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pro vyhledávání: '"Kyle T. Wagner"'
Autor:
C. Tilden Hagan, Cameron Bloomquist, Samuel Warner, Nicole M. Knape, Isaiah Kim, Hayley Foley, Kyle T. Wagner, Sue Mecham, Joseph DeSimone, Andrew Z. Wang
Publikováno v:
J Control Release
Surgery is an important treatment for cancer; however, local recurrence following macroscopically-complete resection is common and a significant cause of morbidity and mortality. Systemic chemotherapy is often employed as an adjuvant therapy to preve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6f0de47a277288ab17b595d699af98
https://europepmc.org/articles/PMC9373975/
https://europepmc.org/articles/PMC9373975/
Autor:
Mahdi M. Abu-Omar, Julian E. Fuchs, Judith A. Ronau, Isaac R. Corn, Lake N. Paul, Kyle T. Wagner, Chittaranjan Das, Klaus R. Liedl
Publikováno v:
European Biophysics Journal. 42:691-708
Phenylalanine hydroxylase (PAH) is a non-heme iron enzyme that catalyzes oxidation of phenylalanine to tyrosine, a reaction that must be kept under tight regulatory control. Mammalian PAH has a regulatory domain in which binding of the substrate lead