Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kyle W. Selcer"'
Publikováno v:
Liver Research, Vol 1, Iss 1, Pp 63-69 (2017)
Background and Aim: Sulfotransferase (SULT)-mediated sulfation and steroid sulfatase (STS)-mediated desulfation represent two critical mechanisms that regulate the chemical and functional homeostasis of endogenous and exogenous molecules. STS catalyz
Externí odkaz:
https://doaj.org/article/f0bc50a8a13a482da9aab4521c663e41
Publikováno v:
Steroids. 191:109163
Curcumin is a phytochemical derived from the spice turmeric that is reported to have therapeutic effects. We are studying the enzyme steroid sulfatase (STS), which removes the sulfate group from inactive steroid hormones in peripheral tissues and we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4638baa15ae683d5e03fd01f2e07d6
https://doi.org/10.1016/j.steroids.2022.109163
https://doi.org/10.1016/j.steroids.2022.109163
Autor:
Kyle W. Selcer, Yang Xie, Hongbing Wang, Meishu Xu, Samuel M. Poloyac, Ye Feng, Linhao Li, Chaohui Yu, Chengjiang Li, Wen Xie, Patrick J. Oberly, Fengqin Dong
Publikováno v:
J Biol Chem
Conjugated equine estrogens (CEEs), whose brand name is Premarin, are widely used as a hormone-replacement therapy (HRT) drug to manage postmenopausal symptoms in women. Extracted from pregnant mare urine, CEEs are composed of nearly a dozen estrogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac843039db4f2e57878d9380fe26073
https://doi.org/10.1074/jbc.ra119.009181
https://doi.org/10.1074/jbc.ra119.009181
Autor:
Rachel Urbano, Jade Kerr, Barathi Balasubramonian, Kyle W. Selcer, Sanjana Ojha, Mia DiFrancesco, Dylan Miller
Publikováno v:
Steroids. 174
Steroid hormones often circulate in the blood as inactive sulfated forms, such as estrone sulfate and dehydroepiandrosterone sulfate. The enzyme steroid sulfatase (STS) converts these steroids into active forms, mainly estrogens, in peripheral tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fd1a49c7b847ca15f96224ef798d8e
https://pubmed.ncbi.nlm.nih.gov/34280393
https://pubmed.ncbi.nlm.nih.gov/34280393
Autor:
Kyle W. Selcer, Wen Xie, Da Yang, Songrong Ren, Xiudong Guan, Nilesh W. Gaikwad, Weiwei Guo, Meishu Xu, Mengxi Jiang, Yuhan Bi
Publikováno v:
Endocrinology. 159:3365-3377
Steroid sulfatase (STS), a desulfating enzyme that converts steroid sulfates to hormonally active steroids, plays an important role in the homeostasis of sex hormones. STS is expressed in the adipose tissue of both male and female mice, but the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4accf74d9a6595f04ae8860c9c3fe50
https://doi.org/10.1210/en.2018-00531
https://doi.org/10.1210/en.2018-00531
Publikováno v:
Copeia. 104:921-929
Vitellogenin (VTG) is an egg yolk-precursor protein that serves as a nutrient source for developing embryos in oviparous vertebrates. The hormonal control of this protein has been studied in a variety of taxa, but details about the dynamics of this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b55f30caa3d3c99885b4c41b28717e
https://doi.org/10.1643/cp-16-393
https://doi.org/10.1643/cp-16-393
Autor:
Matthew C. Cave, Mengxi Jiang, Xiuhui Zhang, Song Li, Jiang Li, Wen Xie, Yan Guo, Natasha J. Dias, Ulrich M. Zanger, Jinhan He, Wenxin Qin, Marcus Klein, Qiujin Shen, Kyle W. Selcer, Mohammad K. Mohammad, Nilesh W. Gaikwad
Publikováno v:
Journal of Hepatology. 64:44-52
Background & Aims Chronic inflammatory liver diseases are associated with estrogen excess and feminization in men, which is thought to be due to compromised liver function to break down estrogens. The goal of this study is to determine whether the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22d18ae595afc1510546aef41eed4ff
https://doi.org/10.1016/j.jhep.2015.07.022
https://doi.org/10.1016/j.jhep.2015.07.022
Autor:
Vanessa Vélez-Rivera, Kyle W. Selcer, Casey M. Holliday, Ying Yang, Frederick S. vom Saal, Sharon L. Deem, Caitlin M. Jandegian, Diane K. Nicks, Cheryl S. Rosenfeld, Ramji K. Bhandari, Donald E. Tillitt, Dawn K. Holliday
Publikováno v:
General and Comparative Endocrinology. 216:77-85
Environmental chemicals can disrupt endocrine signaling and adversely impact sexual differentiation in wildlife. Bisphenol A (BPA) is an estrogenic chemical commonly found in a variety of habitats. In this study, we used painted turtles (Chrysemys pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f430d96f9c34ac3530f2efeab45063c
https://doi.org/10.1016/j.ygcen.2015.04.003
https://doi.org/10.1016/j.ygcen.2015.04.003
Publikováno v:
Liver Research, Vol 1, Iss 1, Pp 63-69 (2017)
Background and Aim: Sulfotransferase (SULT)-mediated sulfation and steroid sulfatase (STS)-mediated desulfation represent two critical mechanisms that regulate the chemical and functional homeostasis of endogenous and exogenous molecules. STS catalyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca4ac7272ed82828523b9c097f286b0
https://pubmed.ncbi.nlm.nih.gov/29130021
https://pubmed.ncbi.nlm.nih.gov/29130021
Autor:
Vanessa Vélez-Rivera, Frederick S. vom Saal, Donald E. Tillitt, Diane K. Nicks, Cheryl S. Rosenfeld, Dawn K. Holliday, Ying Yang, Ramji K. Bhandari, Sharon L. Deem, Caitlin M. Jandegian, Casey M. Holliday, Kyle W. Selcer
Publikováno v:
General and comparative endocrinology. 247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0186ed45fddbcbf44ad4d0bd88c5ba42
https://pubmed.ncbi.nlm.nih.gov/25863134
https://pubmed.ncbi.nlm.nih.gov/25863134