Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kyle N. Cowan"'
Autor:
Emily Freeman, Stéphanie Langlois, Marcos F. Leyba, Tarek Ammar, Zacharie Léger, Hugh J. McMillan, Jean-Marc Renaud, Bernard J. Jasmin, Kyle N. Cowan
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background Duchenne muscular dystrophy (DMD) is associated with impaired muscle regeneration, progressive muscle weakness, damage, and wasting. While the cause of DMD is an X-linked loss of function mutation in the gene encoding dystrophin,
Externí odkaz:
https://doaj.org/article/26454c7be8214472a0a10cfc640b0b48
Publikováno v:
Radiology Case Reports, Vol 17, Iss 5, Pp 1558-1562 (2022)
Horseshoe lung (HL) is a rare congenital anomaly that has been classically associated with Scimitar syndrome. Very few cases have been described in the context of the VACTERL spectrum. We present a case of a newborn girl with mesocardia, tracheoesoph
Externí odkaz:
https://doaj.org/article/b46a2adbaa1241d9893dedc322ebb327
Autor:
Xiao Xiang, Huy-Dung Hoang, Victoria H. Gilchrist, Stéphanie Langlois, Tommy Alain, Kyle N. Cowan
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-15 (2022)
Abstract Rhabdomyosarcoma (RMS) is a deadly cancer of skeletal muscle origin. Pannexin 1 (PANX1) is down-regulated in RMS and increasing its levels drastically inhibits RMS progression. PANX1 upregulation thus represents a prospective new treatment s
Externí odkaz:
https://doaj.org/article/41fb1fb1994e45e6919f3b7ece5e8a26
Autor:
Huy-Dung Hoang, Tyson E. Graber, Jian-Jun Jia, Nasana Vaidya, Victoria H. Gilchrist, Xiao Xiang, Wencheng Li, Kyle N. Cowan, Christos G. Gkogkas, Maritza Jaramillo, Seyed Mehdi Jafarnejad, Tommy Alain
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 4010-4023.e5 (2019)
Summary: Residual cell-intrinsic innate immunity in cancer cells hampers infection with oncolytic viruses. Translational control of mRNA is an important feature of innate immunity, yet the identity of translationally regulated mRNAs functioning in ho
Externí odkaz:
https://doaj.org/article/d0ba72a6fd26432394fca51a4c7a5ad3
Autor:
Stéphanie Langlois, Marie-Eve St-Pierre, Stephen H. Holland, Xiao Xiang, Emily Freeman, Hisham Mohamed, Ahmet Cem Dural, Ahmed Hammad, Sanaz Karami, Chloé van de Panne, Kyle N. Cowan
Publikováno v:
Journal of Cancer. 14:689-706
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3307ccc2bc315049898d2daccbbb0acc
https://doi.org/10.7150/jca.79552
https://doi.org/10.7150/jca.79552
Publikováno v:
Canadian Journal of Diabetes. 47:190-192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f84a890739a9239df88c3b56a895075
https://doi.org/10.1016/j.jcjd.2022.08.006
https://doi.org/10.1016/j.jcjd.2022.08.006
Publikováno v:
Journal of Pediatric Surgery. 57:866-870
Adequate tissue biopsy is essential for diagnosis and risk stratification of neuroblastoma (NB). Historically, NB diagnosis has relied on tissue obtained via surgical biopsy. However, core needle biopsy may provide a safe and adequate method of obtai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b8c2b65e89abbd07b0c9c7111f8978
https://doi.org/10.1016/j.jpedsurg.2021.12.032
https://doi.org/10.1016/j.jpedsurg.2021.12.032
Autor:
Emily Freeman, Stéphanie Langlois, Kaylee Scott, Aymeric Ravel‐Chapuis, Bernard J. Jasmin, Kyle N. Cowan
Publikováno v:
Journal of cellular physiologyREFERENCES. 237(10)
The development and regeneration of skeletal muscle are mediated by satellite cells (SCs), which ensure the efficient formation of myofibers while repopulating the niche that allows muscle repair following injuries. Pannexin 1 (Panx1) channels are ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6ba2bffc9eb501aa8300ce81a49744
https://pubmed.ncbi.nlm.nih.gov/35938715
https://pubmed.ncbi.nlm.nih.gov/35938715
Autor:
Tara E. Crawford Parks, Bernard J. Jasmin, Shekoufeh Almasi, Kyle N. Cowan, Alex MacKenzie, Aymeric Ravel-Chapuis, Jocelyn Côté
Publikováno v:
Cellular Oncology. 44:851-870
Recent work has highlighted the therapeutic potential of targeting autophagy to modulate cell survival in a variety of diseases including cancer. Recently, we found that the RNA-binding protein Staufen1 (STAU1) is highly expressed in alveolar rhabdom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31cfb315f393833e2653eb33d4d99ddf
https://doi.org/10.1007/s13402-021-00607-y
https://doi.org/10.1007/s13402-021-00607-y
Autor:
Kyle N. Cowan, Tommy Alain, Stephen Baird, Xiao Xiang, Stéphanie Langlois, Tyson E. Graber, Marie-Eve St-Pierre, Stephanie L. Fowler, Anna Blinder, Steffany A. L. Bennett, Philippe Charron
Publikováno v:
Oncogene
Rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children, is an aggressive cancer with a poor prognosis. Despite current management, the 5-year survival rate for patients with metastatic RMS is ∼30%; underscoring the need to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a574e364a2e8fd2a23097f0948b69da
http://europepmc.org/articles/PMC7946643
http://europepmc.org/articles/PMC7946643