Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Kyle R. Pomraning"'
Autor:
Guoliang Yuan, Shuang Deng, Jeffrey J. Czajka, Ziyu Dai, Beth A. Hofstad, Joonhoon Kim, Kyle R. Pomraning
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
CRISPR technology has revolutionized fungal genetic engineering by accelerating the pace and expanding the feasible scope of experiments in this field. Among various CRISPR-Cas systems, Cas9 and Cas12a are widely used in genetic and metabolic enginee
Externí odkaz:
https://doaj.org/article/c9c3d97444044188a7ad871bc2af7503
Autor:
Jeffrey J. Czajka, Yichao Han, Joonhoon Kim, Stephen J. Mondo, Beth A. Hofstad, AnaLaura Robles, Sajeet Haridas, Robert Riley, Kurt LaButti, Jasmyn Pangilinan, William Andreopoulos, Anna Lipzen, Juying Yan, Mei Wang, Vivian Ng, Igor V. Grigoriev, Joseph W. Spatafora, Jon K. Magnuson, Scott E. Baker, Kyle R. Pomraning
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The Lipomyces clade contains oleaginous yeast species with advantageous metabolic features for biochemical and biofuel production. Limited knowledge about the metabolic networks of the species and limited tools for genetic engineering have led to a r
Externí odkaz:
https://doaj.org/article/e4235ff99f1948b58b602ca0631e234b
Autor:
Guoliang Yuan, Jeffrey J. Czajka, Ziyu Dai, Dehong Hu, Kyle R. Pomraning, Beth A. Hofstad, Joonhoon Kim, Ana L. Robles, Shuang Deng, Jon K. Magnuson
Publikováno v:
Fungal Biology and Biotechnology, Vol 10, Iss 1, Pp 1-15 (2023)
Abstract Background Fungi have been utilized for centuries in medical, agricultural, and industrial applications. Development of systems biology techniques has enabled the design and metabolic engineering of these fungi to produce novel fuels, chemic
Externí odkaz:
https://doaj.org/article/0faa4559be34411da015d2232cf1e748
Autor:
Aivett Bilbao, Nathalie Munoz, Joonhoon Kim, Daniel J. Orton, Yuqian Gao, Kunal Poorey, Kyle R. Pomraning, Karl Weitz, Meagan Burnet, Carrie D. Nicora, Rosemarie Wilton, Shuang Deng, Ziyu Dai, Ethan Oksen, Aaron Gee, Rick A. Fasani, Anya Tsalenko, Deepti Tanjore, James Gardner, Richard D. Smith, Joshua K. Michener, John M. Gladden, Erin S. Baker, Christopher J. Petzold, Young-Mo Kim, Alex Apffel, Jon K. Magnuson, Kristin E. Burnum-Johnson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Multidimensional measurements using state-of-the-art separations and mass spectrometry provide advantages in untargeted metabolomics analyses for studying biological and environmental bio-chemical processes. However, the lack of rapid analyt
Externí odkaz:
https://doaj.org/article/824cf255ab3a47ab8c1ea26aef65e040
Autor:
Ziyu Dai, Kyle R. Pomraning, Shuang Deng, Joonhoon Kim, Kristen B. Campbell, Ana L. Robles, Beth A. Hofstad, Nathalie Munoz, Yuqian Gao, Teresa Lemmon, Marie S. Swita, Jeremy D. Zucker, Young-Mo Kim, Kristin E. Burnum-Johnson, Jon K. Magnuson
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Background Fuels and chemicals derived from non-fossil sources are needed to lessen human impacts on the environment while providing a healthy and growing economy. 3-hydroxypropionic acid (3-HP) is an important chemical building block that c
Externí odkaz:
https://doaj.org/article/8683f00131474c27bb32b907d4c7cade
Autor:
Guoliang Yuan, Song Gao, Jeffrey J. Czajka, Ziyu Dai, Kyle R. Pomraning, Rylan D. Duong, Beth A. Hofstad, Shuang Deng
Publikováno v:
Life, Vol 14, Iss 1, p 115 (2024)
Microalgae are recognized for their versatility in providing renewable energy, biopharmaceuticals, and nutraceuticals, attributed to their sustainable, renewable, and cost-effective nature. Genetic engineering has proven highly effective in enhancing
Externí odkaz:
https://doaj.org/article/154926e7af0a47a48992eded8d0c463a
Autor:
Kyle R. Pomraning, Ziyu Dai, Nathalie Munoz, Young-Mo Kim, Yuqian Gao, Shuang Deng, Teresa Lemmon, Marie S. Swita, Jeremy D. Zucker, Joonhoon Kim, Stephen J. Mondo, Ellen Panisko, Meagan C. Burnet, Bobbie-Jo M. Webb-Robertson, Beth Hofstad, Scott E. Baker, Kristin E. Burnum-Johnson, Jon K. Magnuson
Publikováno v:
Metabolic Engineering Communications, Vol 15, Iss , Pp e00203- (2022)
The global regulator LaeA controls secondary metabolism in diverse Aspergillus species. Here we explored its role in regulation of itaconic acid production in Aspergillus pseudoterreus. To understand its role in regulating metabolism, we deleted and
Externí odkaz:
https://doaj.org/article/c82712619c0643e8aca4916f9a4abde9
Autor:
Kyle R. Pomraning, James R. Collett, Joonhoon Kim, Ellen A. Panisko, David E. Culley, Ziyu Dai, Shuang Deng, Beth A. Hofstad, Mark G. Butcher, Jon K. Magnuson
Publikováno v:
Biotechnology for Biofuels, Vol 12, Iss 1, Pp 1-15 (2019)
Abstract Background Efficient and economically viable production of biofuels from lignocellulosic biomass is dependent on mechanical and chemical pretreatment and enzymatic hydrolysis of plant material. These processing steps yield simple sugars as w
Externí odkaz:
https://doaj.org/article/6a7288294f754d37b91bad653e2f07fd
Autor:
Kyle R. Pomraning, Ziyu Dai, Nathalie Munoz, Young-Mo Kim, Yuqian Gao, Shuang Deng, Joonhoon Kim, Beth A. Hofstad, Marie S. Swita, Teresa Lemmon, James R. Collett, Ellen A. Panisko, Bobbie-Jo M. Webb-Robertson, Jeremy D. Zucker, Carrie D. Nicora, Henrique De Paoli, Scott E. Baker, Kristin E. Burnum-Johnson, Nathan J. Hillson, Jon K. Magnuson
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Biological engineering of microorganisms to produce value-added chemicals is a promising route to sustainable manufacturing. However, overproduction of metabolic intermediates at high titer, rate, and yield from inexpensive substrates is challenging
Externí odkaz:
https://doaj.org/article/0ffca279396d4456b27cf621f04488ae
Autor:
Kyle R. Pomraning, Erin L. Bredeweg, Eduard J. Kerkhoven, Kerrie Barry, Sajeet Haridas, Hope Hundley, Kurt LaButti, Anna Lipzen, Mi Yan, Jon K. Magnuson, Blake A. Simmons, Igor V. Grigoriev, Jens Nielsen, Scott E. Baker
Publikováno v:
mSphere, Vol 3, Iss 6 (2018)
ABSTRACT The yeast Yarrowia lipolytica undergoes a morphological transition from yeast-to-hyphal growth in response to environmental conditions. A forward genetic screen was used to identify mutants that reliably remain in the yeast phase, which were
Externí odkaz:
https://doaj.org/article/cc463e3b48fe4a00a8aa69007f659dfd