Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kyle S, Martin"'
Autor:
Catherine C Henry, Kyle S Martin, Bridget B Ward, Geoffrey G Handsfield, Shayn M Peirce, Silvia S Blemker
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183853 (2017)
Duchenne muscular dystrophy (DMD) is a progressive degenerative disease that results in fibrosis and atrophy of muscles. The main cause of death associated with DMD is failure of the diaphragm. The diaphragm is a dome-shaped muscle with a fiber micro
Externí odkaz:
https://doaj.org/article/df96e367d22e4bddb56279640e273edb
Publikováno v:
American Journal of Physiology-Cell Physiology. 318:C818-C830
Tryptophan catabolism through the kynurenine pathway generates a variety of bioactive metabolites. Physical exercise can modulate kynurenine pathway metabolism in skeletal muscle and thus change the concentrations of select compounds in peripheral ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9f0c0ef48e6c5a146a8586f03f5cc2
https://doi.org/10.1152/ajpcell.00580.2019
https://doi.org/10.1152/ajpcell.00580.2019
Autor:
Jarrod A. Call, Borna Mehrad, Victor E. Laubach, Kyle S. Martin, Russell P. Bowler, Carolina A. Galarreta, Jean A. Donet, Zhongmin Du, Ashish Sharma, Zhen Yan, Alexander L. Klibanov, Vitor A. Lira, Mei Zhang, Mitsuharu Okutsu, Shayn M. Peirce, Brian H. Annex, Jiuzhi Zhang, Xiaobin Chen, Jie Cai
Publikováno v:
Free Radical Biology and Medicine. 113:212-223
Multiple organ dysfunction syndrome (MODS) is a detrimental clinical complication in critically ill patients with high mortality. Emerging evidence suggests that oxidative stress and endothelial activation (induced expression of adhesion molecules) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2e0e9a79499f7b3902105d6257e4da
https://doi.org/10.1016/j.freeradbiomed.2017.09.029
https://doi.org/10.1016/j.freeradbiomed.2017.09.029
Autor:
Kelley M, Virgilio, Brian K, Jones, Emily Y, Miller, Elnaz, Ghajar-Rahimi, Kyle S, Martin, Shayn M, Peirce, Silvia S, Blemker
Publikováno v:
Annals of biomedical engineering. 49(2)
Duchenne muscular dystrophy is a pro-fibrotic, muscle wasting disease. Reducing fibrosis is a potential therapeutic target; however, its effect on muscle regeneration is not fully understood. This study (1) used an agent-based model to predict the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa0337b25077e3cfd0825b742a3313b7
https://pubmed.ncbi.nlm.nih.gov/32748106
https://pubmed.ncbi.nlm.nih.gov/32748106
Publikováno v:
Cells Tissues Organs. 202:250-266
Skeletal muscle has an exceptional ability to regenerate and adapt following injury. Tissue engineering approaches (e.g. cell therapy, scaffolds, and pharmaceutics) aimed at enhancing or promoting muscle regeneration from severe injuries are a promis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453fd34f43f4ecb2fec8f1a024bfead1
https://doi.org/10.1159/000443635
https://doi.org/10.1159/000443635
Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disease with no effective treatment. Multiple mechanisms are thought to contribute to muscle wasting, including increased susceptibility to contraction-induced damage, chronic inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354756b8182a66f57f5a6792506b051d
https://europepmc.org/articles/PMC6295486/
https://europepmc.org/articles/PMC6295486/
Autor:
Jarrod A. Call, Zhen Yan, Vitor A. Lira, Mitsuharu Okutsu, Mei Zhang, Kristopher H. Chain, Kyle S. Martin
Publikováno v:
Circulation: Heart Failure. 8:188-197
Background— Exercise training enhances extracellular superoxide dismutase (EcSOD) expression in skeletal muscle and elicits positive health outcomes in individuals with diabetes mellitus. The goal of this study was to determine if enhanced skeletal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321c863e7df00979863039328e7a529c
https://doi.org/10.1161/circheartfailure.114.001540
https://doi.org/10.1161/circheartfailure.114.001540
Autor:
Bridget B. Ward, Catherine C. Henry, Kyle S. Martin, Geoffrey G. Handsfield, Shayn M. Peirce, Silvia S. Blemker
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0183853 (2017)
PLoS ONE, Vol 12, Iss 9, p e0183853 (2017)
Duchenne muscular dystrophy (DMD) is a progressive degenerative disease that results in fibrosis and atrophy of muscles. The main cause of death associated with DMD is failure of the diaphragm. The diaphragm is a dome-shaped muscle with a fiber micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ec121425d8cf7796fae0a19d375e48
http://europepmc.org/articles/PMC5587283
http://europepmc.org/articles/PMC5587283
Autor:
Kyle S. Martin, Christopher D Kegelman, George J. Christ, Silvia S. Blemker, Julianna A. Passipieri, Kelley M. Virgilio, Shayn M. Peirce
Publikováno v:
Annals of biomedical engineering. 45(3)
Numerous studies have pharmacologically modulated the muscle milieu in the hopes of promoting muscle regeneration; however, the timing and duration of these interventions are difficult to determine. This study utilized a combination of in silico and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c063b2e410571adf4a5d60df0863a8
https://pubmed.ncbi.nlm.nih.gov/27718091
https://pubmed.ncbi.nlm.nih.gov/27718091
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 118(10)
Skeletal muscle is highly responsive to use. In particular, muscle atrophy attributable to decreased activity is a common problem among the elderly and injured/immobile. However, each muscle does not respond the same way. We developed an agent-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e524c6065d102c49a6b51a890775584b
https://pubmed.ncbi.nlm.nih.gov/25814637
https://pubmed.ncbi.nlm.nih.gov/25814637