Výsledky vyhledávání - "Kyle T Pfaffenbach"

Akademický článek

Cardiometabolic plasticity in response to a short-term diet and exercise intervention in young Hispanic and nonHispanic white adults.

Autor: Stacy L Schmidt, Matthew S Hickey, Kathryn M Koblenz, Holly Klamer, Maria F Botero, Kyle T Pfaffenbach, Michael J Pagliassotti, Christopher L Melby

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e16987 (2011)

BACKGROUND: Young adult Mexican Americans (MA) exhibit lower insulin sensitivity (Si) than nonHispanic whites (NHW), even when controlling for fitness and adiposity. It is unclear if MA are as responsive to the same lifestyle intervention as NHW. OBJ

Externí odkaz: https://doaj.org/article/e16e20d7fdd84f4aa6f17cb9720c5e80

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C-reactive protein does not impair insulin suppression of glucose release in primary hepatocytes

Autor: Yuren Wei, Dong Wang, Flannery Ellis, Christopher L. Gentile, Michael J. Pagliassotti, Angela M. Nivala, Kyle T. Pfaffenbach

Publikováno v: Nutrition, Metabolism and Cardiovascular Diseases. 22:115-119

Recent studies have suggested that CRP may interfere with insulin signaling in skeletal muscle and endothelial cells. The aim of this study was to determine whether highly purified CRP increased the rate of glucose appearance in primary hepatocytes i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f1c7bf319c1b401c10576b9813ab84
https://doi.org/10.1016/j.numecd.2010.04.013

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Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease

Autor: Yuren Wei, David J. Orlicky, Kenneth N. Maclean, Kyle T. Pfaffenbach, Angela M. Nivala, Hua Jiang, Christopher L. Gentile, Dennis R. Petersen, Dong Wang, Jon C. Gonzales, Michael J. Pagliassotti

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 301:R1710-R1722

The incidence of obesity is now at epidemic proportions and has resulted in the emergence of nonalcoholic fatty liver disease (NAFLD) as a common metabolic disorder that can lead to liver injury and cirrhosis. Excess sucrose and long-chain saturated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e18f6a209d927425d1cda4235ef1c45
https://doi.org/10.1152/ajpregu.00677.2010

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Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin

Autor: Yuren Wei, Dong Wang, Michael J. Pagliassotti, R. Cox, Christopher L. Gentile, Kyle T. Pfaffenbach

Publikováno v: Molecular and Cellular Biochemistry. 344:99-107

Excess fatty acids are closely associated with metabolic dysfunction. The deleterious effects of fatty acids relate, in part, to their ability to up-regulate proinflammatory cytokines and propagate a state of systemic inflammation. CREBh is a recentl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f748e11b3a441212027a4f51f0ff3938
https://doi.org/10.1007/s11010-010-0533-3

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Rapamycin Inhibits Postprandial-Mediated X-Box-Binding Protein-1 Splicing in Rat Liver

Autor: Flannery Ellis, Angela M. Nivala, Yuren Wei, Dong Wang, Michael J. Pagliassotti, Kyle T. Pfaffenbach, Lauren Reese

Publikováno v: The Journal of Nutrition. 140:879-884

Recent studies have linked the unfolded protein response (UPR), in particular the inositol-requiring, endoplasmic reticulum-to-nucleus signaling protein 1α (IRE1α)-X-box-binding protein-1 (XBP1) branch of the UPR, to the regulation of lipogenesis a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3bab6229955ba536637d9ae64d3d7f4
https://doi.org/10.3945/jn.109.119883

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Cardiometabolic plasticity in response to a short-term diet and exercise intervention in young Hispanic and nonHispanic white adults

Autor: Holly Klamer, Michael J. Pagliassotti, Christopher L. Melby, Matthew S. Hickey, Kyle T. Pfaffenbach, Kathryn M. Koblenz, Stacy L. Schmidt, Maria F. Botero

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e16987 (2011)
PLoS ONE

Background Young adult Mexican Americans (MA) exhibit lower insulin sensitivity (Si) than nonHispanic whites (NHW), even when controlling for fitness and adiposity. It is unclear if MA are as responsive to the same lifestyle intervention as NHW. Obje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a29763ece8ff0e84b98dbd1fa9bbed
http://europepmc.org/articles/PMC3043099?pdf=render

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Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death

Autor: Christopher L. Gentile, Yuren Wei, Kyle T. Pfaffenbach, Michael J. Pagliassotti, Dong Wang, Angela M. Nivala

Prolonged endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) have been linked to apoptosis via several mechanisms, including increased expression of C/EBP homologous protein ( Chop). Increased long-chain fatty aci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fa6076ec4a343d03cf2b69888e5a42
https://europepmc.org/articles/PMC2867372/

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