Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kyle W. Gheres"'
Autor:
Fan Li, Jazlyn Gallego, Natasha N. Tirko, Jenna Greaser, Derek Bashe, Rudra Patel, Eric Shaker, Grace E. Van Valkenburg, Alanoud S. Alsubhi, Steven Wellman, Vanshika Singh, Camila Garcia Padilla, Kyle W. Gheres, John I. Broussard, Roger Bagwell, Maureen Mulvihill, Takashi D. Y. Kozai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Microglia are important players in surveillance and repair of the brain. Implanting an electrode into the cortex activates microglia, produces an inflammatory cascade, triggers the foreign body response, and opens the blood-brain barrier. Th
Externí odkaz:
https://doaj.org/article/91f91a8693bf47b1a4a20e5cbc4a9141
Autor:
Fan Li, Jazlyn Gallego, Natasha N. Tirko, Jenna Greaser, Derek Bashe, Rudra Patel, Eric Shaker, Grace E. Van Valkenburg, Alanoud S. Alsubhi, Steven Wellman, Vanshika Singh, Camila Garcia Padilla, Kyle W. Gheres, John I. Broussard, Roger Bagwell, Maureen Mulvihill, Takashi D. Y. Kozai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/59be283059914ffd9ffee46ff4cf0cfe
Autor:
Kyle W. Gheres, Hayreddin S. Ünsal, Xu Han, Qingguang Zhang, Kevin L. Turner, Nanyin Zhang, Patrick J. Drew
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract In the adult sensory cortex, increases in neural activity elicited by sensory stimulation usually drive vasodilation mediated by neurovascular coupling. However, whether neurovascular coupling is the same in neonatal animals as adults is con
Externí odkaz:
https://doaj.org/article/208c7d5adcdb42ec909dfc8de9b45f87
Autor:
Qingguang Zhang, Morgane Roche, Kyle W. Gheres, Emmanuelle Chaigneau, Ravi T. Kedarasetti, William D. Haselden, Serge Charpak, Patrick J. Drew
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Understanding mechanisms of cerebral oxygen regulation is critical for healthy brain function. Here the authors show that respiration is a key modulator of cerebral oxygenation, which will be helpful in better resolving neurally-generated functional
Externí odkaz:
https://doaj.org/article/149e92e727f04b9bbf6658abd9a6c2e9
Autor:
Michelle C. Stone, Kavitha Rao, Kyle W. Gheres, Seahee Kim, Juan Tao, Caroline La Rochelle, Christin T. Folker, Nina T. Sherwood, Melissa M. Rolls
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1340-1350 (2012)
Axon regeneration allows neurons to repair circuits after trauma; however, most of the molecular players in this process remain to be identified. Given that microtubule rearrangements have been observed in injured neurons, we tested whether microtubu
Externí odkaz:
https://doaj.org/article/bd59bc15c0f749f1a5255fbb5f23ec60
Autor:
Qingqing Zhang, Samuel R Cramer, Zilu Ma, Kevin L Turner, Kyle W Gheres, Yikang Liu, Patrick J Drew, Nanyin Zhang
Publikováno v:
Cereb Cortex
A notorious issue of task-based functional magnetic resonance imaging (fMRI) is its large cross-trial variability. To quantitatively characterize this variability, the blood oxygenation level-dependent (BOLD) signal can be modeled as a linear summati
Autor:
Qingguang Zhang, Morgane Roche, Kyle W. Gheres, Emmanuelle Chaigneau, William D. Haselden, Ravi T. Kedarasetti, Serge Charpak, Patrick J. Drew
Publikováno v:
Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN).
Behavioral and physiological monitoring for awake neurovascular coupling experiments: a how-to guide
Publikováno v:
Neurophotonics
Significance: Functional brain imaging in awake animal models is a popular and powerful technique that allows the investigation of neurovascular coupling (NVC) under physiological conditions. However, ubiquitous facial and body motions (fidgeting) ar
Autor:
Emmanuelle Chaigneau, Kyle W. Gheres, William D. Haselden, Serge Charpak, Morgane Roche, Qingguang Zhang, Patrick J. Drew, Ravi Teja Kedarasetti
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
In the brain, increased neural activity is correlated with increases of cerebral blood flow and tissue oxygenation. However, how cerebral oxygen dynamics are controlled in the behaving animal remains unclear. We investigated to what extent cerebral o
Autor:
Shubham Mirg, Haoyang Chen, Kevin L. Turner, Kyle W. Gheres, Jinyun Liu, Bruce J. Gluckman, Patrick J. Drew, Sri-Rajasekhar Kothapalli
Publikováno v:
Optics Letters. 47:1121
Optical resolution photoacoustic microscopy (OR-PAM) can map the cerebral vasculature at capillary-level resolution. However, the OR-PAM setup’s bulky imaging head makes awake mouse brain imaging challenging and inhibits its integration with other