Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Kyle M. Devins"'
1
Akademický článek
L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary
Autor: Kai Doberstein, Rebecca Spivak, Hunter D. Reavis, Jagmohan Hooda, Yi Feng, Paul T. Kroeger, Sarah Stuckelberger, Gordon B. Mills, Kyle M. Devins, Lauren E. Schwartz, Marcin P. Iwanicki, Mina Fogel, Peter Altevogt, Ronny Drapkin
Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
L1CAM is implicated as an important factor that enables early fallopian tube cancer precursors to seed the ovary by promoting cell survival through extracellular matrix signaling, thereby facilitating ovarian cancer growth.
Externí odkaz: https://doaj.org/article/72d15a5115e24cf6806f17c0c2a2f6ba
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2
Akademický článek
CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
Autor: Haineng Xu, Erin George, Yasuto Kinose, Hyoung Kim, Jennifer B. Shah, Jasmine D. Peake, Benjamin Ferman, Sergey Medvedev, Thomas Murtha, Carter J. Barger, Kyle M. Devins, Kurt D’Andrea, Bradley Wubbenhorst, Lauren E. Schwartz, Wei-Ting Hwang, Gordon B. Mills, Katherine L. Nathanson, Adam R. Karpf, Ronny Drapkin, Eric J. Brown, Fiona Simpkins
Publikováno v: Cell Reports Medicine, Vol 2, Iss 9, Pp 100394- (2021)
Summary: CCNE1-amplified ovarian cancers (OVCAs) and endometrial cancers (EMCAs) are associated with platinum resistance and poor survival, representing a clinically unmet need. We hypothesized that dysregulated cell-cycle progression promoted by CCN
Externí odkaz: https://doaj.org/article/317f0b4f67b94645ac9dda7eac42892d
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6
Embryonal Rhabdomyosarcoma of the Uterine Cervix
Autor: Kyle M, Devins, Robert H, Young, Mariachristina, Ghioni, Eike, Burandt, Jennifer A, Bennett, Esther, Oliva
Publikováno v: American Journal of Surgical Pathology. 46:1477-1489
Embryonal rhabdomyosarcoma of the uterine cervix (cERMS) is rare and frequently associated with DICER1 mutations. We report 94 tumors that arose in patients aged 7 to 59 (median=23) years and presented with vaginal bleeding (52), protruding vaginal m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b004786d37fedef094a10c95a761691
https://doi.org/10.1097/pas.0000000000001933
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8
BAP1 and Claudin-4, But Not MTAP, Reliably Distinguish Borderline and Low-grade Serous Ovarian Tumors From Peritoneal Mesothelioma
Autor: Kyle M, Devins, Lawrence, Zukerberg, Jaclyn C, Watkins, Yin Pun, Hung, Esther, Oliva
Publikováno v: International Journal of Gynecological Pathology. 42:159-166
Peritoneal mesothelioma (PM) and serous neoplasms can be difficult to differentiate, particularly in small biopsies. BRCA1-associated protein 1 (BAP1) is expressed in benign tissues, but over 50% of PMs demonstrate complete loss of nuclear expression
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038c0e25f7cb6a7589870f0f3c09d9a3
https://doi.org/10.1097/pgp.0000000000000877
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9
Sclerosing stromal tumour: a clinicopathological study of 100 cases of a distinctive benign ovarian stromal tumour typically occurring in the young
Autor: Jaclyn C Watkins, Robert H. Young, Kyle M Devins
Publikováno v: Histopathology. 80:360-368
AIMS Since the sclerosing stromal tumour (SST) of the ovary was first described in 1973, few studies have expanded upon its histological features or overlap with other tumours. We thus investigate these aspects based on our experience with 100 cases.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc9adebb6a4fa1d70cff724f577cc83
https://doi.org/10.1111/his.14554
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