Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kyle R. Hager"'
Autor:
Alexander Eng, Hillary S. Hayden, Christopher E. Pope, Mitchell J. Brittnacher, Anh T. Vo, Eli J. Weiss, Kyle R. Hager, Daniel H. Leung, Sonya L. Heltshe, Daniel Raftery, Samuel I. Miller, Lucas R. Hoffman, Elhanan Borenstein
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background Infants with cystic fibrosis (CF) suffer from gastrointestinal (GI) complications, including pancreatic insufficiency and intestinal inflammation, which have been associated with impaired nutrition and growth. Recent evidence iden
Externí odkaz:
https://doaj.org/article/69900369972c4aafab8be30c1ed91e63
Autor:
Maria T. Nelson, Christopher E. Pope, Robyn L. Marsh, Daniel J. Wolter, Eli J. Weiss, Kyle R. Hager, Anh T. Vo, Mitchell J. Brittnacher, Matthew C. Radey, Hillary S. Hayden, Alexander Eng, Samuel I. Miller, Elhanan Borenstein, Lucas R. Hoffman
Publikováno v:
Cell Reports, Vol 26, Iss 8, Pp 2227-2240.e5 (2019)
Summary: Metagenomic sequencing is a promising approach for identifying and characterizing organisms and their functional characteristics in complex, polymicrobial infections, such as airway infections in people with cystic fibrosis. These analyses a
Externí odkaz:
https://doaj.org/article/aa353231eef24d6ba4bb9100acd19923
Autor:
Hillary S. Hayden, Susana Matamouros, Kyle R. Hager, Mitchell J. Brittnacher, Laurence Rohmer, Matthew C. Radey, Eli J. Weiss, Katie B. Kim, Michael A. Jacobs, Elizabeth H. Sims-Day, Min Yue, Mussaret B. Zaidi, Dieter M. Schifferli, Shannon D. Manning, Judd L. Walson, Samuel I. Miller
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT Salmonella enterica serovar Typhimurium is one of the most common S. enterica serovars associated with U.S. foodborne outbreaks. S. Typhimurium bacteria isolated from humans exhibit wide-ranging virulence phenotypes in inbred mice, leading t
Externí odkaz:
https://doaj.org/article/db54af932ed441378875a50e1fe8f57f
Publikováno v:
mBio, Vol 6, Iss 3 (2015)
ABSTRACT HAMP domains are α-helical coiled coils that often transduce signals from extracytoplasmic sensing domains to cytoplasmic domains. Limited structural information has resulted in hypotheses that specific HAMP helix movement changes downstrea
Externí odkaz:
https://doaj.org/article/9667a86201c048a4a331292c9434ce9c
Autor:
Kyle R. Hager, Lucas R. Hoffman, Daniel H. Leung, Samuel I. Miller, Sonya L. Heltshe, Mitchell J. Brittnacher, Alexander Eng, Bryan D Martin, Eli J. Weiss, Elhanan Borenstein, Christopher E. Pope, Hillary S. Hayden, Anh T. Vo
Publikováno v:
Nature medicine
Most infants with cystic fibrosis (CF) have pancreatic exocrine insufficiency that results in nutrient malabsorption and requires oral pancreatic enzyme replacement. Newborn screening for CF has enabled earlier diagnosis, nutritional intervention and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052e8fc65233a1c204b17cac9ab5ed14
http://europepmc.org/articles/PMC7018602
http://europepmc.org/articles/PMC7018602
Autor:
Daniel H. Leung, Alexander Eng, Eli J. Weiss, Lucas R. Hoffman, Hillary S. Hayden, Elhanan Borenstein, Mitchell J. Brittnacher, Christopher E. Pope, Daniel Raftery, Samuel I. Miller, Sonya L. Heltshe, Kyle R. Hager, Anh T. Vo
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-17 (2021)
BMC Microbiology
BMC Microbiology
Background Infants with cystic fibrosis (CF) suffer from gastrointestinal (GI) complications, including pancreatic insufficiency and intestinal inflammation, which have been associated with impaired nutrition and growth. Recent evidence identified al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3a1d13a43ec1ce63df3c7ec7b86c0b
https://doi.org/10.1186/s12866-021-02305-z
https://doi.org/10.1186/s12866-021-02305-z
Autor:
Samuel I. Miller, Hillary S. Hayden, Adeline M. Hajjar, Mitchell J. Brittnacher, Naseer Sangwan, Piper M. Treuting, Stacey M Meeker, Charles W. Frevert, Eli J. Weiss, Christopher E. Pope, Kevin S Mears, Anh T. Vo, Lucas R. Hoffman, Nicholas Tolley, Kyle R. Hager, Jisun Paik
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 1, p e1008251 (2020)
PLoS Pathogens, Vol 16, Iss 1, p e1008251 (2020)
Patients with cystic fibrosis (CF) have altered fecal microbiomes compared to those of healthy controls. The magnitude of this dysbiosis correlates with measures of CF gastrointestinal (GI) disease, including GI inflammation and nutrient malabsorptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5a2e7770adcec33eaf74752b2d8152
http://europepmc.org/articles/PMC6994172
http://europepmc.org/articles/PMC6994172
Autor:
Anne M. Stevens, Jeffrey S. McLean, Camille Baltuck, Hannah Leahey, Mitchell J. Brittnacher, Brian G. Leroux, Hillary S. Hayden, Sarah Ringold, Joseph Kelly, Peggy Lee, Elizabeth K Velan, Sriharsha Grevich, Kyle R. Hager, Joel Berg, Anne Reeves, Samuel I. Miller, Richard P. Darveau, Gretchen Henstorf, Amy Kim
Publikováno v:
Pediatric Rheumatology Online Journal
Pediatric Rheumatology Online Journal, Vol 17, Iss 1, Pp 1-9 (2019)
Pediatric Rheumatology Online Journal, Vol 17, Iss 1, Pp 1-9 (2019)
Background The oral microbiota has been implicated in the pathogenesis of rheumatoid arthritis through activation of mucosal immunity. This study tested for associations between oral health, microbial communities and juvenile idiopathic arthritis (JI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079002aa0c4d006b92ed4caf6562309d
https://doi.org/10.1186/s12969-019-0387-5
https://doi.org/10.1186/s12969-019-0387-5
Autor:
John B. Ochieng, Jennifer R. Verani, Joel M. Montgomery, Allan Audi, Jane Juma, Judd L. Walson, Hillary S. Hayden, Grace John-Stewart, Matthew C. Radey, Kyle R. Hager, Barry S. Fields, Jim Katieno, Samuel I. Miller, Godfrey Bigogo, Adam Akullian
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006156 (2018)
PLoS neglected tropical diseases, 12(1):e0006156. Public Library of Science
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006156 (2018)
PLoS neglected tropical diseases, 12(1):e0006156. Public Library of Science
Non-typhoidal Salmonella (NTS) is a leading cause of bloodstream infections in Africa, but the various contributions of host susceptibility versus unique pathogen virulence factors are unclear. We used data from a population-based surveillance platfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80db2277f80aecda7a66a8e2147408d
https://pubmed.ncbi.nlm.nih.gov/29329299
https://pubmed.ncbi.nlm.nih.gov/29329299
Autor:
Nicholas W. Keiser, Joann M. Kinyon, Thomas J. Lynch, Weihong Zhou, John F. Engelhardt, Xingshen Sun, Yaling Yi, Scott R. Tyler, J. Adam Goeken, Yulong Zhang, Yi Song, Timothy S. Frana, Xiaoming Liu, Lucas R. Hoffman, Kalpaj R. Parekh, Mitchell J. Brittnacher, Weiliang Xie, Alicia K. Olivier, Hongshu Sui, Bo Liang, David K. Meyerholz, Xiaoyan Wang, Samuel I. Miller, Danielle Fligg, Kyle R. Hager, John T. Fisher, Zoe A. Stewart, Paul M. Kaminsky, Ziying Yan, Christopher E. Pope, Hillary S. Hayden, Matthew C. Radey
Publikováno v:
The American Journal of Pathology. 184:1309-1322
Cystic fibrosis (CF) is a multiorgan disease caused by loss of a functional cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel in many epithelia of the body. Here we report the pathology observed in the gastrointestinal organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46044f30232ec493d56a58b563aaca07
https://doi.org/10.1016/j.ajpath.2014.01.035
https://doi.org/10.1016/j.ajpath.2014.01.035