Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Kylee J Duberstein"'
Autor:
Sarah L. Schantz, Sydney E. Sneed, Madison M. Fagan, Morgane E. Golan, Savannah R. Cheek, Holly A. Kinder, Kylee J. Duberstein, Erin E. Kaiser, Franklin D. West
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1663 (2024)
Traumatic brain injury (TBI) is a leading cause of death and disability in pediatric patients and often results in delayed neural development and altered connectivity, leading to lifelong learning, memory, behavior, and motor function deficits. Induc
Externí odkaz:
https://doaj.org/article/f688b9fc112e4ac4bc9f03d6f2bc4749
Autor:
Madison M. Fagan, Kelly M. Scheulin, Sydney E. Sneed, Wenwu Sun, Christina B. Welch, Savannah R. Cheek, Erin E. Kaiser, Qun Zhao, Kylee J. Duberstein, Franklin D. West
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 247 (2024)
Pediatric traumatic brain injury (TBI) often induces significant disability in patients, including long-term motor deficits. Early detection of injury severity is key in determining a prognosis and creating appropriate intervention and rehabilitation
Externí odkaz:
https://doaj.org/article/c23c880b7d2942329c056c531ece00e9
Autor:
Madison M. Fagan, Christina B. Welch, Kelly M. Scheulin, Sydney E. Sneed, Julie H. Jeon, Morgane E. Golan, Savannah R. Cheek, Deborah A. Barany, Georg Oeltzschner, Todd R. Callaway, Qun Zhao, Hea Jin Park, Jeferson M. Lourenco, Kylee J. Duberstein, Franklin D. West
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Pediatric traumatic brain injury (TBI) is a leading cause of death and disability in children. Due to bidirectional communication between the brain and gut microbial population, introduction of key gut bacteria may mitigate critical TBI-induced secon
Externí odkaz:
https://doaj.org/article/891e7dc5bd3149b0b071b4984dff329a
Autor:
Julie H. Jeon, Erin E. Kaiser, Elizabeth S. Waters, Xueyuan Yang, Jeferson M. Lourenco, Madison M. Fagan, Kelly M. Scheulin, Sydney E. Sneed, Soo K. Shin, Holly A. Kinder, Anil Kumar, Simon R. Platt, Jeongyoun Ahn, Kylee J. Duberstein, Michael J. Rothrock, Todd R. Callaway, Jin Xie, Franklin D. West, Hea Jin Park
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Impaired gut homeostasis is associated with stroke often presenting with leaky gut syndrome and increased gut, brain, and systemic inflammation that further exacerbates brain damage. We previously reported that intracisternal administration
Externí odkaz:
https://doaj.org/article/6d469ec2e68b470295666853b023f23d
Autor:
Elizabeth S. Waters, Erin E. Kaiser, Xueyuan Yang, Madison M. Fagan, Kelly M. Scheulin, Julie H. Jeon, Soo K. Shin, Holly A. Kinder, Anil Kumar, Simon R. Platt, Kylee J. Duberstein, Hea Jin Park, Jin Xie, Franklin D. West
Publikováno v:
IBRO Neuroscience Reports, Vol 10, Iss , Pp 18-30 (2021)
Background: The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a
Externí odkaz:
https://doaj.org/article/d28f059093814129a866cebfb77646c7
Autor:
Julie Heejin Jeon, Jeferson M. Lourenco, Madison M. Fagan, Christina B. Welch, Sydney E. Sneed, Stephanie Dubrof, Kylee J. Duberstein, Todd R. Callaway, Franklin D. West, Hea Jin Park
Publikováno v:
Brain Sciences, Vol 12, Iss 8, p 1111 (2022)
Dynamic changes in the oral microbiome have gained attention due to their potential diagnostic role in neurological diseases such as Alzheimer’s disease and Parkinson’s disease. Traumatic brain injury (TBI) is a leading cause of death and disabil
Externí odkaz:
https://doaj.org/article/27a6e5dab53748289ebd1a7a6b7330c1
Autor:
Sydney E. Sneed, Kelly M. Scheulin, Erin E. Kaiser, Madison M. Fagan, Brian J. Jurgielewicz, Elizabeth S. Waters, Samantha E. Spellicy, Kylee J. Duberstein, Simon R. Platt, Emily W. Baker, Steven L. Stice, Holly A. Kinder, Franklin D. West
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
The Stroke Therapy Academic Industry Roundtable (STAIR) has recommended that novel therapeutics be tested in a large animal model with similar anatomy and physiology to humans. The pig is an attractive model due to similarities in brain size, organiz
Externí odkaz:
https://doaj.org/article/33722d55cfbf4dc5af73b07d776604a2
Autor:
Xueyuan Yang, Soo K. Shin, Jin Xie, Kylee J. Duberstein, Madison M. Fagan, Simon R. Platt, Kelly M. Scheulin, Erin E. Kaiser, Holly A. Kinder, Elizabeth S. Waters, Julie Jeon, Franklin D. West, Anil Kumar, Hea Jin Park
Publikováno v:
IBRO Neuroscience Reports
IBRO Neuroscience Reports, Vol 10, Iss, Pp 18-30 (2021)
IBRO Neuroscience Reports, Vol 10, Iss, Pp 18-30 (2021)
Background The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a p
Autor:
Julie H. Jeon, Jeferson Lourenco, Madison M. Fagan, Christina B. Welch, Sydney E. Sneed, Kylee J. Duberstein, Todd R. Callaway, Franklin D. West, Hea Jin Park
Publikováno v:
The FASEB Journal. 36
Autor:
Erin E Kaiser, Elizabeth S Waters, Xueyuan Yang, Madison M Fagan, Kelly M Scheulin, Sydney E Sneed, Savannah R Cheek, Julie Heejin Jeon, Soo K Shin, Holly A Kinder, Anil Kumar, Simon R Platt, Kylee J Duberstein, Hea Jin Park, Jin Xie, Franklin D West
Publikováno v:
Stem cells translational medicine. 11(10)
Induced pluripotent stem cell-derived neural stem cells (iNSCs) are a multimodal stroke therapeutic that possess neuroprotective, regenerative, and cell replacement capabilities post-ischemia. However, long-term engraftment and efficacy of iNSCs is l