedley, Kymberley L. Sutton, Jeffery J. Wheeler, Cindy Y.F. Yau

Publikováno v: Cancer Research. 65:1497-1504

Integrin-linked kinase (ILK) couples integrins and growth factors to downstream signaling pathways involving phosphatidylinositol 3-kinase, protein kinase B/Akt (PKB/Akt), and glycogen synthase kinase-3β. The anticancer effects of ILK inhibitor QLT0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d1cc5ba707853d6f2948ff19c6f0da
https://doi.org/10.1158/0008-5472.can-04-2940

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