Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kylie M Drake"'
Autor:
Micheala A. Aldred, Chris Jones, Vicki Huff, Jeffrey Dome, Paul Grundy, Kathy Pritchard-Jones, Manfred Gessler, Jenny Wegert, Phyllis Harbor, Rachael Natrajan, E. Cristy Ruteshouser, Kylie M. Drake
Supplementary Data from Loss of Heterozygosity at 2q37 in Sporadic Wilms' Tumor: Putative Role for miR-562
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660cda499ca9a86e63ef7f8e275906a8
https://doi.org/10.1158/1078-0432.22440630.v1
https://doi.org/10.1158/1078-0432.22440630.v1
Autor:
Micheala A. Aldred, Chris Jones, Vicki Huff, Jeffrey Dome, Paul Grundy, Kathy Pritchard-Jones, Manfred Gessler, Jenny Wegert, Phyllis Harbor, Rachael Natrajan, E. Cristy Ruteshouser, Kylie M. Drake
Purpose: Wilms' tumor is a childhood cancer of the kidney with an incidence of ∼1 in 10,000. Cooccurrence of Wilms' tumor with 2q37 deletion syndrome, an uncommon constitutional chromosome abnormality, has been reported previously in three children
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50aac619f78a1cf5567f81a9d8aa5410
https://doi.org/10.1158/1078-0432.c.6517932
https://doi.org/10.1158/1078-0432.c.6517932
Publikováno v:
Hemoglobin. 44:297-301
We report the identification of a large deletion of the α-globin gene cluster, which removed both HBA2 and HBA1 and included the region from HBZ to HBQ1 on chromosome 16 (16p13.3). The α0-thalassemia (α0-thal) deletion was discovered in an Indian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b77e5b5d762b912a2aab6a176c19c0e
https://doi.org/10.1080/03630269.2020.1797774
https://doi.org/10.1080/03630269.2020.1797774
Autor:
Tony R. Merriman, Amanda Phipps-Green, Richard Roxburgh, Hannah A Reid, Mark P. Simpson, P. Alan Barber, Nicholas Child, Eoin Mulroy, Murray Cadzow, Shilpan G. Patel, Kylie M Drake, Marilyn E. Merriman, Neil E Anderson, Christina M Buchanan
Publikováno v:
Movement disorders : official journal of the Movement Disorder SocietyReferences. 36(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bedfa703e8cd0ce505771b3ecd5f18
https://pubmed.ncbi.nlm.nih.gov/34159639
https://pubmed.ncbi.nlm.nih.gov/34159639
Publikováno v:
Hemoglobin. 44(4)
We report the identification of a large deletion of the α-globin gene cluster, which removed both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12d3fd1301e007a6877d61d5883a3319
https://pubmed.ncbi.nlm.nih.gov/32722952
https://pubmed.ncbi.nlm.nih.gov/32722952
Autor:
Kewal Asosingh, Chiara Federici, Micheala A. Aldred, Heng T. Duong, Serpil C. Erzurum, Kylie M. Drake, Suzy A. A. Comhair
Publikováno v:
Pulmonary Circulation
Pulmonary vascular remodeling, including proliferation and migration of pulmonary artery endothelial cells (PAEC), is a pathologic hallmark of pulmonary arterial hypertension (PAH). Multiple studies have shown evidence of increased levels of DNA dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7ff0c0aa467ab4c58848df88df2734
http://europepmc.org/articles/PMC5467930
http://europepmc.org/articles/PMC5467930
Autor:
Brittney M Hooper, Kylie M Drake, Peter B. Imrey, Basabi Maitra, Micheala A. Aldred, Jane Reese Koç, Sarah M. Planchon, Karen Lingas, Hillard M. Lazarus, R. M. Fox, Jeffrey A. Cohen
Publikováno v:
Multiple Sclerosis Journal-Experimental, Translational and Clinical
Background Multiple sclerosis is an inflammatory, neurodegenerative disease of the central nervous system for which therapeutic mesenchymal stem cell transplantation is under study. Published experience of culture-expanding multiple sclerosis patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dad7a0490622e38a2ee3c8c15cc36fe
https://pubmed.ncbi.nlm.nih.gov/29623216
https://pubmed.ncbi.nlm.nih.gov/29623216
Autor:
Janine Mary Wilkinson, Nicholas W. Morrell, Paul D. Upton, Kylie M Drake, Mark L. Ormiston, Lai Ming Yung, Stephen D Moore, Matthias Mueller, Stefan Gräf, Lu Long, Rajiv D. Machado, Mark Southwood, Bernd Kinzel, Micheala A. Aldred, Xudong Yang, Paul B. Yu
Publikováno v:
Nature medicine
Genetic evidence implicates the loss of bone morphogenetic protein type II receptor (BMPR-II) signaling in the endothelium as an initiating factor in pulmonary arterial hypertension (PAH). However, selective targeting of this signaling pathway using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5cbf4c05045803c098c329dba4172f
Autor:
Serpil C. Erzurum, Christina Rigelsky, Kylie M. Drake, Suzy A.A. Comhair, Sirena L. Meade, Micheala A. Aldred, Lauren N. McNelly, Chiara Federici
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 192:219-228
Rationale: Pulmonary arterial hypertension (PAH) is a serious lung condition characterized by vascular remodeling in the precapillary pulmonary arterioles. We and others have demonstrated chromosomal abnormalities and increased DNA damage in PAH lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0290f813568687dc25a3d39c5cbbf8
https://doi.org/10.1164/rccm.201411-2128oc
https://doi.org/10.1164/rccm.201411-2128oc
Autor:
Mark Toshner, Benjamin J. Dunmore, Paul D. Upton, Kylie M. Drake, Micheala A. Aldred, Nicholas W. Morrell
Publikováno v:
Human Molecular Genetics
Pulmonary arterial hypertension (PAH) is characterized by dysregulated pulmonary artery endothelial cell (PAEC) proliferation, apoptosis and permeability. Loss-of-function mutations in the bone morphogenetic protein receptor type-II (BMPR-II) are the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9aac67d07bc2ef696cca66f1c683cbc
https://doi.org/10.1093/hmg/ddt216
https://doi.org/10.1093/hmg/ddt216