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pro vyhledávání: '"Kyle N. Stearns"'
Autor:
Phineus R. L. Markwick, Marco Tonelli, Brian Fuglestad, Elizabeth A. Komives, Kyle N. Stearns, R. Bryn Fenwick, Lindsey D. Handley
Publikováno v:
Scientific Reports
Although serine proteases are found ubiquitously in both eukaryotes and prokaryotes, and they comprise the largest of all of the peptidase families, their dynamic motions remain obscure. The backbone dynamics of the coagulation serine protease, apo-t
Publikováno v:
Biophysical Journal. (2):649a
The coagulation cascade is critical to wound healing, but must be well regulated to prevent pathological clot formation. We previously investigated the backbone dynamics of a key component in this cascade, thrombin, and found that the loops surroundi