Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kyle P. Sullivan"'
Autor:
Kyle A. Sullivan, Matthew Lane, Mikaela Cashman, J. Izaak Miller, Mirko Pavicic, Angelica M. Walker, Ashley Cliff, Jonathon Romero, Xuejun Qin, Niamh Mullins, Anna Docherty, Hilary Coon, Douglas M. Ruderfer, International Suicide Genetics Consortium, VA Million Veteran Program, MVP Suicide Exemplar Workgroup, Michael R. Garvin, John P. Pestian, Allison E. Ashley-Koch, Jean C. Beckham, Benjamin McMahon, David W. Oslin, Nathan A. Kimbrel, Daniel A. Jacobson, David Kainer
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Genome-wide association studies (GWAS) identify genetic variants underlying complex traits but are limited by stringent genome-wide significance thresholds. We present GRIN (Gene set Refinement through Interacting Networks), which increases
Externí odkaz:
https://doaj.org/article/f343f4bdee8040aa88cb30c2c4276f5a
Autor:
Max J. Sevcik, Jacob Golson, Gabriel Bjerke, Isaac Snyder, Gage Taylor, Finnegan Wilson, Grace I. Rabinowitz, Dylan J. Kline, Michael D. Grapes, Kyle T. Sullivan, Jonathan L. Belof, Veronica Eliasson
Publikováno v:
HardwareX, Vol 17, Iss , Pp e00515- (2024)
Material extrusion Additive Manufacturing (AM), is one of the most widely practiced methods of AM. Fused Filament Fabrication (FFF) is what most associate with AM, as it is relatively inexpensive, and highly accessible, involving feeding plastic fila
Externí odkaz:
https://doaj.org/article/33542fc3d40948a987cc59d1b3591a2e
Autor:
Thaddeus J. Kunkel, Alice Townsend, Kyle A. Sullivan, Jean Merlet, Edward H. Schuchman, Daniel A. Jacobson, Andrew P. Lieberman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The intracellular cholesterol transporter NPC1 functions in late endosomes and lysosomes to efflux unesterified cholesterol, and its deficiency causes Niemann–Pick disease Type C, an autosomal recessive lysosomal disorder characterized by
Externí odkaz:
https://doaj.org/article/c8b6dbf7e23943d38d1303c4f334e573
Autor:
Kevin R. Cope, Erica T. Prates, John I. Miller, Omar N.A. Demerdash, Manesh Shah, David Kainer, Ashley Cliff, Kyle A. Sullivan, Mikaela Cashman, Matthew Lane, Anna Matthiadis, Jesse Labbé, Timothy J. Tschaplinski, Daniel A. Jacobson, Udaya C. Kalluri
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1122-1139 (2023)
For plants, distinguishing between mutualistic and pathogenic microbes is a matter of survival. All microbes contain microbe-associated molecular patterns (MAMPs) that are perceived by plant pattern recognition receptors (PRRs). Lysin motif receptor-
Externí odkaz:
https://doaj.org/article/08b84a12ebbc4beca12e112ad6d1c4e8
Autor:
Mirko Pavicic, Angelica M. Walker, Kyle A. Sullivan, John Lagergren, Ashley Cliff, Jonathon Romero, Jared Streich, Michael R. Garvin, John Pestian, Benjamin McMahon, David W. Oslin, Jean C. Beckham, Nathan A. Kimbrel, Daniel A. Jacobson
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionDespite a recent global decrease in suicide rates, death by suicide has increased in the United States. It is therefore imperative to identify the risk factors associated with suicide attempts to combat this growing epidemic. In this stud
Externí odkaz:
https://doaj.org/article/c1610b9782bd436caedb89b98091ebb4
Autor:
Cassidy T. Burke, Iuliia Vitko, Justyna Straub, Elsa O. Nylund, Agnieszka Gawda, Kathryn Blair, Kyle A. Sullivan, Lara Ergun, Matteo Ottolini, Manoj K. Patel, Edward Perez-Reyes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14467 (2023)
Epileptogenesis is characterized by intrinsic changes in neuronal firing, resulting in hyperactive neurons and the subsequent generation of seizure activity. These alterations are accompanied by changes in gene transcription networks, first with the
Externí odkaz:
https://doaj.org/article/20ab385d109b4165b40fbdef2a460e0f
Autor:
Kyle A. Sullivan, Iuliia Vitko, Kathryn Blair, Ronald P. Gaykema, Madison J. Failor, Jennifer M. San Pietro, Deblina Dey, John M. Williamson, Ruth L. Stornetta, Jaideep Kapur, Edward Perez-Reyes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11347 (2023)
Over a third of patients with temporal lobe epilepsy (TLE) are not effectively treated with current anti-seizure drugs, spurring the development of gene therapies. The injection of adeno-associated viral vectors (AAV) into the brain has been shown to
Externí odkaz:
https://doaj.org/article/6bb12ebef86b4b18b39226253559cc90
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
Circadian modulation of learning and memory efficiency is an evolutionarily conserved phenomenon, occurring in organisms ranging from invertebrates to higher mammalian species, including humans. While the suprachiasmatic nucleus (SCN) of the hypothal
Externí odkaz:
https://doaj.org/article/f53ec6fa98bf486da72b889c7f29715b
Autor:
Kyle P. Sullivan, Carina J. Gronlund, Marie S. O’Neill, Yonathan Kefelegn, Lorraine L. Cameron
Publikováno v:
Maturitas. 114:54-59
Cold and hot weather are associated with mortality and morbidity. Although the burden of temperature-associated mortality may shift towards high temperatures in the future, cold temperatures may represent a greater current-day problem in temperate ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25b9da55e2f7c430128c75bf7b1a240
https://doi.org/10.1016/j.maturitas.2018.06.002
https://doi.org/10.1016/j.maturitas.2018.06.002