Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kyle R Puhger"'
Autor:
Jacob H Wilmot, Cassiano RAF Diniz, Ana P Crestani, Kyle R Puhger, Jacob Roshgadol, Lin Tian, Brian Joseph Wiltgen
Publikováno v:
eLife, Vol 12 (2024)
Locus coeruleus (LC) projections to the hippocampus play a critical role in learning and memory. However, the precise timing of LC-hippocampus communication during learning and which LC-derived neurotransmitters are important for memory formation in
Externí odkaz:
https://doaj.org/article/6f2c6ee39f484ce0bb327e24868fdbe4
Autor:
Lucas Matt, Lyndsey M. Kirk, George Chenaux, David J. Speca, Kyle R. Puhger, Michael C. Pride, Mohammad Qneibi, Tomer Haham, Kristopher E. Plambeck, Yael Stern-Bach, Jill L. Silverman, Jacqueline N. Crawley, Johannes W. Hell, Elva Díaz
Publikováno v:
Cell Reports, Vol 22, Iss 9, Pp 2246-2253 (2018)
Summary: Altering AMPA receptor (AMPAR) content at synapses is a key mechanism underlying the regulation of synaptic strength during learning and memory. Previous work demonstrated that SynDIG1 (synapse differentiation-induced gene 1) encodes a trans
Externí odkaz:
https://doaj.org/article/22b1ceb0718049de9bca5dfd4fe626ec
Autor:
Mark von Zastrow, Ruqiang Liang, Chunyang Dong, Junqing Sun, Joshua D. Berke, Tommaso Patriarchi, Carolyn M.O. Davis, Brian J. Wiltgen, Aaron Marley, Ali Mohebi, Kyle R. Puhger, Lin Tian, Grace O. Mizuno
Publikováno v:
Nature methods
Genetically encoded dopamine sensors based on green fluorescent protein (GFP) enable high-resolution imaging of dopamine dynamics in behaving animals. However, these GFP-based variants cannot be readily combined with commonly used optical sensors and
Autor:
Yusuke Teratani-Ota, Sonya E. Nemes, Jamie N. Krueger, Jacob H. Wilmot, Ana Paula Crestani, Kyle R. Puhger, Brian J. Wiltgen, Marrisa M. Lafreniere
Publikováno v:
Neurobiol Learn Mem
The hippocampus plays an essential role in the formation and retrieval of episodic memories in humans and contextual memories in animals. However, amnesia is not always observed when this structure is compromised. To determine why this is the case, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13eae5fd6c7e6d5a69681e9a6df2cef3
https://escholarship.org/uc/item/9p44c7dd
https://escholarship.org/uc/item/9p44c7dd
Autor:
Kyle R. Puhger, Brian J. Wiltgen, Yusuke Teratani-Ota, Sonya E. Nemes, Jamie N. Krueger, Jacob H. Wilmot, Lafreniere M
The current study determined if inactivation of the dorsal hippocampus impairs the retrieval of newly formed context fear memories. This region was silencing by activating inhibitory neurons or by hyperpolarizing pyramidal cells directly. When inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4bd1dcde8c0674b2961da350ee3e018
https://doi.org/10.1101/843342
https://doi.org/10.1101/843342
Autor:
Lyndsey M. Kirk, Kyle R. Puhger, David J. Speca, Michael C. Pride, Jill L. Silverman, Yael Stern-Bach, Lucas Matt, Johannes W. Hell, Jacqueline N. Crawley, Elva D Diaz, Tomer Haham, George Chenaux, Kristopher E. Plambeck, Mohammad Qneibi
Publikováno v:
Cell Reports, Vol 22, Iss 9, Pp 2246-2253 (2018)
Cell reports, vol 22, iss 9
Cell reports, vol 22, iss 9
Summary: Altering AMPA receptor (AMPAR) content at synapses is a key mechanism underlying the regulation of synaptic strength during learning and memory. Previous work demonstrated that SynDIG1 (synapse differentiation-induced gene 1) encodes a trans
Autor:
Pamela J. Lein, Bruce D. Hammock, Kyle R. Puhger, Donald A. Bruun, Jill L. Silverman, Jacqueline N. Crawley, Mark R. McCoy, Brenna M. Flannery
Publikováno v:
Flannery, Brenna M; Silverman, Jill L; Bruun, Donald A; Puhger, Kyle R; McCoy, Mark R; Hammock, Bruce D; et al.(2015). Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine.. Neurotoxicology and teratology, 47, 36-45. doi: 10.1016/j.ntt.2014.10.008. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2r38b42x
Tetramethylenedisulfotetramine (TETS) is a potent convulsant poison that is thought to trigger seizures by inhibiting the function of the type A gamma-aminobutyric acid receptor (GABAAR). Acute intoxication with TETS can cause vomiting, convulsions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defba11ff5c22577c0872bcd7d500ee6
https://europepmc.org/articles/PMC4291292/
https://europepmc.org/articles/PMC4291292/
Autor:
J. E. Hayes, Michael C. Pride, Hanna M. Butler-Struben, Steven K. Baker, Jacqueline N. Crawley, Kyle R. Puhger, Jill L. Silverman
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 40(9)
Autism spectrum disorder (ASD) is diagnosed by two core behavioral criteria, unusual reciprocal social interactions and communication, and stereotyped, repetitive behaviors with restricted interests. Excitatory/inhibitory imbalance is a prominent hyp
Autor:
E. Sahagun, Jacqueline N. Crawley, Kyle R. Puhger, Michael C. Pride, Jill L. Silverman, Marjorie Solomon, Karen L. Bales, Suma Jacob, Rebecca H. Larke, Sally P. Mendoza
Publikováno v:
Translational Psychiatry
Bales, KL; Solomon, M; Jacob, S; Crawley, JN; Silverman, JL; Larke, RH; et al.(2014). Long-term exposure to intranasal oxytocin in a mouse autism model. Translational Psychiatry, 4(11). doi: 10.1038/tp.2014.117. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7f68j42w
Bales, KL; Solomon, M; Jacob, S; Crawley, JN; Silverman, JL; Larke, RH; et al.(2014). Long-term exposure to intranasal oxytocin in a mouse autism model. Translational Psychiatry, 4(11). doi: 10.1038/tp.2014.117. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7f68j42w
© 2014 Macmillan Publishers Limited All rights reserved. Oxytocin (OT) is a neuropeptide involved in mammalian social behavior. It is currently in clinical trials for the treatment of autism spectrum disorder (ASD). Previous studies in healthy roden