Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kym Cardoza"'
Publikováno v:
Drug Metabolism Letters. 2:193-197
The great emphasis on ethical and humane treatment of animals in biomedical research has culminated in the promulgation of the rule of 3Rs - Replacement, Reduction, and Refinement. We have proposed an addition to the 3Rs - a fourth R for Recycling th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac0345331030a4cd749fed85102db9b2
https://doi.org/10.2174/187231208785425827
https://doi.org/10.2174/187231208785425827
Autor:
Liang-Shang Gan, Joanne Nguyen, Dun-Xue Mu, Suresh K. Balani, Jing-Tao Wu, Kym Cardoza, Hang Zeng, Frank W. Lee, Ping Li
Publikováno v:
Drug Metabolism and Disposition. 32:1092-1095
Single-dose pharmacokinetics of 1-aminobenzotriazole (ABT), a potent nonspecific inhibitor of cytochromes P450 (P450s), were characterized after oral administration to mice and guinea pigs at doses of 50, 100, and 150 mg/kg using serial sampling in b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c65e5301f5295edeacb4763b132ab5a
https://doi.org/10.1124/dmd.104.000349
https://doi.org/10.1124/dmd.104.000349
Publikováno v:
Drug metabolism letters. 2(3)
The great emphasis on ethical and humane treatment of animals in biomedical research has culminated in the promulgation of the rule of 3Rs - Replacement, Reduction, and Refinement. We have proposed an addition to the 3Rs - a fourth R for Recycling th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ed3e0d2729bcc7ed5262c8460fe4f03
https://pubmed.ncbi.nlm.nih.gov/19356093
https://pubmed.ncbi.nlm.nih.gov/19356093
Autor:
Vinita Uttamsingh, Mark G. Qian, Gerald T. Miwa, Liang-Shang Gan, Kym Cardoza, Sandeepraj Pusalkar, Ron Huang, Suresh K. Balani, Jing-Tao Wu, Wei Yin, Chuang Lu, Ping Li, Frank W. Lee, Hua Yang, Jason Labutti, Cindy Q. Xia, Nelamangala Nagaraja, J. Scott Daniels
Publikováno v:
Biotechnology: Pharmaceutical Aspects ISBN: 9780387340562
Efficacy and safety are the two key elements in the drug discovery and development processes. The primary goal for pharmaceutical research companies is to identify and manufacture therapeutic agents that are safe and efficacious for patients. In prin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b24a912dc8ab45e4db7aac8a219ab9fa
https://doi.org/10.1007/978-0-387-44961-6_4
https://doi.org/10.1007/978-0-387-44961-6_4
Publikováno v:
Drug Metabolism Reviews. Aug2006 Supplement 2, Vol. 38, p1-258. 258p.
Publikováno v:
International Journal of Toxicology (Sage); Jan2012, Vol. 31 Issue 1, p97-126, 30p
Publikováno v:
Bioanalysis; Jun2011, Vol. 3 Issue 11, p1217-1226, 10p
Autor:
Yumin Zhang, Melissa Saylor, Shenhua Wen, Matthew Silva, Mark Rolfe, Joseph Bolen, Craig Muir, Corinne Reimer, Sudeep Chandra
Publikováno v:
Molecular Imaging & Biology; Sep2006, Vol. 8 Issue 5, p300-308, 9p
Publikováno v:
Drug Metabolism Reviews. Aug2006 Supplement 2, Vol. 38, p1-258. 1p.
Drug discovery and development is a very complex, costly, and ti- consuming process. Because of the uncertainties associated with predicting the pharmacological effects and the toxicity characteristics of new chemical entities in man, their clinical