Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kym Eden"'
Autor:
Ryan J. Morris, Cait E. MacPhee, Juraj Szavits-Nossan, Jason M. D. Kalapothakis, Sam Covill, Perdita E. Barran, Sean Tabor, Rosalind J. Allen, Kym Eden, Jay Gillam
Publikováno v:
Kalapothakis, J M D, Morris, R, Szavits-Nossan, J, Eden, K, Covill, S, Tabor, S, Gillam, J, Barran, P E, Allen, R J & MacPhee, C E 2015, ' A Kinetic Study of Ovalbumin Fibril Formation : The Importance of Fragmentation and End-Joining ', Biophysical Journal, vol. 108, no. 9, pp. 2300-2311 . https://doi.org/10.1016/j.bpj.2015.03.021
The ability to control the morphologies of biomolecular aggregates is a central objective in the study of self-assembly processes. The development of predictive models offers the surest route for gaining such control. Under the right conditions, prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477403d6560454d7970b9b706a8a12c3
https://www.bib.irb.hr/771543
https://www.bib.irb.hr/771543
Publikováno v:
Eden, K, Morris, R, Gillam, J, MacPhee, C E & Allen, R J 2015, ' Competition between Primary Nucleation and Autocatalysis in Amyloid Fibril Self-Assembly ', Biophysical Journal, vol. 108, no. 3, pp. 632-643 . https://doi.org/10.1016/j.bpj.2014.11.3465
Kinetic measurements of the self-assembly of proteins into amyloid fibrils are often used to make inferences about molecular mechanisms. In particular, the lag time—the quiescent period before aggregates are detected—is often found to scale with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8624e5d9097175ee4e60033344432f
https://pubmed.ncbi.nlm.nih.gov/25650930
https://pubmed.ncbi.nlm.nih.gov/25650930
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2013, 4, pp.1891. ⟨10.1038/ncomms2909⟩
Nature communications
Nature Communications, Nature Publishing Group, 2013, 4, pp.1891. ⟨10.1038/ncomms2909⟩
Nature communications
International audience; Amyloid fibrils are self-assembled protein aggregates implicated in a number of human diseases. Fragmentation-dominated models for the self-assembly of amyloid fibrils have had important successes in explaining the kinetics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a971ac368538d83df3a837d6207254
https://doi.org/10.1038/ncomms2909
https://doi.org/10.1038/ncomms2909