Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kyle Mohler"'
Autor:
Ida Ang, Muhammad Sulaiman Yousafzai, Vikrant Yadav, Kyle Mohler, Jesse Rinehart, Nikolaos Bouklas, Michael Murrell
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 026109-026109-13 (2024)
During cancer pathogenesis, cell-generated mechanical stresses lead to dramatic alterations in the mechanical and organizational properties of the extracellular matrix (ECM). To date, contraction of the ECM is largely attributed to local mechanical s
Externí odkaz:
https://doaj.org/article/a0317bb3a9af4c7a9eca9eda5ce83f5c
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 8, Pp 1-18 (2023)
Abstract Over the past two decades, synthetic biological systems have revolutionized the study of cellular physiology. The ability to site‐specifically incorporate biologically relevant non‐standard amino acids using orthogonal translation system
Externí odkaz:
https://doaj.org/article/85d65118eae1479585f4602431d54ea4
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Protein phosphorylation is a ubiquitous post-translational modification used to regulate cellular processes and proteome architecture by modulating protein-protein interactions. Here the authors optimize genetically encoded phosphothreonine to study
Externí odkaz:
https://doaj.org/article/4524495ba12546348e670f788fe32025
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Bacterial antibiotic persistence is a transient physiological state wherein cells become dormant and thereby evade being killed by antibiotics. Once the antibiotic is removed, bacterial persisters are able to resuscitate and repopulate.
Externí odkaz:
https://doaj.org/article/c1ef9d2b186d43299520d29a1d1b62e9
Autor:
Paul Kelly, Nicholas Backes, Kyle Mohler, Christopher Buser, Arundhati Kavoor, Jesse Rinehart, Gregory Phillips, Michael Ibba
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Mechanisms have evolved to prevent errors in replication, transcription, and translation of genetic material, with translational errors occurring most frequently. Errors in protein synthesis can occur at two steps, during tRNA aminoacylation
Externí odkaz:
https://doaj.org/article/04243a06d1b34fd4a575aaced56d4984
Autor:
Brandon M. Gassaway, Jiaming Li, Ramin Rad, Julian Mintseris, Kyle Mohler, Tyler Levy, Mike Aguiar, Sean A. Beausoleil, Joao A. Paulo, Jesse Rinehart, Edward L. Huttlin, Steven P. Gygi
Publikováno v:
Nat Methods
Mass-spectrometry-based phosphoproteomics has become indispensable for understanding cellular signaling in complex biological systems. Despite the central role of protein phosphorylation, the field still lacks inexpensive, regenerable, and diverse ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52469f1062cd0a7b82f7270dbfda982
https://europepmc.org/articles/PMC9847208/
https://europepmc.org/articles/PMC9847208/
Publikováno v:
bioRxiv
Interactions between proteins from intracellular pathogens and host proteins in an infected cell are often mediated by post-translational modifications encoded in the host proteome. Identifying protein modifications, such as phosphorylation, that dic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bd1c8d659679c1561f55636ec94b3a
https://europepmc.org/articles/PMC9536036/
https://europepmc.org/articles/PMC9536036/
Autor:
Michael Ibba, Tammy J. Bullwinkle, Jesse Rinehart, Kyle Mohler, Kym F. Faull, Kaeli F. Loeb, Nien-Ching Han
Publikováno v:
Journal of Biological Chemistry. 295:1402-1410
β-N-methylamino-l-alanine (BMAA) is a nonproteinogenic amino acid that has been associated with neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD). BMAA has been found in human protein extracts; ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27c22215bad6cb693b86e740c88c338
https://doi.org/10.1016/s0021-9258(17)49898-x
https://doi.org/10.1016/s0021-9258(17)49898-x
Publikováno v:
Nature communications. 13(1)
Protein phosphorylation is a ubiquitous post-translational modification used to regulate cellular processes and proteome architecture by modulating protein-protein interactions. The identification of phosphorylation events through proteomic surveilla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db33f3c57a73bd89600b472d53c5650
https://pubmed.ncbi.nlm.nih.gov/36433969
https://pubmed.ncbi.nlm.nih.gov/36433969
Autor:
Nien-Ching Han, Tammy J. Bullwinkle, Kaeli F. Loeb, Kym F. Faull, Kyle Mohler, Jesse Rinehart, Michael Ibba
Publikováno v:
Journal of Biological Chemistry. 298:102544
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::712aef4d5291eeb0e95659c2d6490720
https://doi.org/10.1016/j.jbc.2022.102544
https://doi.org/10.1016/j.jbc.2022.102544