Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Kyle L. Poulsen"'
Autor:
Hang Dong, Honglin Guo, Jing Du, Yiping Cheng, Dawei Wang, Junming Han, Zinuo Yuan, Zhenyu Yao, Ran An, Xiaoqin Wu, Kyle L. Poulsen, Zhixiang Wang, Shanshan Shao, Xiude Fan, Zhen Wang, Jiajun Zhao
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Background The relationship between obesity and non-Hodgkin’s lymphoma (NHL) was controversial, which may be due to the crudeness definition of obesity based on body mass index (BMI). As obesity and metabolic abnormalities often coexist, w
Externí odkaz:
https://doaj.org/article/cebf143ab6154cfdaa40e925643a18f2
Autor:
Mi Jeong Heo, Ji Ho Suh, Sung Ho Lee, Kyle L. Poulsen, Yu A. An, Bhagavatula Moorthy, Sean M. Hartig, David D. Moore, Kang Ho Kim
Publikováno v:
Molecular Metabolism, Vol 72, Iss , Pp 101717- (2023)
Objective: Mitophagy removes damaged mitochondria to maintain cellular homeostasis. Aryl hydrocarbon receptor (AhR) expression in the liver plays a crucial role in supporting normal liver functions, but its impact on mitochondrial function is unclear
Externí odkaz:
https://doaj.org/article/13b0b290b21c4a599188bb3f6154ef68
Autor:
Xiaohan Xu, Kyle L. Poulsen, Lijuan Wu, Shan Liu, Tatsunori Miyata, Qiaoling Song, Qingda Wei, Chenyang Zhao, Chunhua Lin, Jinbo Yang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-39 (2022)
Abstract Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive and more susceptible to developing cirrhosis and hepatocellular carcin
Externí odkaz:
https://doaj.org/article/d2c44ce0637f466aa57fcae500fa37d4
Autor:
Zinuo Yuan, Yiping Cheng, Junming Han, Dawei Wang, Hang Dong, Yingzhou Shi, Kyle L. Poulsen, Xiude Fan, Jiajun Zhao
Publikováno v:
EClinicalMedicine, Vol 51, Iss , Pp 101577- (2022)
Summary: Background: Increased body mass index (BMI) and metabolic abnormalities are controversial prognostic factors of lung cancer. However, the relationship between metabolic overweight/obesity phenotypes and hospital readmission in patients with
Externí odkaz:
https://doaj.org/article/570d361fdb75457b87922153b85639eb
Autor:
Xiude Fan, Jianguo Wu, Kyle L. Poulsen, Adam Kim, Xiaoqin Wu, Emily Huang, Tatsunori Miyata, Carlos Sanz‐Garcia, Laura E. Nagy
Publikováno v:
Hepatology Communications, Vol 5, Iss 5, Pp 830-845 (2021)
We aimed to identify a microRNA (miRNA)‐E3 ubiquitin ligase regulatory network for protein substrates enriched in cell death pathways and investigate the underlying molecular mechanisms in alcohol‐associated hepatitis (AH). An miRNA‐E3 ubiquiti
Externí odkaz:
https://doaj.org/article/f58c98a8f50e47dcaa605cccdf145872
Autor:
Kyle L. Poulsen, Xiude Fan, Christopher D. Kibler, Emily Huang, Xiaoqin Wu, Megan R. McMullen, Lin Leng, Richard Bucala, Meritxell Ventura-Cots, Josepmaria Argemi, Ramon Bataller, Laura E. Nagy
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
The chemokine system of ligands and receptors is implicated in the progression of alcohol-associated hepatitis (AH). Finding upstream regulators could lead to novel therapies. This study involved coordinated expression of chemokines in livers of heal
Externí odkaz:
https://doaj.org/article/dd2f75ec9fac4bb2bf9938363a35de8e
Autor:
Xiude Fan, Zhengwen Liu, Kyle L. Poulsen, Xiaoqin Wu, Tatsunori Miyata, Srinivasan Dasarathy, Daniel M. Rotroff, Laura E. Nagy
Publikováno v:
Nutrients, Vol 13, Iss 5, p 1592 (2021)
Background: Acute and chronic alcohol abuse has adverse impacts on both the innate and adaptive immune response, which may result in reduced resistance to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and promote the progress
Externí odkaz:
https://doaj.org/article/ce211df3dce24c15800a6b0ac29e577a
Autor:
Rebecca L. McCullough, Megan R. McMullen, Kyle L. Poulsen, Adam Kim, M. Edward Medof, Laura E. Nagy
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background and aims: Chronic ethanol exposure results in inflammation in adipose tissue; this response is associated with activation of complement as well as the development of alcohol-related liver disease (ALD). Adipose communicates with other orga
Externí odkaz:
https://doaj.org/article/246e87f1b15a4bb6ab0c5f769a1ed3e8
Autor:
Erika Y. Faraoni, Kanchan Singh, Vidhi Chandra, Olivereen Le Roux, Yulin Dai, Ismet Sahin, Baylee J. O'Brien, Lincoln N. Strickland, Le Li, Emily Vucic, Amanda N. Warner, Melissa Pruski, Trent Clark, George Van Buren, Nirav C. Thosani, John S. Bynon, Curtis J. Wray, Dafna Bar-Sagi, Kyle L. Poulsen, Lana A. Vornik, Michelle I. Savage, Shizuko Sei, Altaf Mohammed, Zhongming Zhao, Powel H. Brown, Tingting Mills, Holger K. Eltzschig, Florencia McAllister, Jennifer M. Bailey-Lundberg
Publikováno v:
Cancer research, vol 83, iss 7
The microenvironment that surrounds pancreatic ductal adenocarcinoma (PDAC) is profoundly desmoplastic and immunosuppressive. Understanding triggers of immunosuppression during the process of pancreatic tumorigenesis would aid in establishing targets
Autor:
Long Xu, Yang Yang, Yankai Wen, Jong-Min Jeong, Christoph Emontzpohl, Constance L. Atkins, Zhaoli Sun, Kyle L. Poulsen, David R. Hall, J. Steve Bynon, Bin Gao, William M. Lee, Jody Rule, Elizabeth A. Jacobsen, Hua Wang, Cynthia Ju
Publikováno v:
Journal of Hepatology. 77:344-352
Beyond the classical description of eosinophil functions in parasite infections and allergic diseases, emerging evidence supports a critical role of eosinophils in resolving inflammation and promoting tissue remodeling. However, the role of eosinophi