Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kyle L. Asfahl"'
Autor:
Lucia Grassi, Kyle L. Asfahl, Sara Van den Bossche, Ine Maenhout, Andrea Sass, Yannick Vande Weygaerde, Eva Van Braeckel, Bruno Verhasselt, Jerina Boelens, Michael M. Tunney, Ajai A. Dandekar, Tom Coenye, Aurélie Crabbé
Publikováno v:
Biofilm, Vol 7, Iss , Pp 100206- (2024)
It is increasingly recognized that interspecies interactions may modulate the pathogenicity of Pseudomonas aeruginosa during chronic lung infections. Nevertheless, while the interaction between P. aeruginosa and pathogenic microorganisms co-infecting
Externí odkaz:
https://doaj.org/article/18ff7c56d8d0412ab009cf7aca01cbfc
Publikováno v:
mSystems, Vol 7, Iss 2 (2022)
ABSTRACT In people with the genetic disease cystic fibrosis (CF), bacterial infections involving the opportunistic pathogen Pseudomonas aeruginosa are a significant cause of morbidity and mortality. P. aeruginosa uses a cell-cell signaling mechanism
Externí odkaz:
https://doaj.org/article/8db2b8db0d794b4cbb150a45e875a386
Autor:
Nicole E. Smalley, Amy L. Schaefer, Kyle L. Asfahl, Crystal Perez, E. Peter Greenberg, Ajai A. Dandekar
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT In the opportunistic pathogenic bacterium Pseudomonas aeruginosa acyl-homoserine lactone quorum sensing (QS) can activate expression of dozens to hundreds of genes depending on the strain under investigation. Many QS-activated genes code for
Externí odkaz:
https://doaj.org/article/2ef094612d40466bbbff246cb11f0fb7
Autor:
Huicong Yan, Kyle L. Asfahl, Na Li, Feng Sun, Junwei Xiao, Dongsheng Shen, Ajai A. Dandekar, Meizhen Wang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Quorum sensing (QS) regulates production of ‘public goods’ by Pseudomonas aeruginosa, which releases toxic hydrogen cyanide to constrain QS-deficient cheaters. Here, Yan et al. show that QS-proficient strains protect themselves by producing a cya
Externí odkaz:
https://doaj.org/article/80dcc52ef5834a37a2953282e4ece776
Autor:
Renae L. Cruz, Kyle L. Asfahl, Sara Van den Bossche, Tom Coenye, Aurélie Crabbé, Ajai A. Dandekar
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of airway infection in cystic fibrosis (CF) patients. P. aeruginosa employs several hierarchically arranged and interconnected quorum sensing (QS) regulatory circuits to pr
Externí odkaz:
https://doaj.org/article/3cfd45f3bc1647b5bc6bf4112cef5bcb
Autor:
Kyle L. Asfahl, Martin Schuster
Publikováno v:
Frontiers in Microbiology, Vol 8 (2018)
In the opportunistic pathogen Pseudomonas aeruginosa, quorum sensing (QS) via acyl-homoserine lactone (AHL) signals coordinates virulence gene expression. AHL signals must reach a critical threshold before enough is bound by cognate regulators LasR a
Externí odkaz:
https://doaj.org/article/484b836350e14cc5a8bccf14afc561fa
Autor:
Perez C, E. P. Greenberg, Amy L. Schaefer, Ajai A. Dandekar, Kyle L. Asfahl, Nicole E. Smalley
The bacterium Pseudomonas aeruginosa is an opportunistic pathogen and it thrives in many different saprophytic habitats. In this bacterium acyl-homoserine lactone quorum sensing (QS) can activate expression of over 100 genes, many of which code for e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0ea523ba02803d42c3eebcff9d515f8
https://doi.org/10.1101/2021.07.01.450773
https://doi.org/10.1101/2021.07.01.450773
Autor:
Kyle L. Asfahl, Ajai A. Dandekar
Publikováno v:
Journal of Cystic Fibrosis. 20:S199-S200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::589ebd85036bf31d83355749f34f94bc
https://doi.org/10.1016/s1569-1993(21)01849-x
https://doi.org/10.1016/s1569-1993(21)01849-x
Autor:
Sierra Smith, Marianne Piochon, Kyle L. Asfahl, Hillary S. Hayden, Ajai A. Dandekar, Patrick N. Ball, Eric Déziel, Josephine R. Chandler, Natalie A. Eppler, Emily Tuma, Stephanie Moon, Jennifer R. Klaus, Nicole E. Smalley, Marie-Christine Groleau, Charles Gauthier, Charlotte Majerczyk
Publikováno v:
Appl Environ Microbiol
The bacterium Burkholderia thailandensis produces an arsenal of secondary metabolites that have diverse structures and roles in the ecology of this soil-dwelling bacterium. In coculture experiments, B. thailandensis strain E264 secretes an antimicrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a45c7050f417518465b36afaae04318
https://doi.org/10.1128/aem.01452-20
https://doi.org/10.1128/aem.01452-20
Autor:
Jennifer R Klaus, Charlotte Majerczyk, Stephanie Moon, Natalie A. Epplera, Sierra Smith, Emily Tuma, Marie-Christine Groleau, Kyle L. Asfahl, Nicole E. Smalley, Hillary S. Hayden, Marianne Piochon, Patrick Ball, Ajai A. Dandekar, Charles Gauthier, Eric Déziel, Josephine R. Chandler
The bacteriumBurkholderia thailandensisproduces an arsenal of secondary metabolites that have diverse structures and roles in the ecology of this soil-dwelling bacterium. In liquid co-culture experiments,B. thailandensissecretes an antimicrobial that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd37b5ae9b8aacf35749a08ae5d93c90
https://doi.org/10.1101/2020.05.27.120295
https://doi.org/10.1101/2020.05.27.120295