Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Kyle MA"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-13 (2024)
Abstract Smac mimetic compounds (SMCs) are small molecule drugs that sensitize cancer cells to TNF-α-induced cell death and have multiple immunostimulatory effects through alterations in NF-κB signaling. The combination of SMCs with immunotherapies
Externí odkaz:
https://doaj.org/article/e7dfa93325ff4ad39a2ad7f101b6277c
Autor:
Rajinder Bhardwaj, Mary Donohue, Jennifer Madonia, Matt S. Anderson, Kyle Matschke, Richard Bertz, Robert Croop, Jing Liu
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 10, Pp n/a-n/a (2024)
Abstract Zavegepant, a high‐affinity, selective, small‐molecule calcitonin gene‐related peptide receptor antagonist, is approved as a nasal spray for acute treatment of migraine in adults. This phase I, open‐label, single‐center, single‐p
Externí odkaz:
https://doaj.org/article/e5059d30e427441d9f93ccf998c59d45
Publikováno v:
International Journal of Sports Physical Therapy, Vol 19, Iss 10 (2024)
# Context Musculoskeletal disorders (MSKD) are currently the leading contributor to disability worldwide. Unlike other prevalent and disabling healthcare conditions such as CVD, risk factors associated with MSKD are not commonly discussed or integra
Externí odkaz:
https://doaj.org/article/d7f54b134b394550834fb4a7749e4d91
Autor:
Evan Mostafa, MD, Aaron Hui, BS, Boudewijn Aasman, BS, Kamlesh Chowdary, BS, Kyle Mani, BS, Edward Mardakhaev, MD, Richard Zampolin, MD, Einat Blumfield, MD, Jesse Berman, MD, Rafael De La Garza Ramos, MD, Mitchell Fourman, MD, Reza Yassari, MD, Ananth Eleswarapu, MD, Parsa Mirhaji, PhD
Publikováno v:
North American Spine Society Journal, Vol 19, Iss , Pp 100513- (2024)
Background: Metastasis to the spinal column is a common complication of malignancy, potentially causing pain and neurologic injury. An automated system to identify and refer patients with spinal metastases can help overcome barriers to timely treatme
Externí odkaz:
https://doaj.org/article/86ac1f741bb64f588c91a875a064e3a4
Autor:
Maryam Ghashghaei, Yilin Liu, James Ettles, Giuseppe Bombaci, Niveditha Ramkumar, Zongmin Liu, Leo Escano, Sandra Spencer Miko, Yerin Kim, Joseph A. Waldron, Kim Do, Kyle MacPherson, Katie A. Yuen, Thilelli Taibi, Marty Yue, Aaremish Arsalan, Zhen Jin, Glenn Edin, Aly Karsan, Gregg B. Morin, Florian Kuchenbauer, Fabiana Perna, Martin Bushell, Ly P. Vu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Protein synthesis is frequently deregulated during tumorigenesis. However, the precise contexts of selective translational control and the regulators of such mechanisms in cancer is poorly understood. Here, we uncovered CNOT3, a subunit of t
Externí odkaz:
https://doaj.org/article/70b7701b4c0b40d88cc303cdcb9178b8
Autor:
Alana Schick, Julie M. Deleemans, Erna Alukic, Kyle Ma, Raylene A. Reimer, Jodi E. Nettleton, Jolene Wong, Faye Chleilat, Erin W. Noye Tuplin
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(9)
Mounting evidence demonstrates that paternal diet programs offspring metabolism. However, the contribution of a pre-conception paternal high protein (HP) diet to offspring metabolism, gut microbiota, and epigenetic changes remains unclear. Here we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081854d5d1d3c253e6e735bd4284826c
https://pubmed.ncbi.nlm.nih.gov/34405464
https://pubmed.ncbi.nlm.nih.gov/34405464
Autor:
Marina Aweeda, Carly Fassler, Alexander N. Perez, Alexis Miller, Kavita Prasad, Kayvon F. Sharif, James S. Lewis, Jr, Kim A. Ely, Mitra Mehrad, Sarah L. Rohde, Alexander J. Langerman, Kyle Mannion, Robert J. Sinard, James L. Netterville, Eben L. Rosenthal, Michael C. Topf
Publikováno v:
Journal of Pathology Informatics, Vol 15, Iss , Pp 100404- (2024)
Background: Positive margins are frequently observed in total laryngectomy (TL) specimens. Effective communication of margin sampling sites and final margin status between surgeons and pathologists is crucial. In this study, we evaluate the utility o
Externí odkaz:
https://doaj.org/article/c2f9e7eeee744d11b9317dd1d5fcd5f4
Autor:
Pawel Dudzic, Dawid Chomicz, Jarosław Kończak, Tadeusz Satława, Bartosz Janusz, Sonia Wrobel, Tomasz Gawłowski, Igor Jaszczyszyn, Weronika Bielska, Samuel Demharter, Roberto Spreafico, Lukas Schulte, Kyle Martin, Stephen R. Comeau, Konrad Krawczyk
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
The naïve human antibody repertoire has theoretical access to an estimated > 1015 antibodies. Identifying subsets of this prohibitively large space where therapeutically relevant antibodies may be found is useful for development of these agents. It
Externí odkaz:
https://doaj.org/article/7c74ae2f3b3c4564ab5b22c1be596002
Publikováno v:
Frontiers in Environmental Science, Vol 12 (2024)
As organic waste is converted to usable amendments via composting, there are large CO2 emissions associated with the decomposition of organic matter via microorganisms. While the active composting phase produces the largest emissions over a short dur
Externí odkaz:
https://doaj.org/article/ae5fd678b6054a7a8b79b2ddf725cab8
Autor:
Mark A. Liebig, Francisco J. Calderon, Andrea K. Clemensen, Lisa Durso, Jessica L. Duttenhefner, Jed O. Eberly, Jonathan J. Halvorson, Virginia L. Jin, Kyle Mankin, Andrew J. Margenot, Catherine E. Stewart, Scott Van Pelt, Merle F. Vigil
Publikováno v:
Agrosystems, Geosciences & Environment, Vol 7, Iss 2, Pp n/a-n/a (2024)
Abstract Diverse patterns of climate and edaphic factors challenge detection of soil property change in the US Great Plains. Because detectable soil change can take decades, insights into the trajectory of soil properties frequently require long‐te
Externí odkaz:
https://doaj.org/article/c389bc5e91d54d4fac03f6dd3ea6e13c